Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01897 , 5-hydroxytryptamine receptor 4
Gene Name HTR4
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID Q62758
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01897
 
Compound ID Compound Name Compound Formula
CP0148502
4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
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C23H32N2O6
 3
1
EC50 = 0.59 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.62 nM
   TI
   LI
   LO
   TS
3
EC50 = 0.65 nM
   TI
   LI
   LO
   TS
CP0376851
6-fluoro-N-[[1-[(4-hydroxyoxan-4-yl)methyl]piperidin-4-yl]methyl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide
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C23H33FN4O4
 3
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.96 nM
   TI
   LI
   LO
   TS
3
EC50 = 1.59 nM
   TI
   LI
   LO
   TS
CP0395625
6-fluoro-N-[[1-[(4-hydroxyoxan-4-yl)methyl]piperidin-4-yl]methyl]-3,3-dimethyl-2-oxoindole-1-carboxamide
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C23H32FN3O4
 3
1
EC50 = 1.15 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.52 nM
   TI
   LI
   LO
   TS
3
EC50 = 2.15 nM
   TI
   LI
   LO
   TS
CP0106868
4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide
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C18H26ClN3O3
 1
1
EC50 = 26 nM
   TI
   LI
   LO
   TS