Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02684 , D(4) dopamine receptor
Gene Name DRD4
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P30729
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02684
 
Compound ID Compound Name Compound Formula
CP0036921
3-HYDROXYTYRAMINE HYDROCHLORIDE
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C8H11NO2
 1
1
EC50 = 2.4 nM
   TI
   LI
   LO
   TS
CP0042751
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
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C17H17NO2
 1
1
EC50 = 5.5 nM
   TI
   LI
   LO
   TS
CP0031347
2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole
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C17H19N5
 2
1
EC50 = 13.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 14.3 nM
   TI
   LI
   LO
   TS
CP0286510
6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)pyridin-3-ol
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C17H19N5O
 1
1
EC50 = 13.7 nM
   TI
   LI
   LO
   TS
CP0193372
5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1H-indole
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C18H19FN4
 1
1
EC50 = 36 nM
   TI
   LI
   LO
   TS
CP0215286
2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'bipyridine]-1'-yl)-N-(m-tolyl)acetamide
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C19H23N3O2
 1
1
EC50 = 57 nM
   TI
   LI
   LO
   TS
CP0283744
ABT-670
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C19H23N3O2
 1
1
EC50 = 93 nM
   TI
   LI
   LO
   TS
CP0378824
N-(4-fluoro-2-methylphenyl)-2-[4-(1-oxidopyridin-1-ium-2-yl)piperidin-1-yl]acetamide
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C19H22FN3O2
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0398176
N-[2-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]ethyl]-4-fluorobenzamide
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C20H21FN4O2
 1
1
Ki = 0.34 nM
   TI
   LI
   LO
   TS
CP0379634
N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-4-fluorobenzamide
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C19H20FN5O
 1
1
Ki = 0.93 nM
   TI
   LI
   LO
   TS
CP0386055
N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide
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C20H23N5O2
 1
1
Ki = 1.52 nM
   TI
   LI
   LO
   TS
CP0379633
N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-4-fluorobenzamide
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C19H21ClFN3O
 1
1
Ki = 1.76 nM
   TI
   LI
   LO
   TS
CP0496635
N-[2-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide
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C21H24N4O3
 1
1
Ki = 1.93 nM
   TI
   LI
   LO
   TS
CP0386054
4-fluoro-N-[2-[4-(4-methylphenyl)piperazin-1-yl]ethyl]benzamide
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C20H24FN3O
 1
1
Ki = 2.64 nM
   TI
   LI
   LO
   TS
CP0386056
N-[2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]ethyl]-4-fluorobenzamide
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C18H20ClFN4O
 1
1
Ki = 2.92 nM
   TI
   LI
   LO
   TS
CP0120608
N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide
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C20H24ClN3O2
 1
1
Ki = 4.97 nM
   TI
   LI
   LO
   TS
CP0112689
3-Methoxy-N-[2-(4-p-tolyl-piperazin-1-yl)-ethyl]-benzamide
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C21H27N3O2
 1
1
Ki = 9.21 nM
   TI
   LI
   LO
   TS
CP0056526
N-[2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide
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C19H23ClN4O2
 1
1
Ki = 11.29 nM
   TI
   LI
   LO
   TS
CP0379636
N-[2-[4-(4-cyanophenyl)piperazin-1-yl]ethyl]-4-fluorobenzamide
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C20H21FN4O
 1
1
Ki = 32.71 nM
   TI
   LI
   LO
   TS
CP0379635
N-[2-[4-(4-cyanophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide
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C21H24N4O2
 1
1
Ki = 63.95 nM
   TI
   LI
   LO
   TS