Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02751 , Glutamate receptor ionotropic, NMDA 2B
 Protein Info 
Gene Name GRIN2B
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q13224
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT02751
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0008860
 Compound Info 
1-((1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol
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C20H25NO3
  1
1
IC50 = 74 nM
 Bioactivity Info 
   TI
   LI
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CP0444070
 Compound Info 
4-[4-chloro-3-(difluoromethoxy)phenyl]-1-(1H-pyrazol-5-ylmethyl)pyrazole
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C14H11ClF2N4O
  1
1
IC50 = 230 nM
 Bioactivity Info 
   TI
   LI
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CP0342282
 Compound Info 
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]pyrazine-2-carboxamide
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C18H15FN4O2
  1
1
IC50 = 262 nM
 Bioactivity Info 
   TI
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CP0377015
 Compound Info 
4-[4-chloro-3-(difluoromethoxy)phenyl]-1-(1H-pyrazol-4-ylmethyl)pyrazole
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C14H11ClF2N4O
  1
1
IC50 = 350 nM
 Bioactivity Info 
   TI
   LI
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CP0446596
 Compound Info 
4-[3-(difluoromethoxy)-4-fluorophenyl]-1-(1H-pyrazol-5-ylmethyl)pyrazole
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C14H11F3N4O
  1
1
IC50 = 370 nM
 Bioactivity Info 
   TI
   LI
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CP0075084
 Compound Info 
1-cyclopropyl-N-((6-(4-fluoro-2-methoxyphenyl)pyrazin-2-yl)methyl)methanamine
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C16H18FN3O
  1
1
IC50 = 508 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0241221
 Compound Info 
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]pyridine-2-carboxamide
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C19H16FN3O2
  1
1
IC50 = 673 nM
 Bioactivity Info 
   TI
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CP0199373
 Compound Info 
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]cyclopentanamine
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C18H21FN2O
  1
1
IC50 = 770 nM
 Bioactivity Info 
   TI
   LI
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CP0446692
 Compound Info 
4-[4-chloro-3-(difluoromethyl)phenyl]-1-(1H-pyrazol-5-ylmethyl)pyrazole
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C14H11ClF2N4
  1
1
IC50 = 890 nM
 Bioactivity Info 
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CP0493632
 Compound Info 
4-[4-chloro-3-(difluoromethoxy)phenyl]-1-[(1-methylpyrazol-4-yl)methyl]pyrazole
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C15H13ClF2N4O
  1
1
IC50 = 1750 nM
 Bioactivity Info 
   TI
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CP0510167
 Compound Info 
3-[[4-[4-chloro-3-(difluoromethoxy)phenyl]pyrazol-1-yl]methyl]-1-methylpyrazole
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C15H13ClF2N4O
  1
1
IC50 = 2460 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0446693
 Compound Info 
4-[4-chloro-3-(difluoromethoxy)phenyl]-1-[(5-ethyl-1H-pyrazol-4-yl)methyl]pyrazole
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C16H15ClF2N4O
  1
1
IC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS