Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03008 , Sodium channel protein type 10 subunit alpha
Gene Name SCN10A
Organism Mus musculus, Mouse
Protein Classification Ion channel
Uniprot ID Q6QIY3
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT03008
 
Compound ID Compound Name Compound Formula
CP0210100
5-(4-chlorophenyl)-N-cyano-N'-(3-methylphenyl)furan-2-carboxamide
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C19H14ClN3O
 1
1
IC50 = 30 nM
   TI
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   TS
CP0053372
N-(3,5-dimethylphenyl)-6-(4-ethoxyphenyl)pyrazine-2-carboxamide
   Show/Hide
C21H21N3O2
 1
1
IC50 = 56 nM
   TI
   LI
   LO
   TS
CP0126707
N-(3,5-dimethylphenyl)-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
   Show/Hide
C20H16F3N3O2
 1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
CP0351025
N-(3-methylphenyl)-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
   Show/Hide
C19H14F3N3O2
 1
1
IC50 = 66 nM
   TI
   LI
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   TS
CP0269891
6-(4-ethoxyphenyl)-N-[(2-methylphenyl)methyl]pyrazine-2-carboxamide
   Show/Hide
C21H21N3O2
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0105456
6-(4-chlorophenyl)-N-[(2-pyrrolidin-1-ylpyridin-3-yl)methyl]pyrazine-2-carboxamide
   Show/Hide
C21H20ClN5O
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0105457
N-[(2-methylphenyl)methyl]-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
   Show/Hide
C20H16F3N3O2
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0261810
5-[(4-trifluoromethoxy)phenyl]-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C19H14F3NO3
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0510578
5-(4-ethoxyphenyl)-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C20H19NO3
 1
1
IC50 = 430 nM
   TI
   LI
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   TS
CP0053369
6-(4-cyanophenyl)-N-(3,5-dimethylphenyl)pyrazine-2-carboxamide
   Show/Hide
C20H16N4O
 1
1
IC50 = 470 nM
   TI
   LI
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   TS
CP0201658
5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C19H14N2O2
 1
1
IC50 = 480 nM
   TI
   LI
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CP0221355
5-(4-chlorophenyl)-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C18H14ClNO2
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0243027
N-[(2-morpholin-4-ylpyridin-3-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
   Show/Hide
C22H20F3N5O3
 1
1
IC50 = 480 nM
   TI
   LI
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   TS
CP0311517
6-(4-chlorophenyl)-N-(3,5-dimethylphenyl)pyrazine-2-carboxamide
   Show/Hide
C19H16ClN3O
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0335842
6-(4-ethoxyphenyl)-N-(3-methylphenyl)pyrazine-2-carboxamide
   Show/Hide
C20H19N3O2
 1
1
IC50 = 650 nM
   TI
   LI
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   TS
CP0269893
6-(4-cyanophenyl)-N-(3-isopropoxyphenyl)pyrazine-2-carboxamide
   Show/Hide
C21H18N4O2
 1
1
IC50 = 730 nM
   TI
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CP0051021
5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
   Show/Hide
C19H16ClNO4
 1
1
IC50 = 850 nM
   TI
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   TS
CP0491980
5-(4-Chlorophenyl)furan-2-carboxylic acid-(2-piperidin-1-yl-ethyl)amide
   Show/Hide
C18H21ClN2O2
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0215373
5-(4-chlorophenyl)-N-[(5-methyl)pyridin-3-yl]furan-2-carboxamide
   Show/Hide
C17H13ClN2O2
 1
1
IC50 = 960 nM
   TI
   LI
   LO
   TS
CP0269892
6-(4-chlorophenyl)-N-(3-methylphenyl)pyrazine-2-carboxamide
   Show/Hide
C18H14ClN3O
 1
1
IC50 = 960 nM
   TI
   LI
   LO
   TS
CP0489309
5-(4-chlorophenyl)-N-(4-methyl-2,3-dihydro-1,4-benzoxazin-7-yl)furan-2-carboxamide
   Show/Hide
C20H17ClN2O3
 1
1
IC50 = 970 nM
   TI
   LI
   LO
   TS
CP0401147
[5-(4-chlorophenyl)furan-2-yl]-(4-cyclohexylpiperazin-1-yl)methanone
   Show/Hide
C21H25ClN2O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0340548
N-[(2-chloropyridin-3-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide
   Show/Hide
C18H12ClF3N4O2
 1
1
IC50 = 1030 nM
   TI
   LI
   LO
   TS
CP0335843
6-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)pyrazine-2-carboxamide
   Show/Hide
C19H16ClN3O3
 1
1
IC50 = 1070 nM
   TI
   LI
   LO
   TS
CP0535076
5-(4-chlorophenyl)-N-[(2-methylphenyl)methyl]furan-2-carboxamide
   Show/Hide
C19H16ClNO2
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0344137
6-(4-chlorophenyl)-N-[(2-methylphenyl)methyl]pyrazine-2-carboxamide
   Show/Hide
C19H16ClN3O
 1
1
IC50 = 1340 nM
   TI
   LI
   LO
   TS
CP0415542
5-(4-Chlorophenyl)furan-2-carboxylic acid (3-piperidin-1-yl-propyl)amide
   Show/Hide
C19H23ClN2O2
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0532341
5-(4-chlorophenyl)-N-[3-(cyanomethyl)phenyl]furan-2-carboxamide
   Show/Hide
C19H13ClN2O2
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0467198
5-(4-chlorophenyl)-N-[2-(2-chlorophenyl)ethyl]furan-2-carboxamide
   Show/Hide
C19H15Cl2NO2
 1
1
IC50 = 1900 nM
   TI
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   TS
CP0730899
5-(4-chlorophenyl)-N-(3-methylphenyl)furan-2-carboxamidine hydrochloride
   Show/Hide
C18H16Cl2N2O
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0522728
5-(4-Chlorophenyl)furan-2-carboxylic acid (1-methylpiperidine-dine-4-yl)amide
   Show/Hide
C17H19ClN2O2
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0418523
5-(4-Chlorophenyl)furan-2-carboxylic acid (3-dimethylamino-2,2-dimethylpropyl)amide
   Show/Hide
C18H23ClN2O2
 1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0467196
5-(4-chlorophenyl)-N-(2-methylpyridin-4-yl)furan-2-carboxamide
   Show/Hide
C17H13ClN2O2
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0532342
5-(4-chlorophenyl)-N-[3-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]furan-2-carboxamide
   Show/Hide
C20H15ClN2O3
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0088920
6-(4-chlorophenyl)-N-[(2-morpholin-4-ylpyridin-3-yl)methyl]pyrazine-2-carboxamide
   Show/Hide
C21H20ClN5O2
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0311516
6-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]pyrazine-2-carboxamide
   Show/Hide
C19H15Cl2N3O
 1
1
IC50 = 2680 nM
   TI
   LI
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   TS
CP0208887
5-(4-chlorophenyl)-N-[(1-methyl-1,2,3,4-tetrahydroquinolin)-6-yl]furan-2-carboxamide
   Show/Hide
C21H19ClN2O2
 1
1
IC50 = 2900 nM
   TI
   LI
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CP0218570
1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
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C15H15ClN2O2
 1
1
IC50 = 2900 nM
   TI
   LI
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CP0433249
5-(4-chlorophenyl)-N-(1H-indol-6-yl)furan-2-carboxamide
   Show/Hide
C19H13ClN2O2
 1
1
IC50 = 3100 nM
   TI
   LI
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   TS
CP0433248
5-(4-chlorophenyl)-N-methyl-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C19H16ClNO2
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0538412
6-(4-chlorophenyl)-N-[(3-morpholin-4-ylpyridin-4-yl)methyl]pyrazine-2-carboxamide
   Show/Hide
C21H20ClN5O2
 1
1
IC50 = 4140 nM
   TI
   LI
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   TS
CP0489310
5-(4-chlorophenyl)-N-(1-methyl-2,3-dihydroindol-6-yl)furan-2-carboxamide
   Show/Hide
C20H17ClN2O2
 1
1
IC50 = 4600 nM
   TI
   LI
   LO
   TS
CP0529688
5-(4-chlorophenyl)-N-(3-morpholin-4-ylphenyl)furan-2-carboxamide
   Show/Hide
C21H19ClN2O3
 1
1
IC50 = 4600 nM
   TI
   LI
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   TS
CP0461687
[5-(4-chlorophenyl)furan-2-yl]-[4-(dimethylamino)piperidin-1-yl]methanone
   Show/Hide
C18H21ClN2O2
 1
1
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0522360
4-(4-chlorophenyl)-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C18H14ClNO2
 1
1
IC50 = 5300 nM
   TI
   LI
   LO
   TS
CP0454089
N-(3-methylphenyl)-5-[3-(trifluoromethyl)phenyl]furan-2-carboxamide
   Show/Hide
C19H14F3NO2
 1
1
IC50 = 7500 nM
   TI
   LI
   LO
   TS
CP0354725
6-(4-cyanophenyl)-N-[(2-methylphenyl)methyl]pyrazine-2-carboxamide
   Show/Hide
C20H16N4O
 1
1
IC50 = 9400 nM
   TI
   LI
   LO
   TS
CP0522729
[5-(4-chlorophenyl)furan-2-yl]-(4-methylpiperazin-1-yl)methanone
   Show/Hide
C16H17ClN2O2
 1
1
IC50 = 9900 nM
   TI
   LI
   LO
   TS
CP0467197
5-(4-chlorophenyl)-N-quinolin-6-ylfuran-2-carboxamide
   Show/Hide
C20H13ClN2O2
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0472867
6-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)pyrazine-2-carboxamide
   Show/Hide
C17H13ClN4O
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0515530
[5-(4-chlorophenyl)furan-2-yl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
   Show/Hide
C22H18ClF3N2O2
 1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0523788
6-(4-chlorophenyl)-N-pyridin-3-ylpyrazine-2-carboxamide
   Show/Hide
C16H11ClN4O
 1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0516464
5-(4-chlorophenyl)-N-(3-methylphenyl)furan-3-carboxamide
   Show/Hide
C18H14ClNO2
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0524078
6-(4-chlorophenyl)-N-[(4-morpholin-4-ylpyridin-3-yl)methyl]pyrazine-2-carboxamide
   Show/Hide
C21H20ClN5O2
 1
1
IC50 = 29100 nM
   TI
   LI
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   TS
CP0433250
[5-(4-chlorophenyl)furan-2-yl]-morpholin-4-ylmethanone
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C15H14ClNO3
 2
1
IC50 > 30000 nM
   TI
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   TS
2
IC50 = 32000 nM
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CP0513708
5-(3-cyanophenyl)-N-(3-methylphenyl)furan-2-carboxamide
   Show/Hide
C19H14N2O2
 1
1
IC50 = 30000 nM
   TI
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   TS
CP0553011
N-(3-methylphenyl)-5-(4-methylsulfonylphenyl)furan-2-carboxamide
   Show/Hide
C19H17NO4S
 1
1
IC50 > 30000 nM
   TI
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