Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT06381 , Aurora kinase A
Gene Name AURKA
Organism Mus musculus, Mouse
Protein Classification Kinase
Uniprot ID P97477
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013  Protein ID: PT06381
 
Compound ID Compound Name Compound Formula
CP0032546
4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-ylamino)-2-methoxybenzoic acid
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C27H20ClFN4O4
 2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
Ki = 0.3 nM
   TI
   LI
   LO
   TS
CP0017774
4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
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C25H15ClF2N4O2
 3
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 31 nM
   TI
   LI
   LO
   TS
3
Ki = 7 nM
   TI
   LI
   LO
   TS
CP0108599
4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
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C26H18ClFN4O3
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0385532
4-[[9-chloro-7-(2-fluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
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C25H16ClFN4O2
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0395997
9-chloro-7-(2-fluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-amine
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C18H12ClFN4
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS