| Compound ID |
Compound Name |
Compound Formula |
|
CP0422948
|
1-(4-fluorophenyl)-3-[(3S,4R)-4-(4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
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C18H18FN3O3
|
1
|
| 1 |
EC50 = 9 nM
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CP0568292
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1-(4-chlorophenyl)-3-[(3S,4S)-4-(4-methoxyphenyl)-2-oxopiperidin-3-yl]urea
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|
C19H20ClN3O3
|
1
|
| 1 |
EC50 < 10 nM
|
|
|
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CP0545858
|
1-[(3S,4R)-4-(2,5-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C18H16F3N3O3
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
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CP0552168
|
1-[(3S,4R)-4-(4-chloro-2-fluorophenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C17H14ClF2N3O2
|
1
|
| 1 |
EC50 = 29 nM
|
|
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CP0558578
|
1-(4-chloro-3-hydroxyphenyl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
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|
C18H16ClF2N3O4
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
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CP0422945
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluoro-3-hydroxyphenyl)urea
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|
C18H16F3N3O4
|
1
|
| 1 |
EC50 = 72 nM
|
|
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CP0551700
|
1-[(3S,4R)-4-(3-fluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C18H17F2N3O3
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
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CP0548203
|
1-(4-fluorophenyl)-3-[(3S,4R)-4-(4-methoxy-2-methylphenyl)-2-oxopyrrolidin-3-yl]urea
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|
C19H20FN3O3
|
1
|
| 1 |
EC50 = 76 nM
|
|
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CP0540456
|
1-[(3S,4R)-4-(2-fluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C18H17F2N3O3
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
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CP0422944
|
1-(4-bromophenyl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
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|
C18H16BrF2N3O3
|
1
|
| 1 |
EC50 = 96 nM
|
|
|
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CP0565781
|
1-(4-chlorophenyl)-3-[(3R,4R)-4-(4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
Show/Hide
|
C18H18ClN3O3
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
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CP0555981
|
1-(4-chlorophenyl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
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|
C18H16ClF2N3O3
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
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CP0561083
|
1-[(3S,4R)-4-(3-fluoro-5-methoxypyridin-2-yl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C17H16F2N4O3
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
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CP0533415
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
Show/Hide
|
C18H16F3N3O3
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
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CP0422947
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(3-methyl-1,2-thiazol-5-yl)urea
Show/Hide
|
C16H16F2N4O3S
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
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CP0422949
|
1-(4-cyanophenyl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
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|
C19H16F2N4O3
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
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CP0538091
|
1-[(3S,4R)-4-(2-chloro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C18H17ClFN3O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
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CP0513825
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(3,4-difluorophenyl)urea
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|
C18H15F4N3O3
|
1
|
| 1 |
EC50 = 820 nM
|
|
|
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CP0538094
|
1-(4-chlorophenyl)-3-[(3R,4S)-4-(4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
Show/Hide
|
C18H18ClN3O3
|
1
|
| 1 |
EC50 = 910 nM
|
|
|
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CP0553031
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C19H19F2N3O4
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
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CP0568695
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(3-hydroxy-4-methylphenyl)urea
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|
C19H19F2N3O4
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
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CP0422946
|
1-(5-chlorothiophen-2-yl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
Show/Hide
|
C16H14ClF2N3O3S
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
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CP0422943
|
1-[(3S,4R)-4-(4-ethyl-2,6-difluorophenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
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|
C19H18F3N3O2
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
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CP0552572
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(3-fluorophenyl)urea
Show/Hide
|
C18H16F3N3O3
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
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CP0540458
|
1-[(3S,4R)-4-[2,6-difluoro-4-(methylamino)phenyl]-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
Show/Hide
|
C18H17F3N4O2
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
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CP0545821
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-phenylurea
Show/Hide
|
C18H17F2N3O3
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
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CP0565860
|
1-(1-benzothiophen-2-yl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
Show/Hide
|
C20H17F2N3O3S
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
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CP0531871
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-(4-methylphenyl)urea
Show/Hide
|
C19H19F2N3O3
|
1
|
| 1 |
EC50 = 3200 nM
|
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CP0538761
|
1-(5-chloropyridin-2-yl)-3-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]urea
Show/Hide
|
C17H15ClF2N4O3
|
1
|
| 1 |
EC50 = 6900 nM
|
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CP0422942
|
1-(4-chlorophenyl)-3-[(2S,3R)-2-(4-methoxyphenyl)-4-oxoazetidin-3-yl]urea
Show/Hide
|
C17H16ClN3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0513821
|
2-[(4-chlorophenyl)carbamoylamino]-3-(4-methoxyphenyl)propanamide
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|
C17H18ClN3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0513824
|
1-(4-chlorophenyl)-3-[(2S,3S)-2-(4-methoxyphenyl)-4-oxoazetidin-3-yl]urea
Show/Hide
|
C17H16ClN3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0555979
|
1-[(3S,4R)-4-(4-cyano-2,6-difluorophenyl)-2-oxopyrrolidin-3-yl]-3-(4-fluorophenyl)urea
Show/Hide
|
C18H13F3N4O2
|
1
|
| 1 |
EC50 = 40000 nM
|
|
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CP0060183
|
N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-methoxycyclohexyl)-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C25H38N4O4S
|
1
|
| 1 |
IC50 = 3.981 nM
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CP0069784
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5-[(4-cyanophenyl)sulfonylamino]-N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-fluorophenyl)-3-methylpyrazole-4-carboxamide
Show/Hide
|
C24H26FN5O3S
|
1
|
| 1 |
IC50 = 25.12 nM
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CP0523717
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1-cyclohexyl-N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C24H36N4O3S
|
1
|
| 1 |
IC50 = 31.62 nM
|
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CP0527551
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N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-(thian-4-yl)pyrazole-4-carboxamide
Show/Hide
|
C23H34N4O3S2
|
1
|
| 1 |
IC50 = 39.81 nM
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CP0084009
|
N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-phenylpyrazole-4-carboxamide
Show/Hide
|
C24H30N4O3S
|
1
|
| 1 |
IC50 = 79.43 nM
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CP0488275
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1-cyclopentyl-N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C23H34N4O3S
|
1
|
| 1 |
IC50 = 79.43 nM
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CP0085715
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5-[(4-cyclopropylphenyl)sulfonylamino]-N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-1-(oxan-4-yl)pyrazole-4-carboxamide
Show/Hide
|
C25H36N4O4S
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1
|
| 1 |
IC50 = 158.49 nM
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CP0509112
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1-cyclobutyl-N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C22H32N4O3S
|
1
|
| 1 |
IC50 = 199.53 nM
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CP0459979
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N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-(oxan-4-yl)pyrazole-4-carboxamide
Show/Hide
|
C23H34N4O4S
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1
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| 1 |
IC50 = 316.23 nM
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CP0459980
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N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-methoxybutan-2-yl)-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C23H36N4O4S
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1
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| 1 |
IC50 = 316.23 nM
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CP0392490
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N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-pentan-3-ylpyrazole-4-carboxamide
Show/Hide
|
C23H36N4O3S
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1
|
| 1 |
IC50 = 398.11 nM
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CP0396087
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N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-propan-2-ylpyrazole-4-carboxamide
Show/Hide
|
C21H32N4O3S
|
1
|
| 1 |
IC50 = 1000 nM
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CP0525577
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N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-(oxolan-3-yl)pyrazole-4-carboxamide
Show/Hide
|
C22H32N4O4S
|
1
|
| 1 |
IC50 = 1000 nM
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CP0459981
|
1-tert-butyl-N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C22H34N4O3S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
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CP0396086
|
N-[(2S)-3,3-dimethylbutan-2-yl]-1-(1-methoxypropan-2-yl)-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C22H34N4O4S
|
1
|
| 1 |
IC50 = 2511.89 nM
|
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CP0392429
|
N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-(2,2,2-trifluoroethyl)pyrazole-4-carboxamide
Show/Hide
|
C20H27F3N4O3S
|
1
|
| 1 |
IC50 = 3162.28 nM
|
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CP0398335
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N-[(2S)-3,3-dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyrazole-4-carboxamide
Show/Hide
|
C25H36F3N5O3S
|
1
|
| 1 |
IC50 = 3162.28 nM
|
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CP0503531
|
N-[(2S)-3,3-dimethylbutan-2-yl]-1-ethyl-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C20H30N4O3S
|
1
|
| 1 |
IC50 = 6309.57 nM
|
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CP0499725
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N-[(2S)-3,3-dimethylbutan-2-yl]-1-(1,1-dioxothian-4-yl)-3-methyl-5-[(4-methylphenyl)sulfonylamino]pyrazole-4-carboxamide
Show/Hide
|
C23H34N4O5S2
|
1
|
| 1 |
IC50 = 10000 nM
|
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CP0396088
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3-methyl-5-[(4-methylphenyl)sulfonylamino]-N-pentan-3-yl-1-propan-2-ylpyrazole-4-carboxamide
Show/Hide
|
C20H30N4O3S
|
1
|
| 1 |
IC50 = 25118.86 nM
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