4-[(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-1,3-dioxo-1,2,3,4-tetra-hydroisoquinolin-6-yl]benzaldehyde

N-[(4Z)-1,3-Dioxo-4-({[4-piperidin-1-ylmethyl]phenyl}amino)-methylene]-1,2,3,4-tetrahydroisoquinolin-6-yl]acetamide

(4Z)-4-({[4-(Piperidin-1-ylmethyl)phenyl]amino}methylene)-isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Iodo-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(Morpholin-4-ylmethyl)phenyl]amino}methylene)-isoquinoline-1,3(2H,4H)-dione

(4Z)-1, 3-Dioxo-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}-methylene)-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile

(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)isoquinoline 1,3(2H,4H)-dione

(4Z)-4-{[(4-Morpholin-4-ylphenyl)amino]methylene}isoquinoline-1,3(2H,4H)-dione

(4Z)-N,N-Dimethyl-1,3-dioxo-4-({[4-(piperidinylmethyl)phenyl]-amino}methylene)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide

(4Z)-N,N-Dimethyl-4-({[4-(4-methylpiperazin-1-yl)phenyl]-amino}methylene)-1,3-dioxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamide

(4Z)-7-Bromo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

6-(phenylamino)-4-((4-(piperidin-1-ylmethyl)phenylamino)methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Piperidin-1-yl-4-({[4-(methylpiperazin-1-yl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Nitro-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Nitro-4-{[(4-piperidin-1-ylmethyl)phenyl]amino}methyleneisoquinoline-1,3(2H,4H)-dione

6-bromo-4-((4-(piperidin-1-ylmethyl)phenylamino)methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-(1H-pyrrol-1-yl)isoquinoline-1,3(2H,4H)-dione

N-[(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-6-yl]acetamide

(4Z)-6-Bromo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(4-Hydroxyphenyl)-4-({[4-piperidin-1-ylmethyl]phenyl}-amino)methylene)}isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Iodo-4-[({4-[(2S,5R)-2,4,5-trimethylpiperazin-1-yl]phenyl}amino)methylene]-isoquinoline-1,3(2H,4H)-dione

6-Iodo-4-{[4-(5-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-phenylamino]-methylene}-4H-isoquinoline-1,3-dione

(4Z)-6-(3-Methoxyphenyl)-4-({[4-(piperidin-ylmethyl)phenyl]-amino}methylene)-isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(4-Chlorophenyl)-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-[(4-Methyl-piperizin-1-yl)-4-({[4-(piperidin-1-ylmethyl)-phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Furyl)-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(4-Methoxyphenyl)-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)-isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Iodo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(Piperidin-1-ylmethyl)phenyl]amino}methylene)-6-thien-3-ylisoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4 Piperidin-1-ylmethyl]phenyl}amino)methylene)}-6-(1H-pyrrol-1-yl)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Furyl)-4-({[6-(4-methylpiperazin-1-yl)pyridin-3-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(2-Furyl)-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)-6-(3-furyl)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Furyl)-4-({[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Morpholin-4-yl-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Phenyl-4-({[4-piperidin-1-ylmethyl]phenyl}amino)-methylene)}isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Iodo-4-[({4-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]phenyl}amino)methylene]-isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(3,5-Dimethylpiperazin-1-yl)phenyl]amino}methylene)-6-iodoisoquinoline-1,3(2H,4H)-dione

(4Z)-6-(4-Phenoxyphenyl)-(4-({[4-piperidin-1-ylmethyl]phenyl}-amino)methylene)}isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(4-Fluorophenyl)-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione

6-(furan-3-yl)-4-((4-(piperidin-1-ylmethyl)phenylamino)methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Piperidin-1-yl-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-thien-3-ylisoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Furyl)-4-({[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Furyl)-4-({[5-(4-methylpiperazin-1-yl)pyrazin-2-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-phenylisoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-Piperidin-1-ylmethyl]phenyl}amino)methylene)-6-pyridin-3-ylisoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Furyl)-4-({[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-6-Chloro-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-(phenylethynyl)-isoquinoline-1,3(2H,4H)-dione

(4Z)-6-(3-Hydroxyphenyl)-4-({[4-piperidin-1-ylmethyl]phenyl}-amino)methylene)}isoquinoline-1,3(2H,4H)-dione

(4Z)-4-({[4-(3,4-Dimethylpiperazin-1-yl)phenyl]amino}methylene)-6-iodoisoquinoline-1,3(2H,4H)-dione

6-Methoxy-4-[(4-piperidin-1-ylmethyl-phenylamino)-methylene]-4H-isoquinoline-1,3-dione