Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03645 , Nucleotide-binding oligomerization domain-containing protein 1
Gene Name NOD1
Organism Homo sapiens, Human
Protein Classification Unclassified protein
Uniprot ID Q9Y239
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT03645
 
Compound ID Compound Name Compound Formula
CP0505722
2-Amino-6-((R)-4-carboxy-4-(dodecylamino)butanamido)heptanedioic Acid
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C24H45N3O7
 1
1
EC50 = 0.023 nM
   TI
   LI
   LO
   TS
CP0505721
2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanamido)heptanedioic Acid
   Show/Hide
C24H43N3O8
 1
1
EC50 = 0.027 nM
   TI
   LI
   LO
   TS
CP0474419
2-Amino-6-((R)-4-amino-5-oxo-5-(undecyloxy)pentanamido)heptanedioic Acid
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C23H43N3O7
 1
1
EC50 = 0.066 nM
   TI
   LI
   LO
   TS
CP0437178
2-Amino-6-((R)-4-dodecanamido-5-ethoxy-5-oxopentanamido)heptanedioic Acid
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C26H47N3O8
 1
1
EC50 = 0.069 nM
   TI
   LI
   LO
   TS
CP0490822
2-Amino-6-((R)-4-carboxy-4-(dihexadecylamino)butanamido)heptanedioic Acid
   Show/Hide
C44H85N3O7
 1
1
EC50 = 0.12 nM
   TI
   LI
   LO
   TS
CP0539461
2-Amino-6-((R)-4-dodecanamido-5-oxo-5-(undecyloxy)pentanamido)heptanedioic Acid
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C35H65N3O8
 1
1
EC50 = 0.134 nM
   TI
   LI
   LO
   TS
CP0395975
(2R)-5-((6-Amino-1,7-diethoxy-1,7-dioxoheptan-2-yl)amino)-2-dodecanamido-5-oxopentanoicAcid
   Show/Hide
C28H51N3O8
 1
1
EC50 = 0.145 nM
   TI
   LI
   LO
   TS
CP0505724
diethyl 2-amino-6-[[(4R)-4-amino-5-oxo-5-undecylsulfanylpentanoyl]amino]heptanedioate
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C27H51N3O6S
 1
1
EC50 = 0.181 nM
   TI
   LI
   LO
   TS
CP0501409
2-Amino-6-((R)-4-carboxy-4-(dioctylamino)butanamido)heptanedioic Acid
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C28H53N3O7
 1
1
EC50 = 0.2 nM
   TI
   LI
   LO
   TS
CP0437177
(15R)-10,6-Dibenzyl 15-Ethyl-2,2-dimethyl-4,12,17-trioxo-3-oxa-5,11,16-triazaoctacosane-6,10,15-tricarboxylate
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C24H45N5O7
 1
1
EC50 = 0.238 nM
   TI
   LI
   LO
   TS
CP0505726
(R)-2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanamido)hexanoic Acid
   Show/Hide
C23H43N3O6
 1
1
EC50 = 0.37 nM
   TI
   LI
   LO
   TS
CP0490823
2-Amino-6-(5-oxo-5-(undecyloxy)pentanamido)heptanedioic Acid
   Show/Hide
C23H42N2O7
 1
1
EC50 = 0.39 nM
   TI
   LI
   LO
   TS
CP0395976
2-Amino-6-(4-dodecanamidobutanamido)heptanedioic Acid
   Show/Hide
C23H43N3O6
 1
1
EC50 = 0.504 nM
   TI
   LI
   LO
   TS
CP0501408
2-((R)-4-Amino-4-carboxybutanamido)-6-dodecanamidoheptanedioic Acid
   Show/Hide
C24H43N3O8
 1
1
EC50 = 0.55 nM
   TI
   LI
   LO
   TS
CP0501412
(S)-6-Amino-2-((R)-4-carboxy-4-dodecanamidobutanamido)hexanoic Acid
   Show/Hide
C23H43N3O6
 1
1
EC50 = 0.57 nM
   TI
   LI
   LO
   TS
CP0522931
2-((R)-4-Carboxy-4-dodecanamidobutanamido)-6-dodecanamidoheptanedioic Acid
   Show/Hide
C36H65N3O9
 1
1
EC50 = 0.58 nM
   TI
   LI
   LO
   TS
CP0505723
2-((R)-4-Carboxy-4-dodecanamidobutanamido)-6-guanidinoheptanedioic Acid
   Show/Hide
C25H45N5O8
 1
1
EC50 = 0.622 nM
   TI
   LI
   LO
   TS
CP0539460
2-Amino-6-((R)-4-amino-5-oxo-5-(undecylamino)pentanamido)heptanedioic Acid
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C23H44N4O6
 1
1
EC50 = 0.826 nM
   TI
   LI
   LO
   TS
CP0474420
(S)-2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanamido)hexanoic Acid
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C23H43N3O6
 1
1
EC50 = 0.96 nM
   TI
   LI
   LO
   TS
CP0933358
(2R)-5-((4-(2-Amino-4-oxo-4,5-dihydro-1H-imidazol-5-yl)-1-carboxybutyl)amino)-2-dodecanamido-5-oxopentanoic Acid
   Show/Hide
C25H43N5O7
 1
1
EC50 = 1.31 nM
   TI
   LI
   LO
   TS
CP0511809
(2R)-2-Dodecanamido-5-oxo-5-((2-oxoazepan-3-yl)amino)pentanoic Acid
   Show/Hide
C23H41N3O5
 1
1
EC50 = 1.73 nM
   TI
   LI
   LO
   TS
CP0404988
2-((R)-4-Carboxy-4-dodecanamidobutanamido)heptanedioic Acid
   Show/Hide
C24H42N2O8
 1
1
EC50 > 100 nM
   TI
   LI
   LO
   TS
CP0501410
(R)-5-((5-Aminopentyl)amino)-2-dodecanamido-5-oxopentanoic Acid
   Show/Hide
C22H43N3O4
 1
1
EC50 > 100 nM
   TI
   LI
   LO
   TS
CP0505725
(R)-6-Amino-2-((R)-4-carboxy-4-dodecanamidobutanamido)hexanoic Acid
   Show/Hide
C23H43N3O6
 1
1
EC50 > 100 nM
   TI
   LI
   LO
   TS
CP0142376
(1-tosylbenzimidazol-2-yl)amine
   Show/Hide
C14H13N3O2S
 1
1
IC50 = 771 nM
   TI
   LI
   LO
   TS
CP0552892
5-ethyl-N-[2-fluoro-5-(2-methyl-4-oxoquinazolin-3-yl)phenyl]thiophene-2-sulfonamide
   Show/Hide
C21H18FN3O3S2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0537944
2-[2-[3-[benzenesulfonyl(methyl)amino]propyl]benzimidazol-1-yl]-N-(2,3-dihydro-1H-inden-5-yl)acetamide
   Show/Hide
C28H30N4O3S
 1
1
IC50 = 1660 nM
   TI
   LI
   LO
   TS
CP0422149
2-[2-[2-[benzenesulfonyl(methyl)amino]ethyl]benzimidazol-1-yl]-N-(2,3-dihydro-1H-inden-5-yl)acetamide
   Show/Hide
C27H28N4O3S
 1
1
IC50 = 2560 nM
   TI
   LI
   LO
   TS
CP0487640
N-(2,3-dihydro-1H-inden-5-yl)-2-[2-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]ethyl]benzimidazol-1-yl]acetamide
   Show/Hide
C32H33N5O3S
 1
1
IC50 = 2680 nM
   TI
   LI
   LO
   TS
CP0422098
N-(2,3-dihydro-1H-inden-5-yl)-2-[2-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl-methylamino]ethyl]benzimidazol-1-yl]acetamide
   Show/Hide
C33H35N5O3S
 1
1
IC50 = 3080 nM
   TI
   LI
   LO
   TS
CP0534935
2-[2-[3-(benzenesulfonamido)propyl]benzimidazol-1-yl]-N-(2,3-dihydro-1H-inden-5-yl)acetamide
   Show/Hide
C27H28N4O3S
 1
1
IC50 = 9250 nM
   TI
   LI
   LO
   TS
CP0375351
4-benzyl-1-pentylbenzimidazol-2-amine
   Show/Hide
C19H23N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0375352
N-(1-pentylbenzimidazol-2-yl)acetamide
   Show/Hide
C14H19N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0375357
1-pentyl-4-phenylbenzimidazol-2-amine
   Show/Hide
C18H21N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0375359
3-pentylbenzo[f]benzimidazol-2-amine
   Show/Hide
C16H19N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0400246
1-pentylbenzo[e]benzimidazol-2-amine
   Show/Hide
C16H19N3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0410599
1-pentyl-4-phenylmethoxybenzimidazol-2-amine
   Show/Hide
C19H23N3O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0552400
3-[1-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]-N-phenylpropanamide
   Show/Hide
C27H26N4O2
 1
1
IC50 = 12400 nM
   TI
   LI
   LO
   TS
CP0422101
tert-butyl 4-[2-[1-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethylcarbamoyl]piperidine-1-carboxylate
   Show/Hide
C31H39N5O4
 1
1
IC50 = 13300 nM
   TI
   LI
   LO
   TS
CP0422152
N-[3-[1-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]propyl]benzamide
   Show/Hide
C28H28N4O2
 1
1
IC50 = 17700 nM
   TI
   LI
   LO
   TS
CP0444014
N-[2-[1-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]benzamide
   Show/Hide
C27H26N4O2
 2
1
IC50 = 27600 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0422148
N-(2,3-dihydro-1H-inden-5-yl)-2-[2-[2-(pyridin-4-ylmethylamino)ethyl]benzimidazol-1-yl]acetamide
   Show/Hide
C26H27N5O
 1
1
IC50 = 27800 nM
   TI
   LI
   LO
   TS
CP0471660
2-[2-[2-(benzenesulfonamido)ethyl]benzimidazol-1-yl]-N-(2,3-dihydro-1H-inden-5-yl)acetamide
   Show/Hide
C26H26N4O3S
 1
1
IC50 = 28200 nM
   TI
   LI
   LO
   TS
CP0552399
2-[2-[2-(benzylamino)ethyl]benzimidazol-1-yl]-N-(2,3-dihydro-1H-inden-5-yl)acetamide
   Show/Hide
C27H28N4O
 1
1
IC50 = 30700 nM
   TI
   LI
   LO
   TS
CP0422102
N-(2,3-dihydro-1H-inden-5-yl)-2-[2-[2-(pyridin-3-ylsulfonylamino)ethyl]benzimidazol-1-yl]acetamide
   Show/Hide
C25H25N5O3S
 1
1
IC50 = 32000 nM
   TI
   LI
   LO
   TS
CP0565922
N-[2-[1-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]-2-pyridin-4-ylacetamide
   Show/Hide
C27H27N5O2
 1
1
IC50 = 42300 nM
   TI
   LI
   LO
   TS