4-(1-methyl-2,4-dioxo-3-propyl-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-(2-(pyridin-2-yl)ethyl)benzenesulfonamide

4-((4-(4-(1-methyl-2,4-dioxo-3-propyl-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)phenylsulfonyl)piperazin-1-yl)methyl)benzonitrile

4-(1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-(pyridin-2-yl)benzenesulfonamide

N-(1-benzylpiperidin-4-yl)-4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)benzenesulfonamide

4-(1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-(6-methoxypyridin-3-yl)benzenesulfonamide

4-(1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-(2-(pyridin-2-yl)ethyl)benzenesulfonamide

6-(4-(4-benzylpiperazin-1-ylsulfonyl)phenyl)-1,3-dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

4-(1,3-diethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]benzenesulfonamide

6-(4-(4-((5-chlorothiophen-2-yl)methyl)piperazin-1-ylsulfonyl)phenyl)-1,3-dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

4-(1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-(2-(pyridin-2-yloxy)ethyl)benzenesulfonamide

N-[(5-methoxypyridin-2-yl)methyl]-4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)benzenesulfonamide

6-(4-(4-(3-fluorobenzyl)piperazin-1-ylsulfonyl)phenyl)-1,3-dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

6-(4-{[4-(4-bromobenzyl)piperazin-1-yl]sulfonyl}phenyl)-1,3-dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

6-(4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-ylsulfonyl)phenyl)-3-methyl-1-propyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

4-(1,3-diethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-(2-(pyridin-2-yl)ethyl)benzenesulfonamide

6-(4-(4-(3-fluorobenzyl)piperazin-1-ylsulfonyl)phenyl)-1,3-diethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

4-(1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)-N-((5-methoxypyridin-2-yl)methyl)benzenesulfonamide

propan-2-yl 4-(furan-2-yl)-2-methyl-1,4-dihydropyrimido[1,2-a]benzimidazole-3-carboxylate

N-[4,6-bis(1,3-benzodioxol-5-yl)pyridin-2-yl]acetamide

N-[2,6-bis(furan-2-yl)pyrimidin-4-yl]acetamide

N-[2,6-bis(1,3-benzodioxol-5-yl)pyrimidin-4-yl]acetamide

N-[2,6-bis(4-methoxyphenyl)pyrimidin-4-yl]propanamide

(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide

N-[2,6-bis(4-methylphenyl)pyrimidin-4-yl]acetamide

N-[2,6-bis(2,4-dimethoxyphenyl)pyrimidin-4-yl]acetamide

N-[2,6-bis(furan-2-yl)pyrimidin-4-yl]propanamide

N-[4,6-bis(4-acetylphenyl)pyridin-2-yl]acetamide

N-[4,6-bis(3,4-dimethoxyphenyl)pyridin-2-yl]acetamide

N-(2,6-dithiophen-2-ylpyrimidin-4-yl)acetamide

N-[2,6-bis(furan-2-yl)pyrimidin-4-yl]butanamide

N-[2,6-bis(furan-3-yl)pyrimidin-4-yl]acetamide

N-[2,6-bis(2,4-dimethoxyphenyl)pyrimidin-4-yl]butanamide

N-[2,6-bis(4-methoxyphenyl)pyrimidin-4-yl]butanamide

N-[2,6-bis(2,4-dimethoxyphenyl)pyrimidin-4-yl]propanamide

N-[2,6-bis(4-fluorophenyl)pyrimidin-4-yl]propanamide

N-(2,6-diphenylpyrimidin-4-yl)acetamide

N-[2,6-bis(furan-3-yl)pyrimidin-4-yl]propanamide

(2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol

N-[2,6-bis(1,3-benzodioxol-5-yl)pyrimidin-4-yl]propanamide

N-[4,6-bis(3-methoxyphenyl)pyridin-2-yl]acetamide

N-[2,6-bis[(E)-2-phenylethenyl]pyrimidin-4-yl]acetamide

N-[2,6-bis(4-fluorophenyl)pyrimidin-4-yl]acetamide

N-[2,6-bis(2-fluorophenyl)pyrimidin-4-yl]acetamide

N-[2,6-bis(4-methylphenyl)pyrimidin-4-yl]propanamide

N-[2,6-di(thiophen-3-yl)pyrimidin-4-yl]acetamide

N-[4,6-bis(4-methylphenyl)pyridin-2-yl]acetamide

N-(2,6-dithiophen-2-ylpyrimidin-4-yl)propanamide

1-[[2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-yl]amino]propan-2-ol

N-(2,6-dithiophen-2-ylpyrimidin-4-yl)butanamide

2-[1-(S)-Methyl-2-(4-methoxyphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

N-[2,6-bis(2-methoxyphenyl)pyrimidin-4-yl]propanamide

N-[2,6-bis(2-methoxyphenyl)pyrimidin-4-yl]acetamide

N-[2,6-bis(4-acetylphenyl)pyrimidin-4-yl]acetamide

N-[2,6-bis(4-chlorophenyl)pyrimidin-4-yl]propanamide

2-[[2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-yl]amino]ethanol

N-[2,6-bis(4-fluorophenyl)pyrimidin-4-yl]butanamide

N-[4,6-bis(2,5-dimethoxyphenyl)pyridin-2-yl]acetamide

2-[1-(R,S)-Methyl-2-(4-fluorophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

N-[2,6-bis(4-methylsulfanylphenyl)pyrimidin-4-yl]propanamide

N-[2,6-bis(4-acetylphenyl)pyrimidin-4-yl]propanamide

N-(2,6-diphenylpyrimidin-4-yl)propanamide

N-[2,6-bis[(E)-2-phenylethenyl]pyrimidin-4-yl]propanamide

N-[4,6-bis(4-methylphenyl)pyrimidin-2-yl]acetamide

2-[1-(R,S)-Methyl-2-(4-chlorophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

N-[2,6-bis(1,3-benzodioxol-5-yl)pyrimidin-4-yl]butanamide

N-[2,6-bis(4-methylphenyl)pyrimidin-4-yl]butanamide

N-[2,6-bis(4-chlorophenyl)pyrimidin-4-yl]acetamide

N-[2,6-di(thiophen-3-yl)pyrimidin-4-yl]propanamide

2-(furan-2-yl)-4-(furan-2-ylmethoxy)-[1,2,4]triazolo[1,5-a]quinoxaline

(CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmethyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-propionic acid

N-[4,6-bis(4-methylsulfanylphenyl)pyridin-2-yl]acetamide

[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl N-(4-fluorophenyl)carbamate

N-[2,6-bis(4-methylsulfanylphenyl)pyrimidin-4-yl]acetamide

2-[1-(R,S)-Methyl-2-(3-methoxyphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

2-[1-(R,S)-Methyl-2-phenylethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-bromo-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol

(2R,3R,4S,5R)-2-(6-amino-2-((S)-1-hydroxy-3-phenylpropan-2-ylamino)-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diol

3-(2-ethylsulfonylethyl)-8-phenyl-1-propyl-7H-purine-2,6-dione

2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]-N-pyridin-3-ylacetamide

6-Phenyl-1,3-dipropyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione

N-(4,6-diphenylpyridin-2-yl)acetamide

2-[1-(R)-Methyl-2-(4-methoxyphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

N-[2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-yl]-2-phenylacetamide

N-[4,6-bis(1,3-benzodioxol-5-yl)pyrimidin-2-yl]acetamide

N-[2,6-bis(4-chlorophenyl)pyrimidin-4-yl]butanamide

N-[4,6-bis(4-methoxyphenyl)pyridin-2-yl]acetamide

N-[4,6-bis(3,5-dimethoxyphenyl)pyridin-2-yl]acetamide

N-[2,6-bis(2-methoxyphenyl)pyrimidin-4-yl]butanamide

N-[4,6-bis(3,4,5-trimethoxyphenyl)pyridin-2-yl]acetamide

3-(2-ethylsulfanylethyl)-8-phenyl-1-propyl-7H-purine-2,6-dione

2-[1-(R)-Methyl-2-phenylethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

(2R,3R,4S,5R)-2-[6-amino-2-[1-(4-methoxyphenyl)propan-2-ylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol

2-Dimethylamino 5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

N-[2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-yl]-3-phenylpropanamide

N-[2,6-bis[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]acetamide

N-[4,6-bis(1,3-benzodioxol-5-yl)pyrimidin-2-yl]propanamide

(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-methoxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol

N-[4,6-bis(4-methylphenyl)pyrimidin-2-yl]butanamide

N-[2,6-bis(4-acetylphenyl)pyrimidin-4-yl]butanamide

3-(oxolan-2-ylmethyl)-8-phenyl-1-propyl-7H-purine-2,6-dione

N-[2,6-bis(2-fluorophenyl)pyrimidin-4-yl]butanamide

(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-hydroxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol

N-[4,6-bis[(E)-2-phenylethenyl]pyrimidin-2-yl]propanamide

N-[4,6-bis(4-methylphenyl)pyrimidin-2-yl]propanamide

N-[2,6-bis(2-fluorophenyl)pyrimidin-4-yl]propanamide

2-[1-(R)-Methyl-2-(4-bromophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

N-(4,6-diphenylpyrimidin-2-yl)cyclopentanecarboxamide

N-(2,6-diphenylpyrimidin-4-yl)butanamide

7-hydroxy-6-phenyl-1,3-dipropyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

N-[6-(5-methylfuran-2-yl)-5-pyridin-4-ylpyridin-2-yl]cyclopropanecarboxamide

N-(4-bromophenyl)-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide

N-[4-(dimethylamino)phenyl]-2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]acetamide

2-[1-(R,S)-Methyl-2-(4-bromophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

2-[1-(R,S)-Methyl-2-(4-trifluoromethylphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine

3-(2-ethylsulfinylethyl)-8-phenyl-1-propyl-7H-purine-2,6-dione

N-[2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-yl]furan-2-carboxamide

N-[2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-yl]acetamide

[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl N-phenylcarbamate

N-[4,6-bis(2-fluorophenyl)pyrimidin-2-yl]propanamide

(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-chloro-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol

7-hydroxy-6-(4-(methylsulfonyl)phenyl)-1,3-dipropyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

N-[5-cyano-6-(furan-2-yl)pyridin-2-yl]cyclopropanecarboxamide

N-[6-(2-fluorophenyl)-5-pyridin-4-ylpyrazin-2-yl]cyclopropanecarboxamide

[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl N-phenylcarbamate

2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-amine

N-[6-(furan-2-yl)-5-pyridin-4-ylpyridin-2-yl]acetamide

[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl N-thiophen-3-ylcarbamate

N-[6-(5-methylfuran-2-yl)-5-pyridin-4-ylpyrazin-2-yl]cyclopropanecarboxamide

2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-amine

N-[6-(furan-2-yl)-5-pyridin-4-ylpyrazin-2-yl]propanamide

N-[6-(furan-2-yl)-5-pyridin-4-ylpyrazin-2-yl]cyclopropanecarboxamide

N-(4-cyanophenyl)-2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]acetamide

(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-nitro-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol

1-ethyl-3-(2-ethylsulfanylethyl)-8-phenyl-7H-purine-2,6-dione

ethyl 2-methyl-4-(1,3-oxazol-5-yl)-1,4-dihydropyrimido[1,2-a]benzimidazole-3-carboxylate

2-(furan-2-yl)-N-(2-methoxyethyl)-[1,2,4]triazolo[1,5-a]quinoxalin-4-amine

N-[6-(3-fluorophenyl)-5-pyridin-4-ylpyridin-2-yl]acetamide

N-(4,6-diphenylpyrimidin-2-yl)propanamide

N-[5-bromo-6-(furan-2-yl)pyridin-2-yl]cyclopropanecarboxamide

7-methyl-3-(oxolan-2-ylmethyl)-8-phenyl-1-propylpurine-2,6-dione

N-[4,6-bis(2,3-dimethoxyphenyl)pyridin-2-yl]acetamide

2-(furan-2-yl)-4-(furan-3-ylmethoxy)-[1,2,4]triazolo[1,5-a]quinoxaline

N-(4-acetylphenyl)-2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]acetamide

N-[6-(3-fluorophenyl)-5-pyridin-4-ylpyridin-2-yl]cyclopropanecarboxamide

N-[4,6-bis(1,3-benzodioxol-5-yl)pyrimidin-2-yl]butanamide

N-[4,6-bis(2-methoxyphenyl)pyridin-2-yl]acetamide

1-ethyl-3,8-bis(thiophen-2-ylmethyl)-7H-purine-2,6-dione

N-[6-(2-fluorophenyl)-5-pyridin-4-ylpyridin-2-yl]cyclopropanecarboxamide

4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol

[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl N-(4-fluorophenyl)carbamate

6-(4-(2-(4-benzylpiperazin-1-yl)-2-oxoethoxy)phenyl)-7-hydroxy-1,3-dipropyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

N-[5-(3-fluoropyridin-4-yl)-6-(1,3-oxazol-2-yl)pyrazin-2-yl]cyclopropanecarboxamide

2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]-N-(1,2-oxazol-3-yl)acetamide

2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]-N-(4-fluorophenyl)acetamide

4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine

2-(1-Methyl-2-phenylethylamino)adenosine

N-[4,6-di(thiophen-3-yl)pyrimidin-2-yl]propanamide

N-(4-bromophenyl)-2-[4-[1-ethyl-3-(3-methoxypropyl)-2,6-dioxo-7H-purin-8-yl]phenoxy]acetamide

N-(4-bromophenyl)-2-[4-(7-hydroxy-2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide

1,3-dipropyl-8-cyclopentylxanthine

N-[6-(furan-2-yl)-5-pyridin-4-ylpyridin-2-yl]cyclopropanecarboxamide

N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-phenylacetamide

2-(furan-2-yl)-4-phenylmethoxy-[1,2,4]triazolo[1,5-a]quinoxaline

N-[6-(furan-2-yl)-5-pyridin-4-ylpyrazin-2-yl]acetamide

N-[2,6-bis(4-methoxyphenyl)pyrimidin-4-yl]acetamide

8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-dione

N-[2,6-bis(4-methoxyphenyl)pyrimidin-4-yl]-4-[4-[2-(tert-butylamino)-2-oxoethyl]piperazin-1-yl]-4-oxobutanamide

N-[5-(3-chloropyridin-4-yl)-6-(furan-2-yl)pyridin-2-yl]cyclopropanecarboxamide