Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT04672 , Diacylglycerol kinase zeta
Gene Name DGKZ
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q13574
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013  Protein ID: PT04672
 
Compound ID Compound Name Compound Formula
CP0414312
8-[(2S,5R)-4-[(2-fluorophenyl)-(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-5-methyl-6-oxo-1,5-naphthyridine-2-carbonitrile
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C29H27F2N5O
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0553976
8-[(2S,5R)-4-[bis(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-5-methyl-6-oxo-1,5-naphthyridine-2-carbonitrile
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C29H27F2N5O
 1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
CP0531467
8-[(3R)-4-[(4-chlorophenyl)-phenylmethyl]-3-methylpiperazin-1-yl]-5-methyl-6-oxo-1,5-naphthyridine-2,7-dicarbonitrile
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C29H25ClN6O
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0557646
8-[(3R)-4-[bis(4-chlorophenyl)methyl]-3-methylpiperazin-1-yl]-5-methyl-6-oxo-1,5-naphthyridine-2,7-dicarbonitrile
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C29H24Cl2N6O
 1
1
IC50 = 830 nM
   TI
   LI
   LO
   TS
CP0534225
8-[(3S)-4-[bis(4-fluorophenyl)methyl]-3-methylpiperazin-1-yl]-7-chloro-5-methyl-6-oxo-1,5-naphthyridine-2-carbonitrile
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C28H24ClF2N5O
 1
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0557647
8-[(2S,5R)-4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-2,5-dimethylpiperazin-1-yl]-5-methyl-6-oxo-1,5-naphthyridine-2-carbonitrile
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C24H23F2N5O3
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0552695
8-[(2R)-4-[bis(4-fluorophenyl)methyl]-2-ethylpiperazin-1-yl]-5-methyl-6-oxo-1,5-naphthyridine-2-carbonitrile
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C29H27F2N5O
 1
1
IC50 = 7000 nM
   TI
   LI
   LO
   TS