| Compound ID |
Compound Name |
Compound Formula |
|
CP0492475
|
4-N-[(2,4-dichlorophenyl)methyl]-2-N-methyl-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C17H15Cl2N5
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0418268
|
4-N-[(4-chlorophenyl)methyl]-6-pyridin-2-yl-2-N-(2,2,2-trifluoroethyl)pyrimidine-2,4-diamine
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|
C18H15ClF3N5
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0386379
|
N-[4-[[[2-(methylamino)-6-pyridin-2-ylpyrimidin-4-yl]amino]methyl]phenyl]acetamide
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|
C19H20N6O
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0077262
|
4-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methoxy]-3-methyl-1-(7H-purin-6-yl)-5,7-dihydro-4H-pyrazolo[3,4-b]pyridin-6-one
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|
C21H18FN7O4
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0463104
|
4-N-[(4-chlorophenyl)methyl]-2-N-methyl-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C17H16ClN5
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0107678
|
4-(2-chloro-4-fluorophenyl)-3-methyl-1-(7H-purin-6-yl)-5,7-dihydro-4H-pyrazolo[3,4-b]pyridin-6-one
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|
C18H13ClFN7O
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
EC50 = 180 nM
|
|
|
|
CP0519169
|
2-N-methyl-6-pyridin-2-yl-4-N-[[4-(trifluoromethoxy)phenyl]methyl]pyrimidine-2,4-diamine
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|
C18H16F3N5O
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0459579
|
N-[4-[[[2-(methylamino)-6-pyridin-2-ylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide
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|
C18H20N6O2S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0515155
|
N-methyl-4-[[[2-(methylamino)-6-pyridin-2-ylpyrimidin-4-yl]amino]methyl]benzamide
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|
C19H20N6O
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0448155
|
4-N-(cyclohexylmethyl)-2-N-methyl-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C17H23N5
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0481891
|
N-[(4-chlorophenyl)methyl]-2-methyl-6-pyridin-2-ylpyrimidin-4-amine
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|
C17H15ClN4
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0549616
|
4-N-(cyclopropylmethyl)-6-pyridin-2-yl-2-N-[[4-(trifluoromethoxy)phenyl]methyl]pyrimidine-2,4-diamine
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|
C21H20F3N5O
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0492476
|
4-N-[1-(4-chlorophenyl)cyclobutyl]-2-N-methyl-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C20H20ClN5
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0418306
|
4-N-(cyclopropylmethyl)-2-N-methyl-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C14H17N5
|
1
|
| 1 |
EC50 = 115 nM
|
|
|
|
CP0481892
|
2-N-methyl-4-N-[(4-methylsulfonylphenyl)methyl]-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C18H19N5O2S
|
1
|
| 1 |
EC50 = 185 nM
|
|
|
|
CP0519167
|
2-N-methyl-6-pyridin-2-yl-4-N-(pyridin-4-ylmethyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H16N6
|
1
|
| 1 |
EC50 = 304 nM
|
|
|
|
CP0481890
|
4-N-(2,2-dimethylpropyl)-2-N-methyl-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C15H21N5
|
1
|
| 1 |
EC50 = 365 nM
|
|
|
|
CP0402780
|
3-methyl-4-(4-propan-2-yloxyphenyl)-1-(7H-purin-6-yl)-5,7-dihydro-4H-pyrazolo[3,4-b]pyridin-6-one
Show/Hide
|
C21H21N7O2
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0418305
|
4-N-(cyclopropylmethyl)-2-N-(2,2-dimethylpropyl)-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C18H25N5
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0398850
|
N-methyl-N-[4-[[[2-(methylamino)-6-pyridin-2-ylpyrimidin-4-yl]amino]methyl]phenyl]acetamide
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|
C20H22N6O
|
1
|
| 1 |
EC50 = 2612 nM
|
|
|
|
CP0386399
|
4-N-(cyclopropylmethyl)-2-N,2-N-dimethyl-6-pyridin-2-ylpyrimidine-2,4-diamine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
EC50 = 6716 nM
|
|
|
|
CP0519168
|
4-N-(cyclopropylmethyl)-2-N-(2-methoxyethyl)-6-pyridin-2-ylpyrimidine-2,4-diamine
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|
C16H21N5O
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0549615
|
N-(cyclopropylmethyl)-6-pyridin-2-ylpyrimidin-4-amine
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|
C13H14N4
|
1
|
| 1 |
EC50 = 10000 nM
|
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|
