| Compound ID |
Compound Name |
Compound Formula |
|
CP0428087
|
3-chloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
2
|
| 1 |
EC50 = 4.6 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0399251
|
N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H17N3
|
2
|
| 1 |
EC50 = 6.8 nM
|
|
|
| 2 |
Ki = 22 nM
|
|
|
|
CP0403660
|
US8729113, 1
Show/Hide
|
C11H14N2O2
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0452288
|
(4S)-4-(4-chloro-2-methylphenyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C10H11ClN2O
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0339222
|
US8604061, 369
Show/Hide
|
C12H13ClN2O
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0544710
|
(3S)-5-chlorospiro[2,4-dihydro-1H-naphthalene-3,4'-5H-1,3-oxazole]-2'-amine
Show/Hide
|
C12H13ClN2O
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0099315
|
(4S)-4-(3-fluoro-2-methylphenyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C10H11FN2O
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0111277
|
US8604061, 292
Show/Hide
|
C13H18N2O
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0385513
|
US8604061, 232
Show/Hide
|
C11H13ClN2O
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0176355
|
US8604061, 192
Show/Hide
|
C9H9ClN2O
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0328861
|
4-chloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0452287
|
US8604061, 4
Show/Hide
|
C9H9ClN2O
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0095112
|
US8604061, 364
Show/Hide
|
C11H13ClN2O
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0206222
|
US8604061, 80 (S)
Show/Hide
|
C11H14N2O
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0545253
|
(4S)-4-[(3-chloro-N-methylanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C11H14ClN3O
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0566841
|
(4S)-4-(3-phenylpropyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C12H16N2O
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0397937
|
(4S)-4-[(3-chloro-N-ethylanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C12H16ClN3O
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0205781
|
US8604061, 91
Show/Hide
|
C9H8Cl2N2O
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0366108
|
N-(1H-imidazol-5-ylmethyl)-3-methoxy-N-propan-2-ylaniline
Show/Hide
|
C14H19N3O
|
2
|
| 1 |
EC50 = 37 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0351659
|
N-(1H-imidazol-5-ylmethyl)-6-methoxy-N-propan-2-ylpyridin-2-amine
Show/Hide
|
C13H18N4O
|
2
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0459674
|
US8604061, 231
Show/Hide
|
C10H11BrN2O
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0403658
|
(4S)-4-[(N-ethylanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C12H17N3O
|
1
|
| 1 |
EC50 = 59 nM
|
|
|
|
CP0403659
|
(4S)-4-phenyl-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C9H10N2O
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0403661
|
(4S)-4-(2-methylphenyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C10H12N2O
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0061725
|
14C-phenylethylamine
Show/Hide
|
C8H11N
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0381900
|
(4S)-4-[(N-propan-2-ylanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C13H19N3O
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0381880
|
US8604061, 169
Show/Hide
|
C9H9ClN2O
|
1
|
| 1 |
EC50 = 143 nM
|
|
|
|
CP0210581
|
US8604061, 105
Show/Hide
|
C9H9BrN2O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0363407
|
US8604061, 60
Show/Hide
|
C10H11ClN2O
|
1
|
| 1 |
EC50 = 154 nM
|
|
|
|
CP0397938
|
US8604061, 180
Show/Hide
|
C10H11ClN2O
|
1
|
| 1 |
EC50 = 165 nM
|
|
|
|
CP0542044
|
(4R)-4-[(N-ethylanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C12H17N3O
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0212068
|
US8604061, 343
Show/Hide
|
C10H11ClN2O2
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0462140
|
3-chloro-N-(1H-imidazol-2-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
2
|
| 1 |
EC50 = 320 nM
|
|
|
| 2 |
Ki = 68 nM
|
|
|
|
CP0397943
|
(4S)-4-benzyl-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C10H12N2O
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0545042
|
US8604061, 246
Show/Hide
|
C12H15ClN2O
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0414819
|
US8604061, 350
Show/Hide
|
C11H14N2O2
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0381901
|
US8604061, 199
Show/Hide
|
C9H9FN2O
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
|
CP0459672
|
(4S)-4-[(3-chloroanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C10H12ClN3O
|
1
|
| 1 |
EC50 = 580 nM
|
|
|
|
CP0199987
|
US8604061, 82 (S,R)
Show/Hide
|
C12H16N2O
|
1
|
| 1 |
EC50 = 730 nM
|
|
|
|
CP0011288
|
2-Chloro-Phenyl biguanide
Show/Hide
|
C8H10ClN5
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0517844
|
1-(diaminomethylidene)-2-[(3,4-dichlorophenyl)methyl]guanidine
Show/Hide
|
C9H11Cl2N5
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0393245
|
N-(diaminomethylidene)-4-phenylpiperazine-1-carboximidamide
Show/Hide
|
C12H18N6
|
1
|
| 1 |
EC50 = 1380 nM
|
|
|
|
CP0338620
|
US8604061, 82 (S,S)
Show/Hide
|
C12H16N2O
|
1
|
| 1 |
EC50 = 1540 nM
|
|
|
|
CP0519601
|
1-(diaminomethylidene)-2-[(3-fluorophenyl)methyl]guanidine
Show/Hide
|
C9H12FN5
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0863688
|
1-(4'-Chlorobenzyl)biguanide dihydrochloride
Show/Hide
|
C9H14Cl3N5
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0381903
|
4-(3-phenoxyphenyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C15H14N2O2
|
1
|
| 1 |
EC50 = 1950 nM
|
|
|
|
CP0414818
|
US8604061, 293
Show/Hide
|
C13H18N2O
|
1
|
| 1 |
EC50 = 2260 nM
|
|
|
|
CP0389567
|
(4S)-4-(4-phenylphenyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C15H14N2O
|
1
|
| 1 |
EC50 = 2670 nM
|
|
|
|
CP0381899
|
(4R)-4-benzyl-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C10H12N2O
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0410151
|
2-[(2-chlorophenyl)methyl]-1-(diaminomethylidene)guanidine
Show/Hide
|
C9H12ClN5
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0930379
|
1-(3'-Bromobenzyl)biguanide dihydrochloride
Show/Hide
|
C9H14BrCl2N5
|
1
|
| 1 |
EC50 = 4900 nM
|
|
|
|
CP0394015
|
2-[(3-chlorophenyl)methyl]-1-(diaminomethylidene)guanidine
Show/Hide
|
C9H12ClN5
|
1
|
| 1 |
EC50 = 7000 nM
|
|
|
|
CP0385926
|
(4R)-4-(4-bromophenyl)-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C9H9BrN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0005986
|
4-Chloro-Phenyl biguanide
Show/Hide
|
C8H10ClN5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0339207
|
CHEBI:8455
Show/Hide
|
C11H16ClN5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0410150
|
4-Methyl-Phenyl biguanide
Show/Hide
|
C9H13N5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0481310
|
2-benzyl-1-(diaminomethylidene)guanidine
Show/Hide
|
C9H13N5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0854405
|
N-{Imino-[4-(4-methoxyphenyl)piperazin-1-yl]methyl}guanidine dihydrochloride
Show/Hide
|
C13H22Cl2N6O
|
1
|
| 1 |
EC50 = 11400 nM
|
|
|
|
CP0093317
|
3-chloro-N-ethyl-N-(1H-imidazol-5-ylmethyl)aniline
Show/Hide
|
C12H14ClN3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0539737
|
5-(2-phenylethyl)-1H-imidazole
Show/Hide
|
C11H12N2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0325965
|
3,5-dichloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H15Cl2N3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0428092
|
3,4-dichloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H15Cl2N3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0093403
|
3-chloro-N-(1H-imidazol-5-ylmethyl)-N-methylaniline
Show/Hide
|
C11H12ClN3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0263846
|
N-(1H-imidazol-5-ylmethyl)-N-methylaniline
Show/Hide
|
C11H13N3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0428094
|
1-(1H-imidazol-5-ylmethyl)-3,4-dihydro-2H-quinoline
Show/Hide
|
C13H15N3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0539736
|
3-fluoro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16FN3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0539735
|
4-fluoro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16FN3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0399253
|
2-fluoro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16FN3
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0493578
|
4-Benzyl-1H-imidazole derivative, 13
Show/Hide
|
C10H10N2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0031289
|
2-[(2,6-diethylphenyl)methyl]-1H-imidazole
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0493619
|
N-benzyl-N-(1H-imidazol-5-ylmethyl)aniline
Show/Hide
|
C17H17N3
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0481042
|
N-tert-butyl-3-chloro-N-(1H-imidazol-5-ylmethyl)aniline
Show/Hide
|
C14H18ClN3
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0459226
|
1-(1H-imidazol-5-ylmethyl)-2,3-dihydroindole
Show/Hide
|
C12H13N3
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0381253
|
2-[(2,6-dimethylphenyl)methyl]-1H-imidazole
Show/Hide
|
C12H14N2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0481043
|
2-chloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0253475
|
N-ethyl-N-(1H-imidazol-5-ylmethyl)aniline
Show/Hide
|
C12H15N3
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0459227
|
N-(1H-imidazol-5-ylmethyl)aniline
Show/Hide
|
C10H11N3
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0481044
|
N-(1H-imidazol-5-ylmethyl)-N-phenylaniline
Show/Hide
|
C16H15N3
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0428203
|
N-(1H-imidazol-5-ylmethyl)-4-methoxy-N-propan-2-ylaniline
Show/Hide
|
C14H19N3O
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0043484
|
2-(2,6-Dimethyl-benzyl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C12H16N2
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0535702
|
N-ethyl-N-(1H-imidazol-5-ylmethyl)-4-methoxypyrimidin-2-amine
Show/Hide
|
C11H15N5O
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0489573
|
N-cyclopropyl-N-(1H-imidazol-5-ylmethyl)aniline
Show/Hide
|
C13H15N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0539734
|
4-chloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylpyrimidin-2-amine
Show/Hide
|
C11H14ClN5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0381252
|
N-(1H-imidazol-5-ylmethyl)-3-methylsulfonyl-N-propan-2-ylaniline
Show/Hide
|
C14H19N3O2S
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0501052
|
4-chloro-N-(1H-imidazol-2-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0493617
|
N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylpyridin-2-amine
Show/Hide
|
C12H16N4
|
1
|
| 1 |
Ki = 195 nM
|
|
|
|
CP0493579
|
2-[(2,6-diethylphenyl)methyl]-4,5-dihydro-1H-imidazole
Show/Hide
|
C14H20N2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0381246
|
2-benzyl-1H-imidazole
Show/Hide
|
C10H10N2
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0553424
|
N-(1H-imidazol-2-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H17N3
|
1
|
| 1 |
Ki = 470 nM
|
|
|
|
CP0467341
|
2-[(2,6-dichlorophenyl)methyl]-4,5-dihydro-1H-imidazole
Show/Hide
|
C10H10Cl2N2
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0482394
|
2-[[2,6-di(propan-2-yl)phenyl]methyl]-1H-imidazole
Show/Hide
|
C16H22N2
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0539733
|
N-ethyl-N-(1H-imidazol-2-ylmethyl)aniline
Show/Hide
|
C12H15N3
|
1
|
| 1 |
Ki = 710 nM
|
|
|
|
CP0539738
|
2-[[2,6-di(propan-2-yl)phenyl]methyl]-4,5-dihydro-1H-imidazole
Show/Hide
|
C16H24N2
|
1
|
| 1 |
Ki = 825 nM
|
|
|
|
CP0499436
|
N-(1H-imidazol-2-ylmethyl)-N-methylaniline
Show/Hide
|
C11H13N3
|
1
|
| 1 |
Ki = 1270 nM
|
|
|
|
CP0499438
|
2-[(2,6-dichlorophenyl)methyl]-1H-imidazole
Show/Hide
|
C10H8Cl2N2
|
1
|
| 1 |
Ki = 1390 nM
|
|
|
|
CP0046522
|
2-(phenylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride
Show/Hide
|
C10H12N2
|
1
|
| 1 |
Ki = 1640 nM
|
|
|
|
CP0481041
|
N-(1H-imidazol-2-ylmethyl)aniline
Show/Hide
|
C10H11N3
|
1
|
| 1 |
Ki = 4250 nM
|
|
|
|
CP0522824
|
2-[[2,6-bis(trifluoromethyl)phenyl]methyl]-1H-imidazole
Show/Hide
|
C12H8F6N2
|
1
|
| 1 |
Ki = 13300 nM
|
|
|
|
CP0499439
|
2-[[2,6-bis(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole
Show/Hide
|
C12H10F6N2
|
1
|
| 1 |
Ki = 43000 nM
|
|
|
