Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT01726 , Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Gene Name PDE1A
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P54750
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013  Protein ID: PT01726
 
Compound ID Compound Name Compound Formula
CP0013428
N-[(1S)-1-[3-fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl]-7-methoxy-2-oxo-1,3-dihydropyrido[2,3-b]pyrazine-4-carboxamide
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C19H18F4N4O5
 1
1
IC50 = 2497 nM
   TI
   LI
   LO
   TS
CP0000847
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
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C22H19N3O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0176508
[4-[3-(3-fluoro-4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C29H31FN4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0365459
[4-[5-tert-butyl-3-(3,5-difluoro-4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C26H32F2N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0444327
[4-[3-(4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C29H32N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0419692
N-(2-hydroxyethyl)-4-[3-(4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]benzamide
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C26H27N3O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0419693
[4-[5-tert-butyl-3-(2,3-difluoro-4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C26H32F2N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0109248
(2S,8R)-2-(5-bromothiophen-2-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
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C19H16BrN3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0109250
(2S,8R)-6-methyl-2-(5-methylthiophen-2-yl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
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C20H19N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0144390
(2S,8R)-2-(5-ethylfuran-2-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
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C21H21N3O3
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0157968
(10S,15S)-13-ethyl-10-(5-methylfuran-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C20H19N3O3
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0157969
(10S,15S)-13-ethyl-10-(5-ethylthiophen-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C21H21N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0164472
(10S,15R)-13-ethyl-10-(5-ethylthiophen-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C21H21N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0168902
(10S,15R)-13-ethyl-10-(5-ethylfuran-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C21H21N3O3
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0257911
(10S,15S)-13-ethyl-10-(5-ethylfuran-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C21H21N3O3
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0268684
(2S,8R)-2-(5-ethylthiophen-2-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
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C21H21N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0392073
(10S,15S)-13-butyl-10-(5-ethylthiophen-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C23H25N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0392075
(10R,15R)-13-ethyl-10-(5-ethylfuran-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C21H21N3O3
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0392491
(2R,8S)-2-(5-ethylthiophen-2-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
   Show/Hide
C21H21N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0432292
(10S,15R)-13-butyl-10-(5-ethylthiophen-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C23H25N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0440103
(10S,15S)-13-ethyl-10-(3-methylthiophen-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
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C20H19N3O2S
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS