US9260440, 69

4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one

3,3-dimethyl-16-[2-(methylamino)ethyl]-6,7,16-triazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

US9260440, 68

US10501467, Example 49

US10501467, Example 46

US10501467, Example 58

US10501467, Example 9

US10501467, Example 59

US9260440, 41

US10501467, Example 40

US9260440, 11

US9260440, 18

US10501467, Example 65

US10501467, Example 15

US9260440, 2

US10501467, Example 31

US10501467, Example 57

US10501467, Example 8

11-fluoro-3-(1-hydroxycyclopropanecarbonyl)-3,6,7,16-tetrazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

US10501467, Example 2

US9260440, 62

US10501467, Example 55

US9260440, 27

US10501467, Example 16

US10501467, Example 28

US10501467, Example 45

US10501467, Example 7

US10501467, Example 47

US10501467, Example 42

US10501467, Example 26

US10501467, Example 43

US10501467, Example 34

3-cyclopropylsulfonyl-11-fluoro-3,6,7,16-tetrazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

6-Fluoro-2-((S)-pyrrolidine-2-carbonyl)-2,3,4,9-tetrahydro-1H-2,4,9,10-tetraaza-cyclohepta[def]fluoren-8-one

US10501467, Example 33

US9260440, 10

US10501467, Example 52

US10501467, Example 37

US10501467, Example 17

11-fluoro-3-(1-methylcyclopropanecarbonyl)-3,6,7,16-tetrazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

11-fluoro-3-(2,2,3,3-tetramethylcyclopropanecarbonyl)-3,6,7,16-tetrazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

3-(1-aminocyclopropanecarbonyl)-11-fluoro-3,6,7,16-tetrazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

US10501467, Example 35

11-fluoro-3-(1-phenylcyclopropanecarbonyl)-3,6,7,16-tetrazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),5,9(14),10,12-pentaen-8-one

US9260440, 12

US10501467, Example 38

US9260440, 34

US10501467, Example 19

14-fluoro-7-methyl-3,9,10,19-tetrazapentacyclo[14.2.1.03,7.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one

US9260440, 22

11-fluoro-4-hydroxy-3,3-dimethyl-6,7,16-triazatetracyclo[11.2.1.05,15.09,14]hexadeca-1(15),4,6,9(14),10,12-hexaene-2,8-dione

benzyl 10-oxo-2,11-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene-2-carboxylate

1-(2-(4-methoxyphenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

US10501467, Example 67

1-((S)-pyrrolidine-2-carbonyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

4-(2-oxo-2-(7-oxo-2,3,7,8,9,9a-hexahydro-1H-benzo[de][1,7]naphthyridin-1-yl)ethyl)benzonitrile

1-(2-(4-bromophenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

US10501467, Example 23

1-(2-(pyridin-2-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-phenylacetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(4-chlorobenzoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(piperidin-1-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(4-((diethylamino)methyl)benzoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(3-phenylpropanoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(pyridin-3-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(4-phenylpiperidin-1-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(3-(1-methyl-1H-pyrazol-4-yl)propanoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(4-phenylpiperazin-1-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(cyclopentanecarbonyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(4-(benzyloxy)phenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

US10501467, Example 29

1-(2-(4-chlorophenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(azetidine-3-carbonyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

N-benzyl-10-oxo-2,11-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene-2-carboxamide

1-benzoyl-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(2-chlorophenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

7-oxo-N-phenyl-2,3,7,8,9,9a-hexahydro-1H-benzo[de][1,7]naphthyridine-1-carboxamide

1-(2-(3-chlorophenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(3-methoxyphenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(3-methylbenzo[b]thiophen-2-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

phenyl 10-oxo-2,11-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene-2-carboxylate

US10501467, Example 36

US10501467, Example 32

1-(3-(1H-benzo[d]imidazol-1-yl)propanoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(2-methoxyphenyl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

US10501467, Example 39

1-(benzylsulfonyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-((2S)-1-(1-hydroxyethyl)pyrrolidine-2-carbonyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

N,N-dimethyl-4-oxo-4-(10-oxo-2,11-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-trien-2-yl)butanamide

1-(2-(4-methylthiazol-2-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(pyrrolidine-3-carbonyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(4-methylpiperazin-1-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

1-(2-(pyridin-4-yl)acetyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

5-oxo-5-(7-oxo-2,3,7,8,9,9a-hexahydro-1H-benzo[de][1,7]naphthyridin-1-yl)pentanoic acid

1-benzyl-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one

3,5-dimethyl-4,5,7-triazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3-trien-8-one

2-{4-[(dimethylamino)methyl]phenyl}-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one

5-methyl-3-(thiophen-2-yl)-4,5,7-triazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3-trien-8-one

3-methyl-1-phenyl-5a,6,7,8,9,9a-hexahydro-3H-pyrazolo[3,4-c]isoquinolin-5(4H)-one

2-[4-[5-(hydroxyamino)-5-oxopentoxy]phenyl]-1H-benzimidazole-4-carboxamide

2-[4-[4-(hydroxyamino)-4-oxobutoxy]phenyl]-1H-benzimidazole-4-carboxamide

US9073893, 22

2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide

2-[4-[6-(hydroxyamino)-6-oxohexoxy]phenyl]-1H-benzimidazole-4-carboxamide

US9073893, 18

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]piperazine-1-carboxamide

US9073893, 5

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]-1,4-diazepane-1-carboxamide

2-[4-[[4-[(E)-3-amino-3-oxoprop-1-enyl]phenyl]methoxy]phenyl]-1H-benzimidazole-4-carboxamide

3,5-dimethyl-4,5,7-triazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3-trien-8-one

2-[4-[(4-carbamoylphenyl)methoxy]phenyl]-1H-benzimidazole-4-carboxamide

2-[4-[7-(hydroxyamino)-7-oxoheptoxy]phenyl]-1H-benzimidazole-4-carboxamide

1-(2-aminoethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

US8877944, 99

US8877944, 49

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]-1-pyridin-4-ylpiperidine-4-carboxamide

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]pyridine-2-carboxamide

US9073893, 65

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]pyridine-3-carboxamide

2-[4-[8-(hydroxyamino)-8-oxooctoxy]phenyl]-1H-benzimidazole-4-carboxamide

US9073893, 9

1-methyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)pyrrolidine-3-carboxamide

4-methyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)-1,4-diazepane-1-carboxamide

2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxamide

1-methyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)piperidine-4-carboxamide

2-[4-[(4-carbamoylphenyl)methoxy]phenyl]indazole-7-carboxamide

US9073893, 62

1-(2-(isopropylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

1-(2-(cyclohexylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

US8877944, 105

3,5-dimethyl-11-thia-4,5,7-triazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3-trien-8-one

US9073893, 31

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]pyridine-4-carboxamide

2-(1-methylpiperidin-4-yl)-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)acetamide

US8877944, 29

US9073893, 6

2-[4-[5-(hydroxyamino)-5-oxopentoxy]phenyl]indazole-7-carboxamide

2-[4-[4-(hydroxyamino)-4-oxobutoxy]phenyl]indazole-7-carboxamide

5-methyl-3-phenyl-4,5,7-triazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3-trien-8-one

1-(2-(benzylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

US8877944, 31

5-methyl-3-phenyl-11-thia-4,5,7-triazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3-trien-8-one

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]-1-pyrimidin-2-ylpiperidine-4-carboxamide

2-[4-[7-(hydroxyamino)-7-oxoheptoxy]phenyl]indazole-7-carboxamide

1-(2-(diethylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

2-(dimethylamino)-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)acetamide

US9073893, 7

US9073893, 63

US9073893, 14

5-methyl-3-(thiophen-2-yl)-4,5,7-triazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3-trien-8-one

US8877944, 7

US9073893, 4

US9073893, 64

5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one

N-[2-(6-oxo-3,7,8,9-tetrahydropyrrolo[3,2-f]isoquinolin-1-yl)ethyl]piperidine-4-carboxamide

1-(2-(oxazol-4-ylmethylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

US9073893, 33

3-oxo-2-(3-piperidin-1-ylpropyl)-1H-isoindole-4-carboxamide

2-[4-[[4-[(E)-3-amino-3-oxoprop-1-enyl]phenyl]methoxy]phenyl]indazole-7-carboxamide

2-morpholino-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)acetamide

4-benzyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)-1,4-diazepane-1-carboxamide

US9073893, 3

US9073893, 66

US9073893, 2

2-[4-[8-(hydroxyamino)-8-oxooctoxy]phenyl]indazole-7-carboxamide

2-[4-[6-(hydroxyamino)-6-oxohexoxy]phenyl]indazole-7-carboxamide

1-(2-((1H-pyrazol-4-yl)methylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one

US9073893, 23

3-oxo-2-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-isoindole-4-carboxamide