Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06303 , Bile acid receptor
 Protein Info 
Gene Name NR1H4
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID Q60641
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT06303
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0550462
 Compound Info 
CHEMBL5182534
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C35H41F4N3O4
  1
1
EC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0046292
 Compound Info 
1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morpholin-4-ylpropoxy)phenyl]carbonyl}-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
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C32H38FN3O5
  1
1
EC50 = 52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0046293
 Compound Info 
propan-2-yl 1,1-dimethyl-3-[4-(3-morpholin-4-ylpropoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
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C32H39N3O5
  1
1
EC50 = 108 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426925
 Compound Info 
propan-2-yl 3-(3,4-difluorobenzoyl)-9-fluoro-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
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C25H23F3N2O3
  1
1
EC50 = 112 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0060594
 Compound Info 
WAY-362450
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C25H24F2N2O3
  1
1
EC50 = 152 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0290323
 Compound Info 
propan-2-yl 8-fluoro-1,1-dimethyl-3-[4-(2-morpholin-4-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
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C31H36FN3O5
  1
1
EC50 = 188 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0060593
 Compound Info 
propan-2-yl 1,1-dimethyl-3-[4-(2-morpholin-4-ylethoxy)benzoyl]-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
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C31H37N3O5
  1
1
EC50 = 190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0545451
 Compound Info 
6-[2-[5-cyclopropyl-3-(3,5-dichloropyridin-4-yl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-(trifluoromethyl)quinoline-2-carboxylic acid
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C30H23Cl2F3N4O3
  1
1
EC50 = 320 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS