| Compound ID |
Compound Name |
Compound Formula |
|
CP0059888
|
(2R)-2-[[2-amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H25N5OS2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0382874
|
(2R)-2-[[2-amino-5-[(2-bromophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H22BrN5OS2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0382416
|
(2R)-2-[[2-amino-5-[(1S)-1-(2-fluorophenyl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H24FN5OS2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0382414
|
5-[(1S)-1-(4-chloropyridin-2-yl)ethyl]sulfanyl-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C18H22ClN5O2S2
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0462410
|
(2R)-2-[[2-amino-5-[(1S)-1-(4-chloropyridin-2-yl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H23ClN6OS2
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0423472
|
7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-5-[(1S)-1-phenylethyl]sulfanyl-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C19H24N4O2S2
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0382421
|
7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-5-[(1R)-1-phenylethyl]sulfanyl-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C19H24N4O2S2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0488530
|
(2R)-2-[[2-amino-5-[(4-bromo-2-fluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H21BrFN5OS2
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0382418
|
methyl (2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentanoate
Show/Hide
|
C19H23N5O2S2
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0443172
|
5-[(2,3-difluorophenyl)methylsulfanyl]-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C18H20F2N4O2S2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0423471
|
(2R)-2-[[2-amino-5-[(1S)-1-(2-bromophenyl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H24BrN5OS2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0462411
|
3-[(1S)-1-[[7-[[(2R)-1-hydroxypentan-2-yl]amino]-2-oxo-3H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl]ethyl]benzonitrile
Show/Hide
|
C19H21N5O2S2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0423462
|
(2R)-2-[[2-amino-5-(2-phenylethylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H25N5OS2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0507104
|
(2R)-2-[[2-amino-5-[(1R)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H25N5OS2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0382419
|
5-[(1S)-1-(4-chloropyridin-3-yl)ethyl]sulfanyl-7-[[(2R)-1-hydroxypentan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C17H20ClN5O2S2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0382873
|
(2R)-2-[[2-amino-5-[(2-fluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H22FN5OS2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0382415
|
(2R)-2-[[2-amino-5-[(1S)-1-(3-methylsulfonylphenyl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C20H27N5O3S3
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0435855
|
5-benzylsulfanyl-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C18H22N4O2S2
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0462406
|
(2R)-2-[[2-amino-5-[(3-bromophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H22BrN5OS2
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0507102
|
3-[(1S)-1-[[2-amino-7-[[(2R)-1-hydroxypentan-2-yl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl]ethyl]benzonitrile
Show/Hide
|
C19H22N6OS2
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0435531
|
methyl (2R)-2-[[2-amino-5-[(2-chlorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentanoate
Show/Hide
|
C19H22ClN5O2S2
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0423469
|
7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-5-phenylmethoxy-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C18H22N4O3S
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0423467
|
(2R)-2-[[2-amino-5-[(4-bromophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H22BrN5OS2
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0423057
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentan-1-ol
Show/Hide
|
C18H23N5OS2
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0449542
|
(2R)-2-[[2-amino-5-[(2-chlorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H22ClN5OS2
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0473399
|
(2R)-2-[[2-amino-5-[(2-methylphenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H25N5OS2
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0423474
|
(2R)-2-[[2-amino-5-[(2,3-difluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C18H21F2N5OS2
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0462405
|
3-[[2-amino-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanylmethyl]benzonitrile
Show/Hide
|
C19H22N6OS2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0480139
|
(3R)-3-[[2-amino-5-[(2-chlorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-5-methylhexan-1-ol
Show/Hide
|
C19H24ClN5OS2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0462408
|
(2R)-2-[[2-amino-5-[(2-methoxyphenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H25N5O2S2
|
1
|
| 1 |
Ki = 99 nM
|
|
|
|
CP0455313
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]pentan-1-ol
Show/Hide
|
C17H21N5OS2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0382420
|
(2R)-2-[[2-amino-5-[(1R)-1-(2-bromophenyl)ethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C19H24BrN5OS2
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0449546
|
(2R)-2-[[2-amino-5-(3-phenylpropylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C20H27N5OS2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0507101
|
5-benzylsulfonyl-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C18H22N4O4S2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0382417
|
2-[[2-amino-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanylmethyl]benzonitrile
Show/Hide
|
C19H22N6OS2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0382876
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-3,3-dimethylbutan-1-ol
Show/Hide
|
C18H23N5OS2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0443171
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentanamide
Show/Hide
|
C18H22N6OS2
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0454405
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-2-phenylethanol
Show/Hide
|
C20H19N5OS2
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0473397
|
5-benzylsulfinyl-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C18H22N4O3S2
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0435577
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentanoic acid
Show/Hide
|
C18H21N5O2S2
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0423464
|
(2R)-2-[[2-amino-5-(pyridin-2-ylmethylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C17H22N6OS2
|
1
|
| 1 |
Ki = 360 nM
|
|
|
|
CP0465327
|
5-benzylsulfanyl-7-[[(2R)-1-hydroxybutan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C16H18N4O2S2
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0514129
|
(2S)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentan-1-ol
Show/Hide
|
C18H23N5OS2
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0507103
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-3-methylbutan-1-ol
Show/Hide
|
C17H21N5OS2
|
1
|
| 1 |
Ki = 640 nM
|
|
|
|
CP0382422
|
(2R)-2-[[2-amino-5-(pyridin-3-ylmethylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C17H22N6OS2
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0462822
|
(R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-ylamino)butan-1-ol
Show/Hide
|
C16H19N5OS2
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0423473
|
(2R)-2-[[2-amino-5-(pyridin-4-ylmethylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Show/Hide
|
C17H22N6OS2
|
1
|
| 1 |
Ki = 900 nM
|
|
|
|
CP0525678
|
(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]propan-1-ol
Show/Hide
|
C15H17N5OS2
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0435578
|
(3R)-3-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-2,5-dimethylhexan-2-ol
Show/Hide
|
C20H27N5OS2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0462404
|
4-[[2-amino-7-[[(2R)-1-hydroxy-4-methylpentan-2-yl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanylmethyl]benzonitrile
Show/Hide
|
C19H22N6OS2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0462409
|
5-benzylsulfanyl-7-[[(2R)-1-hydroxypropan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
|
C15H16N4O2S2
|
1
|
| 1 |
Ki = 29000 nM
|
|
|
