Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04613 , Free fatty acid receptor 1
Gene Name FFAR1
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID Q76JU9
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT04613
 
Compound ID Compound Name Compound Formula
CP0469666
3-[4-(3-ethyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C23H21N3O2
 1
1
EC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0519366
3-[3-chloro-4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H18ClN3O2
 1
1
EC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0469665
3-[4-(3-phenylmethoxy-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C28H23N3O3
 1
1
EC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0446635
3-[4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H19N3O2
 1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0543532
3-[3-fluoro-4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H18FN3O2
 1
1
EC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0394732
3-[4-(3-cyano-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H16N4O2
 1
1
EC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0430075
4-[4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]butanoic acid
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C23H21N3O2
 1
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
CP0396395
3-[4-(4-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H19N3O2
 1
1
EC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0446637
3-[4-(3-methoxy-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H19N3O3
 1
1
EC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0446638
3-[4-(4-fluoro-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C21H16FN3O2
 1
1
EC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0430079
(2S)-2-methyl-3-[4-(1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H19N3O2
 1
1
EC50 = 3800 nM
   TI
   LI
   LO
   TS
CP0475363
3-[4-(1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C21H17N3O2
 1
1
EC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0520166
3-[3-cyano-4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C23H18N4O2
 1
1
EC50 = 6100 nM
   TI
   LI
   LO
   TS
CP0408830
3-[3-methoxy-4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C23H21N3O3
 1
1
EC50 = 8200 nM
   TI
   LI
   LO
   TS
CP0539008
3-[4-(3-methyl-1-pyridin-2-ylpyrazolo[4,3-c]pyridin-6-yl)phenyl]propanoic acid
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C21H18N4O2
 1
1
EC50 = 9200 nM
   TI
   LI
   LO
   TS
CP0430076
3-[4-(4-cyano-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H16N4O2
 1
1
EC50 = 19000 nM
   TI
   LI
   LO
   TS
CP0520165
(1R,2S)-2-[4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]cyclopropane-1-carboxylic acid
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C23H19N3O2
 1
1
EC50 = 19000 nM
   TI
   LI
   LO
   TS
CP0396393
3-[4-(3-methyl-1-pyridin-2-ylpyrazolo[4,3-c]pyridin-6-yl)phenyl]butanoic acid
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C22H20N4O2
 1
1
EC50 = 61000 nM
   TI
   LI
   LO
   TS
CP0109820
(1S,2S)-2-[4-(3-methoxy-1-pyridin-2-ylindazol-6-yl)phenyl]cyclopropane-1-carboxylic acid
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C23H19N3O3
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0396394
(1S,2S)-2-[3-fluoro-4-[3-methyl-1-(5-methylpyridin-2-yl)pyrazolo[4,3-c]pyridin-6-yl]phenyl]cyclopropane-1-carboxylic acid
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C23H19FN4O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0396396
(1S,2S)-2-[4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]cyclopropane-1-carboxylic acid
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C23H19N3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0408826
(1S,2S)-2-[4-[3-methyl-1-(4-methylphenyl)pyrazolo[4,3-c]pyridin-6-yl]phenyl]cyclopropane-1-carboxylic acid
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C24H21N3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0408827
(1S,2S)-2-[4-[4-fluoro-3-methoxy-1-(4-methylphenyl)indazol-6-yl]phenyl]cyclopropane-1-carboxylic acid
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C25H21FN2O3
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0408828
(1S,2S)-2-[4-[3-methyl-1-(4-methylphenyl)indazol-6-yl]phenyl]cyclopropane-1-carboxylic acid
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C25H22N2O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0408829
2,2-dimethyl-3-[4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C24H23N3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0430074
(1S,2S)-2-[4-[4-fluoro-3-methyl-1-(4-methylphenyl)indazol-6-yl]phenyl]cyclopropane-1-carboxylic acid
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C25H21FN2O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0430078
(1R,2R)-2-[4-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]cyclopropane-1-carboxylic acid
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C23H19N3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0446633
(1S,2S)-2-[4-(4-fluoro-3-methoxy-1-pyridin-2-ylindazol-6-yl)phenyl]cyclopropane-1-carboxylic acid
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C23H18FN3O3
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0468846
(2R)-2-methyl-3-[4-(1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H19N3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0548780
3-[3-(3-methyl-1-pyridin-2-ylindazol-6-yl)phenyl]propanoic acid
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C22H19N3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS