Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03475 , P2X purinoceptor 7
 Protein Info 
Gene Name P2RX7
Organism Mus musculus, Mouse
Protein Classification Ion channel
Uniprot ID Q9Z1M0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT03475
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0153595
 Compound Info 
N-[[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methyl]-2-phenylsulfanylpyridine-3-carboxamide
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C28H32N4O2S
  1
1
IC50 = 0.65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0542887
 Compound Info 
N-[(2S)-2-(4-chlorophenyl)-2-morpholin-4-ylethyl]-2-pyrimidin-2-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide
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C21H19ClF3N5O2S
  1
1
IC50 = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0447237
 Compound Info 
1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
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C19H17N5
  1
1
IC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552679
 Compound Info 
N-(cycloheptylmethyl)-1-(2-hydroxyethyl)indole-3-carboxamide
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C19H26N2O2
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064246
 Compound Info 
A-740003
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C26H30N6O3
  1
1
IC50 = 250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0407519
 Compound Info 
3-[[5-[2-chloro-3-(trifluoromethyl)phenyl]tetrazol-1-yl]methyl]pyridine
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C14H9ClF3N5
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0520236
 Compound Info 
BDBM199009
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C16H12ClF3N2O2
  1
1
IC50 = 320 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0136276
 Compound Info 
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-[4-[(2R)-2-hydroxy-3-methoxypropyl]-3,5-dioxo-1,2,4-triazin-2-yl]benzamide
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C22H29ClN4O6
  1
1
IC50 = 660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0424996
 Compound Info 
E133
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C47H49N3O7S2
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543669
 Compound Info 
AZD-9056
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C24H35ClN2O2
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0231462
 Compound Info 
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-1-methyl-5-oxopyrrolidine-2-carboxamide
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C14H14ClF3N2O2
  1
1
IC50 = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0078785
 Compound Info 
A-438079
   Show/Hide
C13H9Cl2N5
  1
1
IC50 = 2900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0502311
 Compound Info 
2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide
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C18H17ClF3N3O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS