Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
 Cell Line Info 
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT02259 , Neuropeptide Y receptor type 1
 Protein Info 
Gene Name NPY1R
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25929
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013
 Cell Line Info 
 Protein ID: PT02259
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0160346
 Compound Info 
N'-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(oxan-4-yl)ethane-1,2-diamine
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C22H27Cl2N5O2
  1
1
Ki = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0498462
 Compound Info 
N'-[3-(2,6-dichloro-4-ethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(oxan-4-yl)ethane-1,2-diamine
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C23H29Cl2N5O2
  1
1
Ki = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0499747
 Compound Info 
N'-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(2-fluorocyclohexyl)ethane-1,2-diamine
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C23H28Cl2FN5O
  1
1
Ki = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504630
 Compound Info 
1-N-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-2-N-(oxan-4-yl)propane-1,2-diamine
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C23H29Cl2N5O2
  1
1
Ki = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0503222
 Compound Info 
N'-[3-(2,6-dichlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(oxan-4-yl)ethane-1,2-diamine
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C21H25Cl2N5O
  1
1
Ki = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436011
 Compound Info 
N'-[3-(2,6-dichloro-4-propoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(oxan-4-yl)ethane-1,2-diamine
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C24H31Cl2N5O2
  1
1
Ki = 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486649
 Compound Info 
N-cyclopentyl-N'-[2,5-dimethyl-3-(2,4,6-trimethylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]ethane-1,2-diamine
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C24H33N5
  1
1
Ki = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0482427
 Compound Info 
N'-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(2-fluoroethyl)ethane-1,2-diamine
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C19H22Cl2FN5O
  1
1
Ki = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486651
 Compound Info 
N'-[2,5-dimethyl-3-(2,4,6-trimethylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N-[2-(4-methoxyphenyl)ethyl]ethane-1,2-diamine
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C28H35N5O
  1
1
Ki = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504631
 Compound Info 
N-cyclopentyl-N'-[3-(2,6-dichlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]ethane-1,2-diamine
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C21H25Cl2N5
  1
1
Ki = 38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0503221
 Compound Info 
1-N-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-2-N-(oxan-4-yl)propane-1,2-diamine
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C24H31Cl2N5O2
  1
1
Ki = 141 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0499746
 Compound Info 
N'-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(2,2-difluoroethyl)ethane-1,2-diamine
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C19H21Cl2F2N5O
  1
1
Ki = 383 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0160562
 Compound Info 
N'-[2,5-dimethyl-3-(2,4,6-trimethylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]ethane-1,2-diamine
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C19H25N5
  1
1
Ki = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS