PRAZARELIX ACETATE

Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Aph(Ac)]-Leu-ILys-Pro-DAla-NH2

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(1S)-2-amino-1-methylsulfanyl-2-oxoethyl]pyrrolidine-2-carboxamide

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-3-(4-chlorophenyl)-1-hydroxy-2-[[(2R)-1-hydroxy-2-(1-hydroxyethylideneamino)-3-naphthalen-2-ylpropylidene]amino]propylidene]amino]-1-hydroxy-3-pyridin-3-ylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-[4-(1-hydroxyethylideneamino)phenyl]propylidene]amino]-1-hydroxy-3-[4-(1-hydroxyethylideneamino)phenyl]propylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(1R)-2-hydroxy-2-imino-1-methylsulfanylethyl]pyrrolidine-2-carboximidic acid

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-2-methylsulfanylacetyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-2-propan-2-ylsulfanylacetyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-2-propan-2-ylsulfinylacetyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-3-(4-chlorophenyl)-1-hydroxy-2-[[(2R)-1-hydroxy-2-(1-hydroxyethylideneamino)-2-naphthalen-2-ylsulfanylethylidene]amino]propylidene]amino]-1-hydroxy-3-pyridin-3-ylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-[4-(1-hydroxyethylideneamino)phenyl]propylidene]amino]-1-hydroxy-3-[4-(1-hydroxyethylideneamino)phenyl]propylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(2R)-1-hydroxy-1-iminopropan-2-yl]pyrrolidine-2-carboximidic acid

4-[[(1R)-2-[3-[(2,6-difluorophenyl)methyl]-4-methyl-2,6-dioxo-5-[4-[[5-(trifluoromethyl)furan-2-yl]methyl]piperazin-1-yl]pyrimidin-1-yl]-1-(3-fluoro-5-methylphenyl)ethyl]amino]butanoic acid

4-[[(1R)-2-[3-[(2-fluoro-6-methylphenyl)methyl]-4-methyl-2,6-dioxo-5-[4-[[5-(trifluoromethyl)furan-2-yl]methyl]piperazin-1-yl]pyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid

4-[[(1R)-2-[3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxo-5-[4-[[5-(trifluoromethyl)furan-2-yl]methyl]piperazin-1-yl]pyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid

4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[(2-fluoro-6-methylphenyl)methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid

4-[[(1R)-2-[5-[4-(2-fluoro-3-methoxyphenyl)piperazin-1-yl]-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(His), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-36-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,34,37,40,42-dodecaoxo-39-(pyridin-3-ylmethyl)-4,7,13,16,19,22,27,30,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

Gonadotropin Releasing Hormone analogue

(1R,6R,9R,15S,18R,21R,24R,34R,37S,40R)-34-acetamido-15-(3-carbamimidamidopropyl)-37-[(4-chlorophenyl)methyl]-40-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,32,35,38,41,43-dodecaoxo-4,7,13,16,19,22,27,31,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Gly), D Arg, Leu, Dbu, Pro, Dpr]GnRH

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Phe), D Cit, Leu, Dbu, Pro, Dpr]GnRH

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Sar), D Arg, Leu, Dbu, Pro, Dpr]GnRH

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Arg), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-36-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-39-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,34,37,40,42-dodecaoxo-4,7,13,16,19,22,27,30,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24R,29R,34R,37S,40R)-34-acetamido-37-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-40-(1H-indol-3-ylmethyl)-29-methyl-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,35,38,41,43-dodecaoxo-4,7,13,16,19,22,27,30,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Phe), D Arg, Leu, Dbu, Pro, Dpr]GnRH

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Cpa), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24R,34R,37S,40R)-34-acetamido-15-(3-carbamimidamidopropyl)-37-[(4-chlorophenyl)methyl]-40-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,35,38,41,43-dodecaoxo-4,7,13,16,19,22,27,30,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24S,29R,32S,35R)-29-acetamido-32-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-35-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,30,33,36,38-decaoxo-26,27-dithia-4,7,13,16,19,22,31,34,37,39-decazatricyclo[22.13.2.09,13]nonatriacontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-36-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-39-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,30,34,37,40,42-undecaoxo-4,7,13,16,19,22,29,35,38,41,43-undecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Phe), D Arg, Leu, Orn, Pro, Dpr]GnRH

Gonadotropin Releasing Hormone analogue

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(6R,9R,12S,15S)-15-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-9-[3-(diaminomethylideneamino)propyl]-12-(2-methylpropyl)-3,7,10,13-tetraoxo-2,8,11,14-tetrazabicyclo[15.2.2]henicosa-1(19),17,20-trien-6-yl]amino]-4-oxobutanoic acid

(1R,6R,9R,15S,18R,21R,24R,34R,37S,40R)-34-acetamido-37-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-40-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,29,32,35,38,41,43-dodecaoxo-4,7,13,16,19,22,28,31,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

3-[(3S,6R,9S,12R,15R,20R)-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-(4-aminobutyl)-18-(2-amino-2-oxoethyl)-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-2,5,8,11,14,17,19-heptaoxo-1,4,7,10,13,18-hexazabicyclo[18.3.0]tricosan-12-yl]propanoic acid

DiCyclo (4-10/5-8) [Ac-D Nal, D Cpa, D Trp, Asp, Glu, D Arg, Leu, Lys, Pro, D Ala]GnRH

Gonadotropin Releasing Hormone analogue

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Asp(Gly), D Arg, Leu, Dbu, Pro, Dpr]GnRH

Cyclo (4-10) [Ac-D Nal, D Fpa, D Trp, Asp, Glu, D Arg, Leu, Lys, Pro, Dpr]GnRH

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Asp(beta Ala), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-15-(3-carbamimidamidopropyl)-36-[(4-chlorophenyl)methyl]-18-(2-methylpropyl)-21,39-bis(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,34,37,40,42-dodecaoxo-4,7,13,16,19,22,27,30,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-15-(3-carbamimidamidopropyl)-36-[(4-chlorophenyl)methyl]-39-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,27,30,34,37,40,42-dodecaoxo-4,7,13,16,19,22,26,29,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24R,32R,35S,38R)-32-acetamido-35-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-38-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,27,30,33,36,39,41-dodecaoxo-4,7,13,16,19,22,26,29,34,37,40,42-dodecazatricyclo[22.16.2.09,13]dotetracontane-6-carboxamide

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Arg), D Pal, Leu, Dbu, Pro, Dpr]GnRH

Cyclo (4-10) [Ac-Delta Pro, D Fpa, D Trp, Asp, MeTyr, D Nal, Leu, Lys, Pro, Dpr]GnRH

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Asp(Phe), D Arg, Leu, Orn, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24R,34R,37S,40R)-34-acetamido-15-(3-carbamimidamidopropyl)-37-[(4-chlorophenyl)methyl]-40-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,27,31,35,38,41,43-dodecaoxo-4,7,13,16,19,22,26,30,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

Gonadotropin Releasing Hormone analogue

Cyclo (5-8) [Ac-D Nal, D Cpa, D Trp, Asp, Glu, D Nal, Leu, Lys, Pro, Dpr]GnRH

(1S,4R,7S,10S,19S,25S,28R,35S,38R,41S)-10-acetamido-7-[(4-chlorophenyl)methyl]-35-[3-(diaminomethylideneamino)propyl]-41-(2-methylpropyl)-38-(naphthalen-2-ylmethyl)-3,6,9,13,20,26,31,33,36,39,42-undecaoxo-4-(pyridin-3-ylmethyl)-2,5,8,14,21,27,30,34,37,40,43-undecazatricyclo[17.13.11.021,25]tritetracontane-28-carboxamide

(1R,6R,9R,15S,18R,21R,24R,35R,38S,41R)-35-acetamido-15-(3-carbamimidamidopropyl)-38-[(4-chlorophenyl)methyl]-41-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,29,32,36,39,42,44-dodecaoxo-4,7,13,16,19,22,28,31,37,40,43,45-dodecazatricyclo[22.19.2.09,13]pentatetracontane-6-carboxamide

DiCyclo (4-10/5-8) [Ac-D Nal, D Cpa, D Trp, Asp, Glu, D Nal, Leu, Lys, Pro, Dpr]GnRH

3-[(3S,6R,9S,12R,15R,21R)-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-aminobutyl)-19-(2-amino-2-oxoethyl)-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-2,5,8,11,14,18,20-heptaoxo-1,4,7,10,13,19-hexazabicyclo[19.3.0]tetracosan-12-yl]propanoic acid

2-[(3R,6S,9R,12S,15S,20S)-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-aminobutyl)-12-(3-amino-3-oxopropyl)-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-2,5,8,11,14,17,19-heptaoxo-1,4,7,10,13,18-hexazabicyclo[18.3.0]tricosan-18-yl]acetic acid

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(5R,8R,11S,14S)-14-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-11-(2-methylpropyl)-3,6,9,12-tetraoxo-8-(pyridin-3-ylmethyl)-2,7,10,13-tetrazabicyclo[14.2.2]icosa-1(18),16,19-trien-5-yl]amino]-4-oxobutanoic acid

DiCyclo (4-10/5-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu, D Nal, Leu, Lys, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-36-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-18-(2-methylpropyl)-3,8,14,17,20,23,28,31,34,37,40,42-dodecaoxo-21,39-bis(pyridin-3-ylmethyl)-4,7,13,16,19,22,27,30,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24R,29S,34R,37S,40R)-34-acetamido-15-(3-carbamimidamidopropyl)-37-[(4-chlorophenyl)methyl]-40-(1H-indol-3-ylmethyl)-29-methyl-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,35,38,41,43-dodecaoxo-4,7,13,16,19,22,27,30,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

Gonadotropin Releasing Hormone analogue

(1S,4R,7S,10R,19S,25S,28R,35S,38R,41S)-10-acetamido-7-[(4-chlorophenyl)methyl]-35-[3-(diaminomethylideneamino)propyl]-41-(2-methylpropyl)-38-(naphthalen-2-ylmethyl)-3,6,9,13,20,26,31,33,36,39,42-undecaoxo-4-(pyridin-3-ylmethyl)-2,5,8,14,21,27,30,34,37,40,43-undecazatricyclo[17.13.11.021,25]tritetracontane-28-carboxamide

(2S)-1-[(3S,6R,9S,12S,15S,23S)-15-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-9-[3-(diaminomethylideneamino)propyl]-12-methyl-3-(2-methylpropyl)-6-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(4R,7S,10R,13S)-4-[(2R)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidine-1-carbonyl]-10-[3-(diaminomethylideneamino)propyl]-7-(2-methylpropyl)-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradec-13-yl]amino]-4-oxobutanoic acid

(1R,6R,9R,15S,18R,21R,24R,33R,36S,39R)-33-acetamido-15-(4-aminobutyl)-36-[(4-chlorophenyl)methyl]-18-(2-methylpropyl)-3,8,14,17,20,23,28,31,34,37,40,42-dodecaoxo-16-propan-2-yl-21,39-bis(pyridin-3-ylmethyl)-4,7,13,16,19,22,27,30,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24S,34R,37S,40R)-34-acetamido-15-(3-carbamimidamidopropyl)-37-[(4-chlorophenyl)methyl]-40-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,35,38,41,43-dodecaoxo-4,7,13,16,19,22,27,30,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

(1R,6R,9R,15S,18R,21R,24S,33R,36S,39R)-33-acetamido-15-(3-carbamimidamidopropyl)-36-[(4-chlorophenyl)methyl]-39-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,28,31,34,37,40,42-dodecaoxo-4,7,13,16,19,22,27,30,35,38,41,43-dodecazatricyclo[22.17.2.09,13]tritetracontane-6-carboxamide

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(6R,9R,12S,15S)-15-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-12-(2-methylpropyl)-3,7,10,13-tetraoxo-9-(pyridin-3-ylmethyl)-2,8,11,14-tetrazabicyclo[15.2.2]henicosa-1(19),17,20-trien-6-yl]amino]-4-oxobutanoic acid

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(8R,11R,14S,17S)-17-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-11-methyl-14-(2-methylpropyl)-3,6,9,12,15-pentaoxo-2,5,10,13,16-pentazabicyclo[17.2.2]tricosa-1(21),19,22-trien-8-yl]amino]-4-oxobutanoic acid

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(Nal), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(1R,6R,9R,15S,18R,21R,24S,29R,32S,35R)-29-acetamido-32-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-35-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,27,30,33,36,38-undecaoxo-4,7,13,16,19,22,26,31,34,37,39-undecazatricyclo[22.13.2.09,13]nonatriacontane-6-carboxamide

(1R,6R,9R,15S,18R,21S,24S,29S,32S,35R)-29-acetamido-32-[(4-chlorophenyl)methyl]-15-[3-(diaminomethylideneamino)propyl]-35-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-3,8,14,17,20,23,30,33,36,38-decaoxo-26,27-dithia-4,7,13,16,19,22,31,34,37,39-decazatricyclo[22.13.2.09,13]nonatriacontane-6-carboxamide

Cyclo (5-8) [Ac-D Nal, Cpa, D Pal, Asp, D Glu, D Arg, Leu, D Orn, Pro, D Ala]GnRH

(2S)-1-[(4R,7S,10S,13S,16S,19S)-19-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-13-[3-(diaminomethylideneamino)propyl]-16-methyl-7-(2-methylpropyl)-10-(naphthalen-2-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

3-[(3R,6S,9R,12S,15S,21S,24S)-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-aminobutyl)-21-carbamoyl-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-2,5,8,11,14,17,23-heptaoxo-1,4,7,10,13,18,22-heptazabicyclo[22.3.0]heptacosan-12-yl]propanoic acid

(1R,7S,10S,15R,18S,21S,24S,34S)-34-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-18-[3-(diaminomethylideneamino)propyl]-24-(2-methylpropyl)-21-(naphthalen-2-ylmethyl)-2,8,13,16,19,22,25,32,35-nonaoxo-3,9,12,17,20,23,26,31,36-nonazatricyclo[13.11.10.03,7]hexatriacontane-10-carboxamide

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Asp(Phe), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(2S)-1-[(2S,5S,8S,11S,14S,20S)-20-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-5-[3-(diaminomethylideneamino)propyl]-2-methyl-11-(2-methylpropyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,18,21-hexaoxo-1,4,7,10,13,17-hexazacyclohenicosane-14-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(1R,4S,7S,13S,16S,21S,24R,27R,34S)-27-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-7-[3-(diaminomethylideneamino)propyl]-34-[(4-hydroxyphenyl)methyl]-24-(1H-indol-3-ylmethyl)-4-(2-methylpropyl)-2,5,8,14,19,23,26,33,36-nonaoxo-29,30-dithia-3,6,9,15,18,22,25,32,35-nonazatricyclo[19.10.5.09,13]hexatriacontane-16-carboxamide

2-[3-[(7S,13R,16S,19S,22S,25R,28R,31S,34S)-31-[(4-chlorophenyl)methyl]-25-(hydroxymethyl)-22-[(4-hydroxyphenyl)methyl]-19,28-bis(1H-indol-3-ylmethyl)-17-methyl-16-(2-methylpropyl)-2,6,12,15,18,21,24,27,30,33-decaoxo-1,5,11,14,17,20,23,26,29,32-decazatricyclo[32.3.0.07,11]heptatriacont-35-en-13-yl]propyl]guanidine

(2S)-1-[(2S,5S,8R,11S,14S,21S)-21-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-5-[3-(diaminomethylideneamino)propyl]-2-methyl-11-(2-methylpropyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,19,22-hexaoxo-1,4,7,10,13,18-hexazacyclodocosane-14-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

Gonadotropin Releasing Hormone analogue

(1R,7S,10S,15R,18S,21S,24S,34S)-34-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-21-[3-(diaminomethylideneamino)propyl]-18-[(4-hydroxyphenyl)methyl]-24-(2-methylpropyl)-2,8,13,16,19,22,25,32,35-nonaoxo-3,9,12,17,20,23,26,31,36-nonazatricyclo[13.11.10.03,7]hexatriacontane-10-carboxamide

(1R,6R,9R,15S,18R,21R,24R,34R,37S,40R)-34-acetamido-37-[(4-chlorophenyl)methyl]-15,21-bis[3-(diaminomethylideneamino)propyl]-40-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-3,8,14,17,20,23,28,31,35,38,41,43-dodecaoxo-4,7,13,16,19,22,27,30,36,39,42,44-dodecazatricyclo[22.18.2.09,13]tetratetracontane-6-carboxamide

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(6R,9R,12S,15S)-15-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-9-[3-(diaminomethylideneamino)propyl]-12-(2-methylpropyl)-3,7,10,13-tetraoxo-2,8,11,14-tetrazabicyclo[15.2.2]henicosa-1(19),17,20-trien-6-yl]amino]-4-oxobutanoic acid

(2S)-1-[(3S,6S,9S,12S,15S,18S)-18-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-15-methyl-6-(2-methylpropyl)-9-(naphthalen-2-ylmethyl)-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-3-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-N-[(2S)-1-amino-1-oxopropan-2-yl]-1-[(3S,6S,9S,12S,15S,18S,21S,32S)-9-(3-carbamimidamidopropyl)-18-[(4-chlorophenyl)methyl]-12-methyl-3-(2-methylpropyl)-6,21-bis(naphthalen-2-ylmethyl)-2,5,8,11,14,17,20,23,26-nonaoxo-15-(pyridin-3-ylmethyl)-1,4,7,10,13,16,19,22,27-nonazacyclodotriacontane-32-carbonyl]pyrrolidine-2-carboxamide

(2S)-1-[(2S,5S,8R,11S,14S,23R)-23-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-5-[3-(diaminomethylideneamino)propyl]-2-methyl-11-(2-methylpropyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,20,24-hexaoxo-1,4,7,10,13,19-hexazacyclotetracosane-14-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-1-[(2S,5S,8S,11S,14S,17S,20S,29R)-29-acetamido-2-[(4-chlorophenyl)methyl]-11-[3-(diaminomethylideneamino)propyl]-8-methyl-17-(2-methylpropyl)-14-(naphthalen-2-ylmethyl)-3,6,9,12,15,18,26,30-octaoxo-5-(pyridin-3-ylmethyl)-1,4,7,10,13,16,19,25-octazacyclotriacontane-20-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-1-[(2S,5S,8S,11S,14S,17S,20S,29S)-29-acetamido-2-[(4-chlorophenyl)methyl]-11-[3-(diaminomethylideneamino)propyl]-8-methyl-17-(2-methylpropyl)-14-(naphthalen-2-ylmethyl)-3,6,9,12,15,18,26,30-octaoxo-5-(pyridin-3-ylmethyl)-1,4,7,10,13,16,19,25-octazacyclotriacontane-20-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(2S)-1-[(3S,6S,9S,12S,15S,18S,21R)-21-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-15-methyl-6-(2-methylpropyl)-9-(naphthalen-2-ylmethyl)-5,8,11,14,17,20,23-heptaoxo-18-(pyridin-3-ylmethyl)-1,4,7,10,13,16,19-heptazacyclotricosane-3-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(1R,6R,9R,15S,18R,21S,24R,29R,32S,35R)-29-acetamido-32-[(4-chlorophenyl)methyl]-15,21-bis[3-(diaminomethylideneamino)propyl]-35-(1H-indol-3-ylmethyl)-18-(2-methylpropyl)-3,8,14,17,20,23,30,33,36,38-decaoxo-26,27-dithia-4,7,13,16,19,22,31,34,37,39-decazatricyclo[22.13.2.09,13]nonatriacontane-6-carboxamide

(2S)-1-[(2S,5S,8S,11S,14S,17S,26R)-26-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-8-[3-(diaminomethylideneamino)propyl]-5-methyl-14-(2-methylpropyl)-11-(naphthalen-2-ylmethyl)-3,6,9,12,15,23,27-heptaoxo-2-(pyridin-3-ylmethyl)-1,4,7,10,13,16,22-heptazacycloheptacosane-17-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(3S,6R,9R,18S)-18-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-6-[3-(diaminomethylideneamino)propyl]-3-(2-methylpropyl)-2,5,8,12-tetraoxo-1,4,7,13-tetrazacyclooctadec-9-yl]amino]-4-oxobutanoic acid

DiCyclo (4-10/5,5'-8) [Ac-D Nal, D Cpa, D Pal, Asp, Glu(D Phe), D Arg, Leu, Dbu, Pro, Dpr]GnRH

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(3S,6R,9R,17S)-17-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-6-[3-(diaminomethylideneamino)propyl]-3-(2-methylpropyl)-2,5,8,11-tetraoxo-1,4,7,12-tetrazacycloheptadec-9-yl]amino]-4-oxobutanoic acid

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(4S,7R,10R,13S)-4-[(2S)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-10-[3-(diaminomethylideneamino)propyl]-7-(2-methylpropyl)-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradec-13-yl]amino]-4-oxobutanoic acid

(1S,4S,7S,13S,16S,21S,24R,27S,37S)-27-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-7-[3-(diaminomethylideneamino)propyl]-37-[(4-hydroxyphenyl)methyl]-24-(1H-indol-3-ylmethyl)-4-(2-methylpropyl)-2,5,8,14,19,23,26,29,32,36,39-undecaoxo-3,6,9,15,18,22,25,30,33,35,38-undecazatricyclo[19.13.5.09,13]nonatriacontane-16-carboxamide

1-(2,6-Difluoro-benzyl)-3-[(R)-2-(2-methoxy-benzylamino)-1-methyl-ethyl]-5-(3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione