Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT03579 , Transcription intermediary factor 1-alpha
Gene Name TRIM24
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O15164
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017  Protein ID: PT03579
 
Compound ID Compound Name Compound Formula
CP0250495
N-[6-[3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C32H42N4O8S
 1
1
EC50 = 50 nM
   TI
   LI
   LO
   TS
CP0409012
N-[6-[3-(4-aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C30H38N4O8S
 1
1
EC50 = 59 nM
   TI
   LI
   LO
   TS
CP0407635
N-[6-[3-(5-aminopentoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C27H36N6O6S
 1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
CP0383067
N-[6-[3-(4-aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C26H34N6O6S
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0403064
N-[6-[3-(3-aminopropoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C29H36N4O8S
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0383068
N-[6-[3-(6-aminohexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C28H38N6O6S
 1
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
CP0474186
N-[6-[3-(6-aminohexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C32H42N4O8S
 1
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
CP0398747
N-[1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)benzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C26H29N3O7S
 1
1
EC50 = 830 nM
   TI
   LI
   LO
   TS
CP0404481
N-[1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)benzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide
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C23H27N5O5S
 1
1
EC50 = 950 nM
   TI
   LI
   LO
   TS
CP0398745
N-[1,3-dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide
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C24H29N5O5S
 1
1
EC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0403062
N-[6-[3-(6-hydroxyhexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C28H37N5O7S
 1
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0459852
N-[1,3-dimethyl-2-oxo-6-[3-(oxolan-3-ylmethoxy)phenoxy]benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C24H27N5O6S
 1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0566905
N-[6-(3-ethoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide
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C22H25N5O5S
 1
1
EC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0404480
N-[6-[3-(3-methoxypropoxy)phenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide
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C24H29N5O6S
 1
1
EC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0455573
N-[6-(3-butoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide
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C24H29N5O5S
 1
1
EC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0383069
N-[6-[3-[4-(dimethylamino)butoxy]phenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C29H36N4O7S
 1
1
EC50 = 3200 nM
   TI
   LI
   LO
   TS
CP0403063
N-[1,3-dimethyl-2-oxo-6-(3-phenylmethoxyphenoxy)benzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide
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C30H29N3O7S
 1
1
EC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0545273
N-[1,3-dimethyl-2-oxo-6-(3-phenylmethoxyphenoxy)benzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide
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C27H27N5O5S
 1
1
EC50 = 4900 nM
   TI
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   TS
CP0383070
N-[1,3-dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxobenzimidazol-5-yl]cyclopropanesulfonamide
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C22H27N3O5S
 1
1
EC50 = 5000 nM
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CP0391605
tert-butyl N-[6-[3-[1,3-dimethyl-6-[(1-methylimidazol-4-yl)sulfonylamino]-2-oxobenzimidazol-5-yl]oxy-5-propoxyphenoxy]hexyl]carbamate
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C33H46N6O8S
 1
1
EC50 = 5500 nM
   TI
   LI
   LO
   TS
CP0407639
N-[1,3-dimethyl-2-oxo-6-(3-phenylmethoxyphenoxy)benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C26H25N5O5S
 1
1
EC50 = 6200 nM
   TI
   LI
   LO
   TS
CP0551607
N-[1,3-dimethyl-2-oxo-6-(4-phenylmethoxyphenoxy)benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide
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C26H25N5O5S
 1
1
EC50 > 33000 nM
   TI
   LI
   LO
   TS
CP0474187
1,3-dimethyl-5-[3-(2-methylpropoxy)phenoxy]benzimidazol-2-one
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C19H22N2O3
 1
1
EC50 > 36000 nM
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   TS