| Compound ID |
Compound Name |
Compound Formula |
|
CP0396159
|
1-(6-chloroquinazolin-4-yl)-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C22H23ClN8O
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0474897
|
1-(6-fluoroquinazolin-4-yl)-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C22H23FN8O
|
1
|
| 1 |
EC50 = 126 nM
|
|
|
|
CP0544861
|
N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-1-(difluoromethyl)-1H-pyrazole-4-carboxamide
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|
C22H23ClN8O
|
1
|
| 1 |
EC50 = 241 nM
|
|
|
|
CP0411763
|
1-([1]benzothiolo[3,2-d]pyrimidin-4-yl)-3-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-triazole-3,5-diamine
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|
C24H24N8OS
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0423177
|
1-(2-methylquinazolin-4-yl)-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C23H26N8O
|
1
|
| 1 |
EC50 = 320 nM
|
|
|
|
CP0469674
|
1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C21H23ClN8OS
|
1
|
| 1 |
EC50 = 582 nM
|
|
|
|
CP0411762
|
1-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-triazole-3,5-diamine
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|
C21H26N8O
|
1
|
| 1 |
EC50 = 1005 nM
|
|
|
|
CP0411764
|
1-(6,7-dimethoxyquinazolin-4-yl)-N3-(4-(1-methylpiperidin-4-yl)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C24H28N8O2
|
1
|
| 1 |
EC50 = 1320 nM
|
|
|
|
CP0563230
|
1-(6,7-dimethoxyquinazolin-4-yl)-N3-(4-(1-methylpiperidin-3-yloxy)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C24H28N8O3
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0396158
|
[5-amino-3-[3-fluoro-4-(2-pyrrolidin-1-ylethoxy)anilino]-1,2,4-triazol-1-yl]-(4-morpholin-4-ylphenyl)methanone
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|
C25H30FN7O3
|
1
|
| 1 |
EC50 = 2750 nM
|
|
|
|
CP0476449
|
N3-(3-chloro-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(6,7-dimethoxyquinazolin-4-yl)-1H-1,2,4-triazole-3,5-diamine
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|
C24H27ClN8O3
|
1
|
| 1 |
EC50 = 4170 nM
|
|
|
|
CP0226098
|
1-(6,7-dimethoxyquinazolin-4-yl)-3-N-[4-(4-methylpiperazin-1-yl)phenyl]-1,2,4-triazole-3,5-diamine
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|
C23H27N9O2
|
1
|
| 1 |
EC50 = 4580 nM
|
|
|
|
CP0423179
|
1-(6,7-dimethoxyquinazolin-4-yl)-N3-(4-((S)-3-(dimethylamino) pyrrolidin-1-yl)phenyl)-1H-1,2,4-triazole-3,5-diamine
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|
C24H29N9O2
|
1
|
| 1 |
EC50 = 4760 nM
|
|
|
|
CP0423178
|
3-N-[4-(4-cyclohexylpiperazin-1-yl)-3-fluorophenyl]-1-(6,7-dimethoxyquinazolin-4-yl)-1,2,4-triazole-3,5-diamine
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|
C28H34FN9O2
|
1
|
| 1 |
EC50 = 5030 nM
|
|
|
|
CP0072335
|
3-N-[4-[4-(2-bicyclo[2.2.1]heptanyl)piperazin-1-yl]-3-chlorophenyl]-1-(6,7-dimethoxyquinazolin-4-yl)-1,2,4-triazole-3,5-diamine
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|
C29H34ClN9O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
