Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02504 , Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Gene Name PDE11A
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9HCR9
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02504
 
Compound ID Compound Name Compound Formula
CP0147040
US11419874, Example 28
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C15H10ClN5
 1
1
IC50 = 6920 nM
   TI
   LI
   LO
   TS
CP0486657
[3-([1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
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C20H23N5O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0500072
1-benzofuran-5-yl-[3-[5-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]-4-methylpiperidin-1-yl]methanone
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C21H19F2N5O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0535021
[3-[5-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methanone
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C20H21F2N5OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS