Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02205 , Cytochrome P450 1B1
Gene Name CYP1B1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q16678
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02205
 
Compound ID Compound Name Compound Formula
CP0675917
1-(pyridin-4-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one
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C17H17NO4
 2
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0853840
(E)-3-(3-Methoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C15H13NO2
 2
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0853845
(E)-3-(2-Methoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C15H13NO2
 2
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0862294
(E)-3-(3,5-Dimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C16H15NO3
 2
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0008198
2-(4-bromophenyl)-3H-quinazolin-4-one
   Show/Hide
C14H9BrN2O
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0059076
Karanjin
   Show/Hide
C18H12O4
 1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0014593
2-(4-hydroxy-3-methoxyphenyl)-3H-quinazolin-4-one
   Show/Hide
C15H12N2O3
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0393668
2-(4-prop-2-ynoxyphenyl)-3H-quinazolin-4-one
   Show/Hide
C17H12N2O2
 1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0038890
2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE
   Show/Hide
C19H12O2
 2
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0014324
2-(3'-Hydroxy-4'-methoxyphenyl)quinazolin-4(3H)-one (20)
   Show/Hide
C15H12N2O3
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0012164
2-[4-[(2,4-difluorophenyl)methoxy]phenyl]-3H-quinazolin-4-one
   Show/Hide
C21H14F2N2O2
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0014323
2-[4-(2,4-dichlorophenoxy)phenyl]-3H-quinazolin-4-one
   Show/Hide
C20H12Cl2N2O2
 1
1
IC50 = 149 nM
   TI
   LI
   LO
   TS
CP0028925
4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine
   Show/Hide
C12H9BrN4
 1
1
IC50 = 213 nM
   TI
   LI
   LO
   TS
CP0015067
4-methoxy-9-(3-methylbut-2-enoxy)-7-furo[3,2-g][1]benzopyranone
   Show/Hide
C17H16O5
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0860879
Karanjin
   Show/Hide
C18H12O4
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0853843
(E)-3-(3,4-Dimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C16H15NO3
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0155402
LANCEOLATIN B
   Show/Hide
C17H10O3
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0862295
(E)-3-(4-Ethoxy-3,5-Dimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C18H19NO4
 1
1
IC50 = 610 nM
   TI
   LI
   LO
   TS
CP0347905
(E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-one
   Show/Hide
C18H13NO
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0528337
Pongapin
   Show/Hide
C19H12O6
 1
1
IC50 = 1060 nM
   TI
   LI
   LO
   TS
CP0471583
2-(3-hydroxyphenyl)furo[2,3-h]chromen-4-one
   Show/Hide
C17H10O4
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0471582
Ovalitenone
   Show/Hide
C19H14O6
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0373903
5-demethylsinensetin
   Show/Hide
C19H18O7
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0862273
(E)-3-(3,4-diethoxy-5-methoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C19H21NO4
 1
1
IC50 = 3070 nM
   TI
   LI
   LO
   TS
CP0853844
(E)-3-(Benzo[d][1,3]dioxol-5-yl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C15H11NO3
 1
1
IC50 = 3520 nM
   TI
   LI
   LO
   TS
CP0417815
Pongamol
   Show/Hide
C18H14O4
 1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0864766
(E)-3-(3-ethoxy-4,5-dimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C18H19NO4
 1
1
IC50 = 4760 nM
   TI
   LI
   LO
   TS
CP0471581
4-[3-(4-methoxy-1-benzofuran-5-yl)-5-phenylpyrazol-1-yl]benzonitrile
   Show/Hide
C25H17N3O2
 1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
CP0891272
Pongamol
   Show/Hide
C18H14O4
 1
1
IC50 = 6040 nM
   TI
   LI
   LO
   TS
CP0058616
5-Hydroxy-2-methyl-[1,4]naphthoquinone
   Show/Hide
C11H8O3
 1
1
IC50 = 6150 nM
   TI
   LI
   LO
   TS
CP0077632
ISOPIMPINELLIN
   Show/Hide
C13H10O5
 1
1
IC50 = 6380 nM
   TI
   LI
   LO
   TS
CP0572165
Pongaglabrone
   Show/Hide
C18H10O5
 1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0860867
6-Methoxy chelerythrine
   Show/Hide
C22H21NO5
 1
1
IC50 = 7700 nM
   TI
   LI
   LO
   TS
CP0804592
(E)-1-(Pyridin-4-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
   Show/Hide
C17H17NO4
 1
1
IC50 = 8180 nM
   TI
   LI
   LO
   TS
CP0801592
3-(4-methoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one
   Show/Hide
C15H13NO2
 1
1
IC50 = 8520 nM
   TI
   LI
   LO
   TS
CP0853839
(E)-1-(pyridin-4-yl)-3-(3,4,5-triethoxyphenyl)prop-2-en-1-one
   Show/Hide
C20H23NO4
 1
1
IC50 = 9920 nM
   TI
   LI
   LO
   TS
CP0325243
5,8-Dihydroxy-[1,4]naphthoquinone
   Show/Hide
C10H6O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0046363
4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
   Show/Hide
C12H8O4
 1
1
IC50 = 15300 nM
   TI
   LI
   LO
   TS
CP0471584
4-[5-(4-methoxy-1-benzofuran-5-yl)-3-phenylpyrazol-1-yl]benzonitrile
   Show/Hide
C25H17N3O2
 1
1
IC50 = 25500 nM
   TI
   LI
   LO
   TS
CP0083020
Ammivin
   Show/Hide
C14H12O5
 1
1
IC50 = 34600 nM
   TI
   LI
   LO
   TS