| Compound ID |
Compound Name |
Compound Formula |
|
CP0527909
|
6-amino-N-[3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenyl]pyridine-3-carboxamide
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|
C25H21N7O3
|
1
|
| 1 |
IC50 = 0.82 nM
|
|
|
|
CP0495099
|
3-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)pentan-3-ol
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0968902
|
1-(2-Amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-3-methylpent-1-yn-3-ol
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0130395
|
4-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-2-methylbut-3-yn-2-ol
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|
C20H20N4O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0545449
|
APILIMOD
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|
C23H26N6O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0568572
|
N-[(E)-(3-methylphenyl)methylideneamino]-7-morpholin-4-yl-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-5-amine
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|
C23H23N7O
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0564497
|
4-[3-(2-aminopyrimidin-4-yl)-1H-indol-5-yl]-2-methylbut-3-yn-2-ol
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|
C17H16N4O
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0576179
|
16-(2-methoxypropan-2-yl)-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-4-amine
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0545398
|
16-[3-(dimethylamino)prop-1-ynyl]-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-4-amine
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|
C20H21N5
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0495093
|
10-(4-fluorophenyl)-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine
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|
C20H15FN4
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0563004
|
16-(4-fluorophenyl)-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-4-amine
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|
C21H17FN4
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0527910
|
16-(2-pyridin-4-ylethynyl)-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-4-amine
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|
C22H17N5
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0570994
|
16-(1-methylpyrazol-4-yl)-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-4-amine
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|
C19H18N6
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0495095
|
10-(1-methylpyrazol-4-yl)-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine
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|
C18H16N6
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0568574
|
4-(4-amino-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-17-yl)-2-methylbut-3-yn-2-ol
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|
C21H22N4O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0545397
|
17-(2-cyclopropylethynyl)-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C21H20N4
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0495097
|
10-[2-(3-methylimidazol-4-yl)ethynyl]-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine
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|
C20H16N6
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0495094
|
N-[2-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)propan-2-yl]methanesulfonamide
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|
C19H23N5O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0561400
|
17-[2-(3-methylimidazol-4-yl)ethynyl]-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C22H20N6
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0577175
|
17-[3-(dimethylamino)prop-1-ynyl]-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C21H23N5
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0545395
|
17-(2-pyridin-4-ylethynyl)-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C23H19N5
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0573406
|
17-cyclopropyl-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C19H20N4
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
