Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02011 , 3-hydroxy-3-methylglutaryl-coenzyme A reductase
 Protein Info 
Gene Name HMGCR
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P04035
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT02011
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0533186
 Compound Info 
4-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl]-2,6-ditert-butylpyridine
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C27H51NO6P2
  1
1
EC50 = 153 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555473
 Compound Info 
1-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl]-3,5-ditert-butylbenzene
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C28H52O6P2
  1
1
EC50 = 317 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451622
 Compound Info 
2,6-ditert-butyl-4-[2-[2-(3-but-3-ynyldiazirin-3-yl)ethoxy-propan-2-yloxyphosphoryl]-2-di(propan-2-yloxy)phosphorylethyl]pyridine
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C31H53N3O6P2
  1
1
EC50 = 417 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451620
 Compound Info 
2,6-ditert-butyl-4-[2-di(propan-2-yloxy)phosphoryl-2-[propan-2-yloxy(prop-2-ynoxy)phosphoryl]ethyl]pyridine
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C27H47NO6P2
  1
1
EC50 = 633 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451621
 Compound Info 
2,6-ditert-butyl-4-[2-[but-3-ynoxy(propan-2-yloxy)phosphoryl]-2-di(propan-2-yloxy)phosphorylethyl]pyridine
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C28H49NO6P2
  1
1
EC50 = 795 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0415891
 Compound Info 
4-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl]-2,6-ditert-butylphenol
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C28H52O7P2
  1
1
EC50 = 876 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0357968
 Compound Info 
CHEBI:77317
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C24H42O7P2
  1
1
EC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553046
 Compound Info 
1-[2,2-bis(diethoxyphosphoryl)ethenyl]-3,5-ditert-butylbenzene
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C24H42O6P2
  1
1
EC50 = 1160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0397835
 Compound Info 
4-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethenyl]-2,6-ditert-butylphenol
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C28H50O7P2
  1
1
EC50 = 1340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570652
 Compound Info 
1-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl]-3-tert-butyl-5-iodobenzene
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C24H43IO6P2
  1
1
EC50 = 1460 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533187
 Compound Info 
1-azido-3-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl]-5-tert-butylbenzene
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C24H43N3O6P2
  1
1
EC50 = 1660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553047
 Compound Info 
4-[2,2-bis(diethoxyphosphoryl)ethyl]-2,6-ditert-butylphenol
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C24H44O7P2
  1
1
EC50 = 2770 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555474
 Compound Info 
1-[2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl]-3-tert-butyl-5-ethynylbenzene
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C26H44O6P2
  1
1
EC50 = 3540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS