Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06014 , Presenilin-1
 Protein Info 
Gene Name PSEN1
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID P49768
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT06014
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0003571
 Compound Info 
(4S,4aS,10bS)-10b-(4-chlorophenyl)sulfonyl-7,10-difluoro-4-(2-methylsulfonylethyl)-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromene
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C21H21ClF2O6S2
  2
1
IC50 = 4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0008119
 Compound Info 
(4S,4aS,10bS)-10b-(4-chlorophenyl)sulfonyl-4-(2-ethylsulfonylethyl)-7,10-difluoro-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromene
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C22H23ClF2O6S2
  1
1
IC50 = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0499914
 Compound Info 
2-[(4S,4aS,10bS)-10b-(4-chlorophenyl)sulfonyl-7,10-difluoro-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromen-4-yl]ethyl N-methylcarbamate
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C22H22ClF2NO6S
  1
1
IC50 = 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0498168
 Compound Info 
2-[(4S,4aS,10bS)-10b-(4-chlorophenyl)sulfonyl-7,10-difluoro-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromen-4-yl]ethanol
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C20H19ClF2O5S
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436251
 Compound Info 
3-[(4S,4aS,10bS)-10b-(4-chlorophenyl)sulfonyl-7,10-difluoro-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromen-4-yl]propanenitrile
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C21H18ClF2NO4S
  1
1
IC50 = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0508204
 Compound Info 
2-[(4S,4aS,10bS)-10b-(4-chlorophenyl)sulfonyl-7,10-difluoro-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromen-4-yl]ethyl N-ethylcarbamate
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C23H24ClF2NO6S
  1
1
IC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS