Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
 Cell Line Info 
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT01252 , Serine/threonine-protein kinase PLK1
 Protein Info 
Gene Name PLK1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P53350
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017
 Cell Line Info 
 Protein ID: PT01252
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0858268
 Compound Info 
9-chloro-2-(3-(3-(dimethylamino)propyl)phenylamino)-5H-benzo[b]pyrimido[4,5-d]azepin-6(7H)-one
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C23H24ClN5O
  1
1
EC50 = 260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0917745
 Compound Info 
4-(9-chloro-6-oxo-6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepin-2-ylamino)-N-cyclopentylbenzamide
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C24H22ClN5O2
  1
1
EC50 = 630 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0896650
 Compound Info 
9-Chloro-2-(3,4-dimethoxyphenylamino)-5H-benzo[b]-pyrimido[4,5-d]azepin-6(7H)-one
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C20H17ClN4O3
  1
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0860166
 Compound Info 
9-Trifluoromethyl-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]-benzazepine-6-thione
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C24H25F3N6S
  1
1
EC50 = 29000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077179
 Compound Info 
9-chloro-2-[3-[3-(dimethylamino)propyl]-4-methoxyanilino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
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C24H26ClN5OS
  1
1
EC50 = 32000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071290
 Compound Info 
9-chloro-2-[[5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl]amino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
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C23H25ClN6S
  1
1
EC50 = 33000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071294
 Compound Info 
9-chloro-2-[3-[3-(dimethylamino)propyl]-4-fluoroanilino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
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C23H23ClFN5S
  1
1
EC50 = 38000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071288
 Compound Info 
9-chloro-2-[3-[3-(dimethylamino)propyl]anilino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
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C23H24ClN5S
  1
1
EC50 = 44000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0145317
 Compound Info 
9-chloro-2-[[5-[3-(dimethylamino)propyl]pyridin-3-yl]amino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
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C22H23ClN6S
  1
1
EC50 = 53000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071292
 Compound Info 
9-chloro-2-[5-[3-(dimethylamino)propyl]-2-methylanilino]-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
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C24H26ClN5S
  1
1
EC50 = 64000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS