| Compound ID |
Compound Name |
Compound Formula |
|
CP0225161
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0390896
|
5-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
Show/Hide
|
C20H25N3S
|
1
|
| 1 |
EC50 = 3.1 nM
|
|
|
|
CP0430445
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-amine
Show/Hide
|
C22H28N4
|
1
|
| 1 |
EC50 = 3.9 nM
|
|
|
|
CP0377000
|
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0462864
|
4'-(2-(4-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)-4,5-difluorobiphenyl-2-carboxylic acid
Show/Hide
|
C25H26F2N2O2
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0402311
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
Show/Hide
|
C20H25N3S
|
1
|
| 1 |
EC50 = 6.9 nM
|
|
|
|
CP0402312
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-pyrazole
Show/Hide
|
C20H26N4
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0365995
|
4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
EC50 = 9.6 nM
|
|
|
|
CP0390895
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-ol
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0401483
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyrazine
Show/Hide
|
C21H26N4
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0507291
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1,2,3-thiadiazole
Show/Hide
|
C19H24N4S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0390897
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,4-triazole
Show/Hide
|
C19H25N5
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0401495
|
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0417715
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0401480
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-5-fluoropyridine
Show/Hide
|
C22H26FN3
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0462865
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-6-methylpyridine
Show/Hide
|
C23H29N3
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0417714
|
2-(4-(2-(4-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H25N3
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0401489
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-2H-tetrazole
Show/Hide
|
C18H24N6
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0400009
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinonitrile
Show/Hide
|
C23H26N4
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0410795
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)piperidine
Show/Hide
|
C22H33N3
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0389466
|
6-(4-tert-butylphenyl)sulfonyl-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine-2-carbonitrile
Show/Hide
|
C25H26N4O2S
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0401488
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,3-triazole
Show/Hide
|
C19H25N5
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0481364
|
7,8-dimethyl-2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C22H17F6N3O2S
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
|
CP0538376
|
2-[4-[[7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-6-yl]sulfonyl]phenyl]-2-methylpropanenitrile
Show/Hide
|
C25H23F3N4O2S
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
|
CP0414267
|
7,8-dimethyl-6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C22H17F6N3O3S
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0453510
|
7,8-dimethyl-6-(4-propan-2-ylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H24F3N3O2S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0395609
|
7,8-dimethyl-2-(trifluoromethyl)-6-[5-(trifluoromethyl)thiophen-3-yl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C20H15F6N3O2S2
|
1
|
| 1 |
EC50 = 96 nM
|
|
|
|
CP0423561
|
6-(4-tert-butylphenyl)sulfonyl-2-chloro-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H26ClN3O2S
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0395607
|
6-(4-tert-butylphenyl)sulfonyl-7-methyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H24F3N3O2S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0376662
|
10-(4-tert-butylphenyl)sulfonyl-5-(trifluoromethyl)-2,4,10,16-tetrazatetracyclo[9.8.0.03,8.012,17]nonadeca-1(11),3(8),4,6,12(17),13,15,18-octaene
Show/Hide
|
C26H23F3N4O2S
|
1
|
| 1 |
EC50 = 129 nM
|
|
|
|
CP0441855
|
2-[6-(4-tert-butylphenyl)sulfonyl-7-fluoro-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-8-yl]propan-2-ol
Show/Hide
|
C26H27F4N3O3S
|
1
|
| 1 |
EC50 = 134 nM
|
|
|
|
CP0423562
|
4-tert-butyl-2-[[7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-6-yl]sulfonyl]-1,3-thiazole
Show/Hide
|
C22H24F3N4O2S2+
|
1
|
| 1 |
EC50 = 149 nM
|
|
|
|
CP0395608
|
7,8-dimethyl-2-(trifluoromethyl)-6-[5-(trifluoromethyl)thiophen-2-yl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C20H15F6N3O2S2
|
1
|
| 1 |
EC50 = 154 nM
|
|
|
|
CP0441853
|
6-(4-tert-butylphenyl)sulfonyl-7-chloro-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C23H21ClF3N3O2S
|
1
|
| 1 |
EC50 = 155 nM
|
|
|
|
CP0423563
|
6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C23H22F3N3O2S
|
1
|
| 1 |
EC50 = 161 nM
|
|
|
|
CP0441854
|
10-(4-tert-butylphenyl)sulfonyl-13-methyl-5-(trifluoromethyl)-2,4,10,12-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
Show/Hide
|
C23H23F3N4O2S
|
1
|
| 1 |
EC50 = 171 nM
|
|
|
|
CP0523686
|
6-[4-(2-fluoropropan-2-yl)phenyl]sulfonyl-7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H23F4N3O2S
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0441859
|
6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-ol
Show/Hide
|
C23H22F3N3O3S
|
1
|
| 1 |
EC50 = 209 nM
|
|
|
|
CP0423565
|
6-(4-tert-butylphenyl)sulfonyl-2,7,8-trimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
EC50 = 232 nM
|
|
|
|
CP0395610
|
6-(4-tert-butylphenyl)sulfonyl-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H27N3O2S
|
1
|
| 1 |
EC50 = 248 nM
|
|
|
|
CP0401496
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
EC50 = 305 nM
|
|
|
|
CP0441856
|
6-(4-tert-butylphenyl)sulfonyl-2-chloro-3-fluoro-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H25ClFN3O2S
|
1
|
| 1 |
EC50 = 371 nM
|
|
|
|
CP0377610
|
6-(4-tert-butylphenyl)sulfonyl-8-methyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H24F3N3O2S
|
1
|
| 1 |
EC50 = 377 nM
|
|
|
|
CP0481277
|
7,8-dimethyl-6-(4-methylsulfonylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C22H20F3N3O4S2
|
1
|
| 1 |
EC50 = 561 nM
|
|
|
|
CP0423564
|
6-(4-tert-butylphenyl)sulfonyl-9,10-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C25H26F3N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0441858
|
6-(4-tert-butylphenyl)sulfonyl-3-chloro-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H26ClN3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
