| Compound ID |
Compound Name |
Compound Formula |
|
CP0181154
|
[(2S)-1-[[2-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]-1,3-oxazol-5-yl]oxy]propan-2-yl]urea
Show/Hide
|
C23H25N3O5
|
1
|
| 1 |
IC50 = 0.58 nM
|
|
|
|
CP0123444
|
N-[(2S)-1-[[2-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]-1,3-oxazol-5-yl]oxy]propan-2-yl]acetamide
Show/Hide
|
C24H26N2O5
|
1
|
| 1 |
IC50 = 0.96 nM
|
|
|
|
CP0228922
|
N-[(2S)-1-[[2-[6-[3-(cyclopropylmethoxy)phenoxy]pyridin-3-yl]-1,3-oxazol-5-yl]oxy]propan-2-yl]acetamide
Show/Hide
|
C23H25N3O5
|
1
|
| 1 |
IC50 = 0.96 nM
|
|
|
|
CP0565779
|
1'-[2-(4-aminophenyl)quinoline-4-carbonyl]-2-tert-butylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C30H31N5O3
|
1
|
| 1 |
IC50 = 1.29 nM
|
|
|
|
CP0202144
|
N-[1-[2-[6-[3-(cyclopropylmethoxy)phenoxy]pyridin-3-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C26H25N3O4
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0486323
|
2-tert-butyl-1'-[2-(4-methylphenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C31H32N4O3
|
1
|
| 1 |
IC50 = 2.22 nM
|
|
|
|
CP0533420
|
2-tert-butyl-1'-[2-[4-(dimethylamino)phenyl]quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C32H35N5O3
|
1
|
| 1 |
IC50 = 2.72 nM
|
|
|
|
CP0533419
|
2-tert-butyl-1'-[2-(4-methoxyphenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C31H32N4O4
|
1
|
| 1 |
IC50 = 3.18 nM
|
|
|
|
CP0514620
|
US8993586, 109
Show/Hide
|
C28H34N6O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0484345
|
2-tert-butyl-1'-[2-(3,4-dimethoxyphenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C32H34N4O5
|
1
|
| 1 |
IC50 = 3.57 nM
|
|
|
|
CP0058587
|
2-[1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acid
Show/Hide
|
C28H31N3O8S
|
1
|
| 1 |
IC50 = 4.34 nM
|
|
|
|
CP0181153
|
N-[4-[2-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]-1,3-oxazol-5-yl]butan-2-yl]acetamide
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0123442
|
N-[1-[2-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C27H26N2O4
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0173137
|
2-tert-butyl-1'-[2-(methylamino)quinoline-7-carbonyl]spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0253206
|
2-tert-butyl-1'-[2-(propylamino)quinoline-7-carbonyl]spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0422952
|
1'-[2-(4-bromophenyl)quinoline-4-carbonyl]-2-tert-butylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C30H29BrN4O3
|
1
|
| 1 |
IC50 = 5.67 nM
|
|
|
|
CP0442015
|
US8993586, 70
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0222214
|
N-[(2S)-1-[[2-[5-[3-(cyclopropylmethoxy)phenoxy]pyridin-2-yl]-1,3-oxazol-5-yl]oxy]propan-2-yl]acetamide
Show/Hide
|
C23H25N3O5
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0548206
|
2-tert-butyl-1'-(2-phenylquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C30H30N4O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0486321
|
2-tert-butyl-1'-[2-(4-chlorophenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C30H29ClN4O3
|
1
|
| 1 |
IC50 = 6.09 nM
|
|
|
|
CP0443695
|
US8993586, 107
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0556052
|
US8993586, 124
Show/Hide
|
C26H29F3N6O2
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0520559
|
US8993586, 45
Show/Hide
|
C24H32N6O2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0181152
|
N-[1-[2-[5-[3-(cyclopropylmethoxy)phenoxy]pyridin-2-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C26H25N3O4
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0101166
|
2-tert-butyl-1'-[2-(dimethylamino)quinoline-7-carbonyl]spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0488767
|
US8993586, 56
Show/Hide
|
C25H31N5O3
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0098313
|
N-[1-[2-[6-[3-(cyclopropylmethoxy)phenoxy]pyridin-3-yl]-1,3-benzothiazol-5-yl]ethyl]acetamide
Show/Hide
|
C26H25N3O3S
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0488759
|
US8993586, 106
Show/Hide
|
C27H32N6O2
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0555382
|
US8993586, 62
Show/Hide
|
C23H27ClN6O2
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0488765
|
US8993586, 49
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0468391
|
US8993586, 112
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0443697
|
US8993586, 125
Show/Hide
|
C27H32F2N6O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0563802
|
2-tert-butyl-1'-[2-(4-fluorophenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C30H29FN4O3
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0512489
|
2-tert-butyl-1'-(2-pyridin-4-ylquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C29H29N5O3
|
1
|
| 1 |
IC50 = 11.31 nM
|
|
|
|
CP0565149
|
2-tert-butyl-1'-(2-pyridin-2-ylquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C29H29N5O3
|
1
|
| 1 |
IC50 = 13.84 nM
|
|
|
|
CP0155906
|
2-tert-butyl-1'-(1-methoxyisoquinoline-7-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0468390
|
US8993586, 108
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0538780
|
US8993586, 51
Show/Hide
|
C26H31N5O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0558224
|
N-[1-[4-[[4-[3-(cyclopropylmethoxy)phenoxy]-2,6-difluorophenyl]methoxy]phenyl]ethyl]acetamide
Show/Hide
|
C27H27F2NO4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0488757
|
US8993586, 87
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0488768
|
US8993586, 66
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0529259
|
US8993586, 118
Show/Hide
|
C28H34N6O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0550231
|
US8993586, 121
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0329551
|
N-[1-[6-[[4-[3-(cyclopropylmethoxy)phenoxy]-2,6-difluorophenyl]methoxy]pyridin-3-yl]ethyl]acetamide
Show/Hide
|
C26H26F2N2O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0546036
|
N-[1-[4-[4-(4-propoxyphenoxy)phenyl]phenyl]ethyl]acetamide
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0068918
|
2-tert-butyl-1'-(1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 17.28 nM
|
|
|
|
CP0101168
|
2-tert-butyl-1'-(3-chloro-1H-indole-6-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C23H26ClN5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0488770
|
US8993586, 74
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0087724
|
2-tert-butyl-1'-(3-chloro-1H-pyrrolo[3,2-b]pyridine-6-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C22H25ClN6O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0173125
|
2-tert-butyl-1'-(2-methoxyquinoline-7-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0451906
|
US8993586, 116
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0173136
|
2-tert-butyl-1'-[1-(methylamino)isoquinoline-7-carbonyl]spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0443690
|
US8993586, 47
Show/Hide
|
C24H32N6O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0557560
|
US8993586, 54
Show/Hide
|
C23H27N7O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0087725
|
2-tert-butyl-1'-(3-chloro-2H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C22H25ClN6O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0443694
|
US8993586, 99
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0415363
|
N-[1-[2-[3-[3-(cyclopropylmethoxy)phenoxy]azetidin-1-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0459871
|
US8993586, 119
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0443886
|
1'-(3,7-dimethyl-2H-indazole-5-carbonyl)-1-propan-2-ylspiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C23H28N6O2
|
1
|
| 1 |
IC50 = 24.2 nM
|
|
|
|
CP0574808
|
US8993586, 44
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0098314
|
N-[1-[2-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]-1-benzothiophen-5-yl]ethyl]acetamide
Show/Hide
|
C28H27NO3S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0087723
|
US8993586, 8
Show/Hide
|
C24H30N6O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0248909
|
2-tert-butyl-1'-(3-chloro-1H-indole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C23H26ClN5O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0545658
|
US8993586, 111
Show/Hide
|
C27H34N6O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0488769
|
US8993586, 72
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0442014
|
US8993586, 43
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0549181
|
US8993586, 115
Show/Hide
|
C27H32N6O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0442000
|
US8993586, 50
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0551110
|
US8993586, 48
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0516877
|
N-[1-[6-[[4-[3-(cyclopropylmethoxy)phenoxy]-2,6-difluorophenyl]methoxy]pyridazin-3-yl]ethyl]acetamide
Show/Hide
|
C25H25F2N3O4
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0431135
|
2-tert-butyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0557282
|
US8993586, 29
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0457100
|
US8993586, 12
Show/Hide
|
C22H28N6O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0520557
|
US8993586, 46
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0570059
|
N-[1-[5-[[4-[3-(cyclopropylmethoxy)phenoxy]-2,6-difluorophenyl]methoxy]pyridin-2-yl]ethyl]acetamide
Show/Hide
|
C26H26F2N2O4
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0555559
|
N-[1-[4-[4-[3-(cyclopropylmethoxy)phenoxy]phenoxy]phenyl]ethyl]acetamide
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0441996
|
US8993586, 4
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0515554
|
US8993586, 60
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0450841
|
US8993586, 81
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0518560
|
US8993586, 120
Show/Hide
|
C27H34N6O3
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0530611
|
US8993586, 53
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0536240
|
US8993586, 73
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0087726
|
2-cyclobutyl-1'-(3,7-dimethyl-2H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0555557
|
N-[1-[4-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]phenyl]ethyl]acetamide
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0520556
|
US8993586, 7
Show/Hide
|
C23H28N6O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0538756
|
US8993586, 100
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0565636
|
US8993586, 96
Show/Hide
|
C22H25ClN6O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0515558
|
US8993586, 93
Show/Hide
|
C23H29N7O2
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0488763
|
US8993586, 36
Show/Hide
|
C25H29N5O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0519651
|
US8993586, 42
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0546037
|
N-[1-[4-[[4-[3-(cyclopropylmethoxy)phenoxy]-2-fluorophenyl]methoxy]phenyl]ethyl]acetamide
Show/Hide
|
C27H28FNO4
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0488762
|
US8993586, 17
Show/Hide
|
C26H30N4O4
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0537005
|
US8993586, 103
Show/Hide
|
C24H26ClN5O2
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0101164
|
2-tert-butyl-1'-[3-(trifluoromethyl)-2H-indazole-5-carbonyl]spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C23H25F3N6O2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0106316
|
2-tert-butyl-1'-(3-methoxyisoquinoline-6-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0451907
|
US8993586, 123
Show/Hide
|
C28H36N6O2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0516888
|
US8993586, 75
Show/Hide
|
C23H29N7O2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0426584
|
US8993586, 77
Show/Hide
|
C22H27N7O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0555617
|
US8993586, 11
Show/Hide
|
C21H25ClN6O2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0573601
|
US8993586, 52
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0551052
|
US8993586, 104
Show/Hide
|
C24H26ClN5O2
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0552431
|
N-[1-[5-[[4-[3-(cyclopropylmethoxy)phenoxy]-2,6-difluorophenyl]methoxy]pyrazin-2-yl]ethyl]acetamide
Show/Hide
|
C25H25F2N3O4
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0572199
|
N-[1-[4-[4-[4-(2-methoxyethyl)phenoxy]phenyl]phenyl]ethyl]acetamide
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0538781
|
US8993586, 61
Show/Hide
|
C22H27N7O2
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0443682
|
US8993586, 30
Show/Hide
|
C24H27N5O3
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0519654
|
US8993586, 95
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0563850
|
US8993586, 34
Show/Hide
|
C21H25ClN6O2
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0488761
|
US8993586, 16
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0516876
|
N-[1-[4-[4-(3-butoxyphenoxy)phenyl]phenyl]ethyl]acetamide
Show/Hide
|
C26H29NO3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0519649
|
US8993586, 26
Show/Hide
|
C24H27N5O3
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0520560
|
US8993586, 59
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0516767
|
US8993586, 94
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0558222
|
N-[1-[4-[4-[3-(2-methoxyethyl)phenoxy]phenyl]phenyl]ethyl]acetamide
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0551108
|
US8993586, 14
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0202145
|
N-[1-[3-[[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]methoxy]phenyl]ethyl]acetamide
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0556044
|
US8993586, 58
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 149 nM
|
|
|
|
CP0450163
|
US8993586, 32
Show/Hide
|
C21H25ClN6O2
|
1
|
| 1 |
IC50 = 154 nM
|
|
|
|
CP0556476
|
US8993586, 78
Show/Hide
|
C23H25F3N6O2
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
|
CP0536238
|
US8993586, 28
Show/Hide
|
C24H27N5O3
|
1
|
| 1 |
IC50 = 158 nM
|
|
|
|
CP0538782
|
US8993586, 63
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0556464
|
US8993586, 101
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0442916
|
US8993586, 83
Show/Hide
|
C23H25F3N6O2
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0519650
|
US8993586, 41
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0424209
|
6-(4-aminophenyl)-N-(6-fluoro-1H-indazol-5-yl)-1-propan-2-ylpyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C24H21FN6O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0556039
|
US8993586, 31
Show/Hide
|
C21H25ClN6O2
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0520561
|
US8993586, 69
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0450843
|
US8993586, 84
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0519653
|
US8993586, 90
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 209 nM
|
|
|
|
CP0414109
|
N-[1-[2-[3-(3-butoxyphenoxy)azetidin-1-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C24H29N3O4
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0458134
|
6-(4-aminophenyl)-N-(1H-indazol-5-yl)-1-propan-2-ylpyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C24H22N6O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0553825
|
US8993586, 79
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 216 nM
|
|
|
|
CP0556029
|
US8993586, 97
Show/Hide
|
C21H25N7O2
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0471101
|
N-[1-[2-[3-(3-pentylphenoxy)azetidin-1-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0546035
|
N-[1-[4-[[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]methoxy]phenyl]ethyl]acetamide
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0515556
|
US8993586, 68
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
|
CP0556463
|
US8993586, 5
Show/Hide
|
C21H24N6O2
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0436809
|
N-[1-[2-[4-[3-(cyclopropylmethoxy)phenoxy]piperidin-1-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
Show/Hide
|
C26H31N3O4
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0231723
|
CHEMBL1818291
Show/Hide
|
C30H38N4O3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0488758
|
US8993586, 91
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0222213
|
N-[(2R)-1-[[2-[4-[3-(cyclopropylmethoxy)phenoxy]phenyl]-1,3-oxazol-5-yl]oxy]propan-2-yl]acetamide
Show/Hide
|
C24H26N2O5
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0529260
|
US8993586, 92
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0521292
|
US8993586, 15
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 251 nM
|
|
|
|
CP0515555
|
US8993586, 65
Show/Hide
|
C22H27N7O2
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
|
CP0531830
|
US8993586, 25
Show/Hide
|
C22H25N7O2
|
1
|
| 1 |
IC50 = 259 nM
|
|
|
|
CP0450255
|
US8993586, 6
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0520706
|
US8993586, 27
Show/Hide
|
C22H27N7O3
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0556040
|
US8993586, 37
Show/Hide
|
C22H29N7O2
|
1
|
| 1 |
IC50 = 302 nM
|
|
|
|
CP0441998
|
US8993586, 39
Show/Hide
|
C21H26N6O2
|
1
|
| 1 |
IC50 = 329 nM
|
|
|
|
CP0468392
|
US8993586, 117
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 332 nM
|
|
|
|
CP0470288
|
US8993586, 20
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
IC50 = 336 nM
|
|
|
|
CP0551051
|
US8993586, 89
Show/Hide
|
C23H29N7O2
|
1
|
| 1 |
IC50 = 343 nM
|
|
|
|
CP0488764
|
US8993586, 38
Show/Hide
|
C24H28N6O2
|
1
|
| 1 |
IC50 = 364 nM
|
|
|
|
CP0515545
|
US8993586, 10
Show/Hide
|
C21H26N6O2
|
1
|
| 1 |
IC50 = 403 nM
|
|
|
|
CP0512748
|
US8993586, 1
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 417 nM
|
|
|
|
CP0443688
|
US8993586, 35
Show/Hide
|
C21H27N7O2
|
1
|
| 1 |
IC50 = 487 nM
|
|
|
|
CP0446296
|
US8993586, 122
Show/Hide
|
C27H32N6O3
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0515559
|
US8993586, 113
Show/Hide
|
C27H32N6O3
|
1
|
| 1 |
IC50 = 507 nM
|
|
|
|
CP0443686
|
US8993586, 33
Show/Hide
|
C21H28N8O2
|
1
|
| 1 |
IC50 = 523 nM
|
|
|
|
CP0415607
|
8-(2-phenyl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C29H25F3N4O2
|
1
|
| 1 |
IC50 = 527 nM
|
|
|
|
CP0556038
|
US8993586, 21
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
IC50 = 619 nM
|
|
|
|
CP0443680
|
US8993586, 23
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
IC50 = 621 nM
|
|
|
|
CP0515544
|
US8993586, 9
Show/Hide
|
C21H24N6O2
|
1
|
| 1 |
IC50 = 648 nM
|
|
|
|
CP0520558
|
US8993586, 40
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 656 nM
|
|
|
|
CP0572409
|
US8993586, 18
Show/Hide
|
C21H24N6O2
|
1
|
| 1 |
IC50 = 657 nM
|
|
|
|
CP0443681
|
US8993586, 24
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
IC50 = 688 nM
|
|
|
|
CP0508685
|
tert-butyl N-[[4-[[[2-[4-(2-aminoethyl)piperidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C30H45N5O3
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0516875
|
N-[1-[4-[[6-[3-(cyclopropylmethoxy)phenoxy]pyridin-3-yl]methoxy]phenyl]ethyl]acetamide
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0424204
|
N-(1H-indazol-5-yl)-1-methyl-6-phenylpyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C22H17N5O
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0231724
|
tert-butyl N-[[4-[[[2-[4-[2-(3-hydroxyazetidin-1-yl)ethyl]piperidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C33H49N5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0300505
|
2,2-dimethylpropyl N-[[4-[[[2-[4-[2-(dimethylamino)ethyl]piperidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C33H51N5O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0424205
|
1-ethyl-N-(1H-indazol-5-yl)-6-phenylpyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C23H19N5O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0389967
|
8-[2-(furan-2-yl)-3H-benzimidazole-5-carbonyl]-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C27H23F3N4O3
|
1
|
| 1 |
IC50 = 1054 nM
|
|
|
|
CP0504895
|
tert-butyl N-[[4-[[(2-pyridin-4-ylquinoline-4-carbonyl)amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C28H34N4O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0389966
|
8-[2-(4-propan-2-ylphenyl)-3H-benzimidazole-5-carbonyl]-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C32H31F3N4O2
|
1
|
| 1 |
IC50 = 1147 nM
|
|
|
|
CP0140948
|
tert-butyl N-[[4-[[[2-[4-[2-(dimethylamino)ethyl]piperidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C32H49N5O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0555558
|
N-[1-[4-[[5-[3-(cyclopropylmethoxy)phenoxy]pyridin-2-yl]methoxy]phenyl]ethyl]acetamide
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0492675
|
8-(7-methyl-1H-indazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C24H23F3N4O2
|
1
|
| 1 |
IC50 = 1202 nM
|
|
|
|
CP0519648
|
US8993586, 22
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
IC50 = 1250 nM
|
|
|
|
CP0501695
|
tert-butyl N-[[4-[[[2-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C30H42N6O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0577786
|
US8993586, 67
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 1340 nM
|
|
|
|
CP0516107
|
US8993586, 19
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
IC50 = 1480 nM
|
|
|
|
CP0470757
|
N-(1H-indazol-5-yl)-6-phenyl-1-propan-2-ylpyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C24H21N5O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0415606
|
8-(7-methyl-2-propyl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C27H29F3N4O2
|
1
|
| 1 |
IC50 = 1687 nM
|
|
|
|
CP0452481
|
tert-butyl N-[[4-[[[2-[4-(aminomethyl)phenyl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
|
C30H38N4O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0396625
|
8-(6,7,8,9-tetrahydro-5H-carbazole-3-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C28H28F3N3O2
|
1
|
| 1 |
IC50 = 1948 nM
|
|
|
|
CP0539234
|
2-methyl-4-[8-(7-methyl-1H-indazole-5-carbonyl)-3-oxo-2,8-diazaspiro[4.5]decan-2-yl]benzonitrile
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
IC50 = 2011 nM
|
|
|
|
CP0470286
|
US8993586, 13
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 2040 nM
|
|
|
|
CP0415609
|
8-(2-methyl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C24H23F3N4O2
|
1
|
| 1 |
IC50 = 2221 nM
|
|
|
|
CP0415608
|
methyl 4-[8-(7-methyl-1H-indazole-5-carbonyl)-3-oxo-2,8-diazaspiro[4.5]decan-2-yl]benzoate
Show/Hide
|
C25H26N4O4
|
1
|
| 1 |
IC50 = 2241 nM
|
|
|
|
CP0389897
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CHEMBL1818295
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C30H44N4O4
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1
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| 1 |
IC50 = 2300 nM
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CP0452480
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CHEMBL1818195
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C26H33N5O3
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1
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| 1 |
IC50 = 2300 nM
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CP0492676
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8-(2-pyridin-4-yl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
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C28H24F3N5O2
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1
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| 1 |
IC50 = 2649 nM
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CP0432398
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4-[8-(7-methyl-1H-indazole-5-carbonyl)-3-oxo-2,8-diazaspiro[4.5]decan-2-yl]benzoic acid
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C24H24N4O4
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1
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| 1 |
IC50 = 2792 nM
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CP0431231
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4-[4-[[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]cyclohexyl]methylcarbamoyl]quinolin-2-yl]benzoic acid
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C30H35N3O5
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1
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| 1 |
IC50 = 2900 nM
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CP0396623
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3-fluoro-4-[8-(7-methyl-1H-indazole-5-carbonyl)-3-oxo-2,8-diazaspiro[4.5]decan-2-yl]benzonitrile
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C24H22FN5O2
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1
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| 1 |
IC50 = 3559 nM
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CP0488760
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US8993586, 3
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C22H26N6O2
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1
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| 1 |
IC50 = 3920 nM
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CP0432396
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4-[8-(7-methyl-1H-indazole-5-carbonyl)-3-oxo-2,8-diazaspiro[4.5]decan-2-yl]benzonitrile
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C24H23N5O2
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1
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| 1 |
IC50 = 3990 nM
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CP0492677
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8-(1,2,3,4-tetrahydrocyclopenta[b]indole-7-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
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C27H26F3N3O2
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1
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| 1 |
IC50 = 4265 nM
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CP0472560
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tert-butyl N-[[4-[[[2-[4-(aminomethyl)piperidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
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C29H43N5O3
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1
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| 1 |
IC50 = 4300 nM
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CP0456081
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tert-butyl N-[[4-[[[2-[3-[2-(dimethylamino)ethoxy]azetidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
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C30H45N5O4
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1
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| 1 |
IC50 = 4500 nM
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CP0396624
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8-(1H-indazole-6-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
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C23H21F3N4O2
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1
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| 1 |
IC50 = 4726 nM
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CP0926226
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US8993586, 114
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C26H32N6O2
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1
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| 1 |
IC50 = 4820 nM
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CP0415610
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8-(quinoline-7-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
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C25H22F3N3O2
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1
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| 1 |
IC50 = 4923 nM
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CP0558684
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8-(1H-indole-6-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
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C24H22F3N3O2
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1
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| 1 |
IC50 = 4955 nM
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CP0143090
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CHEMBL1818294
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C31H48N6O3
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1
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| 1 |
IC50 = 5300 nM
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CP0431232
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oxan-4-yl N-[[4-[[[2-[4-[2-(dimethylamino)ethyl]piperidin-1-yl]quinoline-4-carbonyl]amino]methyl]cyclohexyl]methyl]carbamate
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C33H49N5O4
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1
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| 1 |
IC50 = 6300 nM
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CP0456078
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tert-butyl N-[[4-[[(2-phenylpyridine-4-carbonyl)amino]methyl]cyclohexyl]methyl]carbamate
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C25H33N3O3
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1
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| 1 |
IC50 = 6600 nM
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CP0426161
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CHEMBL1818301
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C30H45N5O3
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1
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| 1 |
IC50 = 8000 nM
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CP0506996
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tert-butyl N-[[4-[[(2-methyl-6-phenylpyridine-4-carbonyl)amino]methyl]cyclohexyl]methyl]carbamate
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C26H35N3O3
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1
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| 1 |
IC50 = 8300 nM
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CP0456082
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CHEMBL1817676
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C32H49N5O3
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1
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| 1 |
IC50 = 9900 nM
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CP0460202
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CHEMBL1818192
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C23H30ClN3O3
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1
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| 1 |
IC50 = 10000 nM
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CP0415362
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N-[1-[2-[3-(3-methylphenoxy)azetidin-1-yl]-1,3-benzoxazol-6-yl]ethyl]acetamide
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C21H23N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0389902
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tert-butyl N-[[4-[[(2-piperazin-1-ylquinoline-4-carbonyl)amino]methyl]cyclohexyl]methyl]carbamate
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C27H39N5O3
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1
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| 1 |
IC50 = 13000 nM
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CP0422953
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2-tert-butyl-1'-[2-(4-methylpiperazin-1-yl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C29H36N6O3
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1
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| 1 |
IC50 > 20 nM
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CP0484347
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2-tert-butyl-1'-(2-propan-2-yloxyquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C27H32N4O4
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1
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| 1 |
IC50 > 20 nM
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CP0533416
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2-tert-butyl-1'-(2-chloroquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C24H25ClN4O3
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1
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| 1 |
IC50 > 20 nM
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CP0533418
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2-tert-butyl-1'-(2-piperazin-1-ylquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C28H34N6O3
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1
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| 1 |
IC50 > 20 nM
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CP0553284
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2-tert-butyl-1'-(2-methylquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C25H28N4O3
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1
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| 1 |
IC50 > 20 nM
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CP0556004
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2-tert-butyl-1'-(2-morpholin-4-ylquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C28H33N5O4
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1
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| 1 |
IC50 > 20 nM
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CP0422950
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2-tert-butyl-1'-[2-(2-chlorophenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C30H29ClN4O3
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1
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| 1 |
IC50 > 100 nM
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CP0484346
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2-tert-butyl-1'-(2-ethoxyquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
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C26H30N4O4
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1
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| 1 |
IC50 > 100 nM
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CP0538098
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2-tert-butyl-1'-[2-(2-methylphenyl)quinoline-4-carbonyl]spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
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C31H32N4O3
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1
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| 1 |
IC50 > 100 nM
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CP0551706
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2-tert-butyl-1'-(2-methoxyquinoline-4-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
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C25H28N4O4
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1
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| 1 |
IC50 > 100 nM
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CP0432394
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8-(quinoline-6-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
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C25H22F3N3O2
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1
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| 1 |
IC50 > 5000 nM
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CP0539235
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8-(1H-indole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
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C24H22F3N3O2
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1
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| 1 |
IC50 > 5000 nM
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CP0539236
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8-(quinoline-3-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
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C25H22F3N3O2
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1
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| 1 |
IC50 > 5000 nM
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CP0873191
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N-(1H-indazol-5-yl)-6-phenyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C21H15N5O
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1
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| 1 |
IC50 <= 10000 nM
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