Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
 Cell Line Info 
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT00903 , C-C chemokine receptor type 5
 Protein Info 
Gene Name CCR5
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P51681
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017
 Cell Line Info 
 Protein ID: PT00903
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0510702
 Compound Info 
5-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4,6-dimethyl-2-N-propan-2-ylpyridine-2,5-dicarboxamide
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C35H48N6O3
  1
1
IC50 = 0.09 nM
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CP0036198
 Compound Info 
6-chloro-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C31H40ClN5O2
  1
1
IC50 = 0.2 nM
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CP0372492
 Compound Info 
6-fluoro-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C31H40FN5O2
  1
1
IC50 = 0.3 nM
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CP0476415
 Compound Info 
6-chloro-N-[(3R)-3-[4-[N-[(6-cyanopyridin-2-yl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C31H37ClN6O2
  1
1
IC50 = 0.3 nM
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CP0496095
 Compound Info 
6-cyano-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C32H40N6O2
  1
1
IC50 = 0.3 nM
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CP0524696
 Compound Info 
6-cyano-N-[(3R)-3-[4-[N-[(6-cyanopyridin-2-yl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C32H37N7O2
  1
1
IC50 = 0.3 nM
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CP0393708
 Compound Info 
6-chloro-N-[(3R)-3-[4-[4-(2-methoxyethoxy)-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C33H44ClN5O3
  1
1
IC50 = 0.6 nM
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CP0428242
 Compound Info 
N-[(3R)-3-[4-[N-[(6-cyanopyridin-2-yl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]-6-fluoro-2,4-dimethylpyridine-3-carboxamide
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C31H37FN6O2
  1
1
IC50 = 0.7 nM
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CP0431208
 Compound Info 
2-chloro-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
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C30H38ClN5O2
  1
1
IC50 = 0.7 nM
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CP0393450
 Compound Info 
6-cyano-N-[(3R)-3-[4-[4-(2-methoxyethoxy)-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C34H44N6O3
  1
1
IC50 = 0.8 nM
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CP0499370
 Compound Info 
N-[(3R)-3-[4-[4-(2-amino-2-oxoethoxy)-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-6-cyano-2,4-dimethylpyridine-3-carboxamide
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C33H41N7O3
  1
1
IC50 = 0.98 nM
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CP0492499
 Compound Info 
6-fluoro-N-[(3R)-3-[4-[4-(2-methoxyethoxy)-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C33H44FN5O3
  1
1
IC50 = 1.3 nM
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CP0452408
 Compound Info 
6-chloro-N-[(3R)-3-[4-[4-methoxy-N-(pyridin-3-ylmethyl)anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C30H38ClN5O2
  1
1
IC50 = 1.5 nM
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CP0523770
 Compound Info 
6-fluoro-N-[(3R)-3-[4-[4-methoxy-N-(pyridin-3-ylmethyl)anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C30H38FN5O2
  1
1
IC50 = 1.6 nM
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CP0523771
 Compound Info 
3,5-dichloro-N-[3-[4-[N-[(3-cyanophenyl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]pyridine-4-carboxamide
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C30H33Cl2N5O2
  1
1
IC50 = 2 nM
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CP0499449
 Compound Info 
N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C31H41N5O2
  1
1
IC50 = 2.4 nM
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CP0476257
 Compound Info 
3,5-dichloro-N-[3-[4-[N-[(3-cyanophenyl)methyl]-4-(trifluoromethyl)anilino]piperidin-1-yl]butyl]pyridine-4-carboxamide
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C30H30Cl2F3N5O
  1
1
IC50 = 3 nM
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CP0499450
 Compound Info 
3,5-dichloro-N-[3-[4-[N-[(3-cyanophenyl)methyl]-4-(trifluoromethoxy)anilino]piperidin-1-yl]butyl]pyridine-4-carboxamide
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C30H30Cl2F3N5O2
  1
1
IC50 = 3 nM
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CP0382661
 Compound Info 
N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-3,5-dimethylpyridine-4-carboxamide
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C31H41N5O2
  1
1
IC50 = 7 nM
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CP0400805
 Compound Info 
6-cyano-2,4-dimethyl-N-[(3R)-3-[4-[N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]pyridine-3-carboxamide
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C31H38N6O
  1
1
IC50 = 7 nM
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CP0476258
 Compound Info 
N-[3-[4-[4-bromo-N-[(3-cyanophenyl)methyl]anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C29H30BrCl2N5O
  1
1
IC50 = 8 nM
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CP0285119
 Compound Info 
N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
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C30H40N6O2
  1
1
IC50 = 10.9 nM
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CP0510699
 Compound Info 
4-[4-[benzyl-[1-[4-[(3,5-dichloropyridine-4-carbonyl)amino]butan-2-yl]piperidin-4-yl]amino]phenoxy]benzoic acid
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C35H36Cl2N4O4
  1
1
IC50 = 11 nM
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CP0533044
 Compound Info 
3,5-dichloro-N-[3-[4-[4-cyano-N-[(3-cyanophenyl)methyl]anilino]piperidin-1-yl]butyl]pyridine-4-carboxamide
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C30H30Cl2N6O
  1
1
IC50 = 12 nM
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CP0495962
 Compound Info 
6-chloro-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
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C30H38ClN5O2
  1
1
IC50 = 12.3 nM
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CP0433030
 Compound Info 
N-[3-[4-(N-benzyl-4-cyanoanilino)piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C29H31Cl2N5O
  1
1
IC50 = 19 nM
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CP0533043
 Compound Info 
N-[3-[4-[N-benzyl-4-(trifluoromethoxy)anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C29H31Cl2F3N4O2
  1
1
IC50 = 26 nM
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CP0495966
 Compound Info 
N-[3-[4-[4-bromo-N-[(3-chlorophenyl)methyl]anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C28H30BrCl3N4O
  1
1
IC50 = 30 nM
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CP0496055
 Compound Info 
N-[3-[4-[N-benzyl-4-(trifluoromethyl)anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C29H31Cl2F3N4O
  1
1
IC50 = 34 nM
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CP0395791
 Compound Info 
6-chloro-N-[(3S)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
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C31H40ClN5O2
  1
1
IC50 = 40 nM
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CP0463516
 Compound Info 
N-[3-[4-(N-benzyl-4-bromoanilino)piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C28H31BrCl2N4O
  1
1
IC50 = 49 nM
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CP0462147
 Compound Info 
N-[3-[4-(N-benzyl-4-methoxyanilino)piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C29H34Cl2N4O2
  1
1
IC50 = 50 nM
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CP0510700
 Compound Info 
methyl 4-[benzyl-[1-[4-[(3,5-dichloropyridine-4-carbonyl)amino]butan-2-yl]piperidin-4-yl]amino]benzoate
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C30H34Cl2N4O3
  1
1
IC50 = 90 nM
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CP0388035
 Compound Info 
N-[3-[4-[N-benzyl-4-(dimethylcarbamoyl)anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C31H37Cl2N5O2
  1
1
IC50 = 116 nM
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CP0533327
 Compound Info 
4,6-dimethyl-N-[(3R)-3-[4-[N-[(4-methylpyridin-3-yl)methyl]-4-methylsulfinylanilino]piperidin-1-yl]butyl]pyrimidine-5-carboxamide
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C30H40N6O2S
  1
1
IC50 = 130 nM
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CP0418787
 Compound Info 
N-[3-[4-[4-bromo-N-[(3-methoxyphenyl)methyl]anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
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C29H33BrCl2N4O2
  1
1
IC50 = 387 nM
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CP0433075
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[N-[(4-methylpyridin-3-yl)methyl]-4-morpholin-4-ylanilino]piperidin-1-yl]butyl]pyridine-3-carboxamide
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C34H45ClN6O2
  1
1
IC50 = 1586 nM
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