Compound ID |
Compound Name |
Compound Formula |
CP0238111
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C21H22F3N5O3S
|
1
|
1 |
IC50 = 60 nM
|
|
|
CP0417920
|
1-(3-{[(2S)-2-aminopropanamido]methyl}phenyl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H24F3N5O3
|
1
|
1 |
IC50 = 60 nM
|
|
|
CP0538577
|
N-[(2-methoxyphenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C23H26F3N5O2
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0453810
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-N-benzyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C20H20F3N5O2S
|
1
|
1 |
IC50 = 220 nM
|
|
|
CP0467352
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-yl)-N-benzyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C20H20F3N5O2S
|
1
|
1 |
IC50 = 230 nM
|
|
|
CP0423665
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-N-[(2-methylphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C21H22F3N5O2S
|
1
|
1 |
IC50 = 260 nM
|
|
|
CP0467351
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-yl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C21H22F3N5O3S
|
1
|
1 |
IC50 = 300 nM
|
|
|
CP0479925
|
1-(3-((2-(methylamino)ethylamino)methyl)phenyl)-N-(naphthalen-1-ylmethyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C26H26F3N5O
|
1
|
1 |
IC50 = 320 nM
|
|
|
CP0423666
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-N-[(3-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C21H22F3N5O3S
|
1
|
1 |
IC50 = 370 nM
|
|
|
CP0400377
|
N-(2,3-dihydro-1,4-benzodioxin-5-ylmethyl)-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H26F3N5O3
|
1
|
1 |
IC50 = 710 nM
|
|
|
CP0535291
|
N-[(5-fluoro-2-methoxyphenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C23H25F4N5O2
|
1
|
1 |
IC50 = 710 nM
|
|
|
CP0453811
|
methyl 2-({[1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]formamido}methyl)benzoate
Show/Hide
|
C22H22F3N5O4S
|
1
|
1 |
IC50 = 770 nM
|
|
|
CP0462670
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-N-[(2-fluorophenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C20H19F4N5O2S
|
1
|
1 |
IC50 = 790 nM
|
|
|
CP0504601
|
N-[(2-ethoxyphenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H28F3N5O2
|
1
|
1 |
IC50 = 900 nM
|
|
|
CP0373511
|
1-(3-((2-aminoethylamino)methyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C22H24F3N5O2
|
1
|
1 |
IC50 = 1000 nM
|
|
|
CP0527167
|
N-[(2-ethylphenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H28F3N5O
|
1
|
1 |
IC50 = 1610 nM
|
|
|
CP0463717
|
N-[2-(1H-indol-3-yl)ethyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H27F3N6O
|
1
|
1 |
IC50 = 1800 nM
|
|
|
CP0502096
|
1-(4-{[(2S)-2-aminopropanamido]methyl}-1,3-thiazol-2-yl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C20H21F3N6O3S
|
1
|
1 |
IC50 = 2200 nM
|
|
|
CP0372953
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-yl)-N-[(2-fluorophenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C20H19F4N5O2S
|
1
|
1 |
IC50 = 2310 nM
|
|
|
CP0547533
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-yl)-N-{[2-(propan-2-yloxy)phenyl]methyl}-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H26F3N5O3S
|
1
|
1 |
IC50 = 2920 nM
|
|
|
CP0502097
|
1-(6-{[(2S)-2-aminopropanamido]methyl}pyridin-2-yl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C22H23F3N6O3
|
1
|
1 |
IC50 = 3050 nM
|
|
|
CP0896438
|
(S)-1-(5-((2-aminopropanamido)methyl)thiophen-2-yl)-N-(pyridin-2-ylmethyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C19H19F3N6O2S
|
1
|
1 |
IC50 = 3350 nM
|
|
|
CP0463718
|
N-[(2-methoxynaphthalen-1-yl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C27H28F3N5O2
|
1
|
1 |
IC50 = 3350 nM
|
|
|
CP0536411
|
N-(cyclohexylmethyl)-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C22H30F3N5O
|
1
|
1 |
IC50 = 3600 nM
|
|
|
CP0372892
|
1-(4-{[(2S)-2-aminopropanamido]methyl}pyridin-2-yl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C22H23F3N6O3
|
1
|
1 |
IC50 = 4200 nM
|
|
|
CP0535292
|
N-(1H-benzimidazol-2-ylmethyl)-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C23H24F3N7O
|
1
|
1 |
IC50 = 4300 nM
|
|
|
CP0502098
|
1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-yl)-3-(trifluoromethyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-1H-pyrazole-5-carboxamide
Show/Hide
|
C21H19F6N5O2S
|
1
|
1 |
IC50 = 4480 nM
|
|
|
CP0526348
|
(S)-1-(3-((2-aminopropanethioamido)methyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H24F3N5O2S
|
1
|
1 |
IC50 = 4500 nM
|
|
|
CP0526349
|
2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-N-[(1-methylbenzimidazol-2-yl)methyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H26F3N7O
|
1
|
1 |
IC50 = 4700 nM
|
|
|
CP0463719
|
1-(4-fluoro-3-((2-(methylamino)ethylamino)methyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H25F4N5O2
|
1
|
1 |
IC50 = 5600 nM
|
|
|
CP0496143
|
1-(3-((2-(methylamino)ethylamino)methyl)phenyl)-N-(2-(trifluoromethoxy)benzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H23F6N5O2
|
1
|
1 |
IC50 = 6500 nM
|
|
|
CP0415272
|
1-(3-((2-(ethylamino)ethylamino)methyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C24H28F3N5O2
|
1
|
1 |
IC50 = 7700 nM
|
|
|
CP0485284
|
1-(3-((2-(dimethylamino)ethylamino)methyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C24H28F3N5O2
|
1
|
1 |
IC50 = 7900 nM
|
|
|
CP0447507
|
N-[(2-methoxyphenyl)methyl]-2-[4-methyl-3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H28F3N5O2
|
1
|
1 |
IC50 = 7940 nM
|
|
|
CP0462669
|
1-(2-{[(2S)-2-aminopropanamido]methyl}-1-benzofuran-7-yl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C25H24F3N5O4
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0899698
|
1-(2-(((S)-2-aminopropanamido)methyl)isoindolin-4-yl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C25H27F3N6O3
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0485293
|
5-(2-methoxybenzyl)-8-((2-(methylamino)ethylamino)methyl)-2-(trifluoromethyl)pyrazolo[1,5-a]quinoxalin-4(5H)-one
Show/Hide
|
C23H24F3N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0506470
|
N-benzyl-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C22H24F3N5O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0527168
|
N-[(2-aminophenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C22H25F3N6O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0536410
|
1-(3-((2-(methylamino)ethylamino)methyl)phenyl)-N-(2-methylbenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H26F3N5O
|
1
|
1 |
IC50 = 13100 nM
|
|
|
CP0383682
|
(S)-1-(3-((2-hydroxypropanamido)methyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H23F3N4O4
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0383685
|
N-[(2-methoxyphenyl)methyl]-2-[3-[2-(methylamino)ethylcarbamoyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C23H24F3N5O3
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0463716
|
(S)-1-(3-(2-(2-aminopropanamido)ethyl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C24H26F3N5O3
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0479923
|
(S)-1-(3-(5-(1-aminoethyl)-1H-1,2,4-triazol-3-yl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H22F3N7O2
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0479926
|
N-[(2-methoxyphenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H25F6N5O2
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0490953
|
N-[(2-methoxyphenyl)methyl]-2-[3-[(pyrrolidin-3-ylamino)methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H26F3N5O2
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0501460
|
(S)-1-(3-(5-(1-aminoethyl)-1,2,4-oxadiazol-3-yl)phenyl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C23H21F3N6O3
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0479924
|
N-[(2-methoxyphenyl)methyl]-2-[3-[1-[2-(methylamino)ethylamino]ethyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H28F3N5O2
|
1
|
1 |
IC50 = 21000 nM
|
|
|