| Compound ID |
Compound Name |
Compound Formula |
|
CP0970282
|
4-(2-Amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)but-3-yn-2-ol
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|
C17H18N4O
|
1
|
| 1 |
IC50 = 4.05 nM
|
|
|
|
CP0968902
|
1-(2-Amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-3-methylpent-1-yn-3-ol
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 9.65 nM
|
|
|
|
CP0130395
|
4-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-2-methylbut-3-yn-2-ol
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|
C20H20N4O
|
1
|
| 1 |
IC50 = 14.1 nM
|
|
|
|
CP0564497
|
4-[3-(2-aminopyrimidin-4-yl)-1H-indol-5-yl]-2-methylbut-3-yn-2-ol
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|
C17H16N4O
|
1
|
| 1 |
IC50 = 21.1 nM
|
|
|
|
CP0563006
|
2-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)ethanol
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|
C17H18N4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0964723
|
1-(2-Amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-4-methylpent-1-yn-3-ol
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|
C21H22N4O
|
1
|
| 1 |
IC50 = 45.7 nM
|
|
|
|
CP0573497
|
10-[3-(dimethylamino)prop-1-ynyl]-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine
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|
C19H19N5
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0575846
|
4-(2-amino-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-10-yl)-2-methylbut-3-yn-2-ol
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|
C19H18N4O
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0545396
|
1-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-2-methylpropan-2-ol
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0579518
|
10-(2-cyclopropylethynyl)-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine
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|
C19H16N4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0576179
|
16-(2-methoxypropan-2-yl)-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-4-amine
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 314 nM
|
|
|
|
CP0577175
|
17-[3-(dimethylamino)prop-1-ynyl]-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C21H23N5
|
1
|
| 1 |
IC50 = 683 nM
|
|
|
|
CP0495094
|
N-[2-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)propan-2-yl]methanesulfonamide
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|
C19H23N5O2S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0495098
|
2-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-2-methylpropan-1-ol
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 2160 nM
|
|
|
|
CP0573496
|
17-(4-fluorophenyl)-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C22H19FN4
|
1
|
| 1 |
IC50 = 2560 nM
|
|
|
|
CP0575250
|
10-(2-pyridin-4-ylethynyl)-6,7-dihydro-5H-pyrimido[5,4-c]carbazol-2-amine
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|
C21H15N5
|
1
|
| 1 |
IC50 = 2980 nM
|
|
|
|
CP0545395
|
17-(2-pyridin-4-ylethynyl)-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C23H19N5
|
1
|
| 1 |
IC50 = 5290 nM
|
|
|
|
CP0561400
|
17-[2-(3-methylimidazol-4-yl)ethynyl]-3,5,13-triazatetracyclo[10.7.0.02,7.014,19]nonadeca-1(12),2,4,6,14(19),15,17-heptaen-4-amine
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|
C22H20N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0575847
|
N-[2-(4-amino-3,5,12-triazatetracyclo[9.7.0.02,7.013,18]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)propan-2-yl]acetamide
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|
C20H23N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
