Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06099 , Long-chain fatty acid transport protein 4
Gene Name SLC27A4
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q6P1M0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT06099
 
Compound ID Compound Name Compound Formula
CP0684205
(E)-hept-2-enyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C19H23N3O5
 1
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
CP0806976
(trans)-4-ethylcyclohexyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C20H25N3O5
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0823543
cyclohex-2-enyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H19N3O5
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0806774
(S)-cyclopentyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C17H19N3O5
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0720677
cyclopentyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C17H19N3O5
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0707883
(E)-hex-2-enyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H21N3O5
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0679829
cyclohexyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H21N3O5
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0659029
(S)-cyclopentyl 6-methyl-2-oxo-4-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H19F3N2O3
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0883782
(E)-pent-2-enyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C17H19N3O5
 1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS
CP0671206
(E)-but-2-enyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C16H17N3O5
 1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0672263
(Z)-pent-2-enyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C17H19N3O5
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0649561
cyclopentyl 4-(4-bromophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H19BrN2O3
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0651227
cyclopentyl 6-methyl-2-oxo-4-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H19F3N2O3
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0724100
cyclopentyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C17H19ClN2O3
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0780496
cyclopentyl 6-methyl-2-oxo-4-(4-(trifluoromethoxy)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H19F3N2O4
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0649600
2-(ethylthio)ethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C16H19N3O5S
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0671202
cycloheptyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C19H23N3O5
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0672325
cyclobutyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C16H17N3O5
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0662055
cyclopentyl 4-(4-cyanophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H19N3O3
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0727345
allyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C15H15N3O5
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0668372
pentyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C17H21N3O5
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0806773
(cis)-4-ethylcyclohexyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C20H25N3O5
 1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0937262
cyclopentyl 6-methyl-4-(4-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H19N3O4S
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0649484
cyclopentyl 6-methyl-2-oxo-4-p-tolyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C18H22N2O3
 1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0672288
cyclopentyl 4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C18H22N2O4
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0662056
cyclopentyl 4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H19FN2O3
 1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0721037
cyclopentyl 6-methyl-4-(4-(methylthio)phenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C18H22N2O3S
 1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0684206
5-Ethoxy-6-methyl-4-(4-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one
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C14H15N3O5
 1
1
IC50 = 9500 nM
   TI
   LI
   LO
   TS
CP0839737
cyclopentyl 4-(4-isopropoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C20H26N2O4
 1
1
IC50 = 12700 nM
   TI
   LI
   LO
   TS
CP0806974
cyclopentyl 4-(4-(dimethylamino)phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C19H25N3O3
 1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0659577
(R)-cyclopentyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H19N3O5
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0837907
cyclopentyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H20N2O4
 1
1
IC50 = 26000 nM
   TI
   LI
   LO
   TS
CP0649601
2-(ethylsulfonyl)ethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C16H19N3O7S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0649602
2-ethoxyethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C16H19N3O6
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0651222
cyclopentyl 4-(4-aminophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H21N3O3
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0668383
(R)-cyclopentyl 6-methyl-2-oxo-4-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C18H19F3N2O3
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0671200
benzyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C19H17N3O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0671207
6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
   Show/Hide
C12H11N3O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0671208
2-(ethylsulfinyl)ethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C16H19N3O6S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0766209
cyclopentyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C17H20N2O3
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0777764
5-Methoxy-6-methyl-4-(4-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one
   Show/Hide
C13H13N3O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0806770
cyclopentyl 6-methyl-4-(4-(methylsulfonyl)phenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C18H22N2O5S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0806772
phenyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
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C18H15N3O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0845751
cyclopentyl 4-(2-(4-chlorophenyl)furan-5-carbonyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C22H21ClN2O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0849075
cyclopentyl 4-(furan-2-carbonyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C16H18N2O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0878097
cyclopentyl 6-methyl-2-oxo-4-(pyridin-3-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C16H19N3O3
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0942313
cyclopentyl 6-methyl-4-(5-nitrothiophen-2-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C15H17N3O5S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0955011
cyclopentyl 4-(furan-3-carbonyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
   Show/Hide
C16H18N2O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS