Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01821 , Calcium-activated potassium channel subunit alpha-1
 Protein Info 
Gene Name KCNMA1
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q12791
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01821
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0393271
 Compound Info 
2-Azepan-1-yl-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C14H16N4
  1
1
EC50 = 3340 nM
 Bioactivity Info 
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CP0404746
 Compound Info 
2-Morpholin-4-yl-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C12H12N4O
  1
1
EC50 = 3860 nM
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CP0430223
 Compound Info 
2-(3-Aza-bicyclo[3.2.2]non-3-yl)-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C16H18N4
  1
1
EC50 = 4430 nM
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CP0404591
 Compound Info 
2-((S)-3-Hydroxy-piperidin-1-yl)-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C13H14N4O
  1
1
EC50 = 5070 nM
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CP0393270
 Compound Info 
2-Dimethylamino-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C10H10N4
  1
1
EC50 = 5130 nM
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CP0538288
 Compound Info 
2-Imidazol-1-yl-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C11H7N5
  1
1
EC50 = 5860 nM
 Bioactivity Info 
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CP0495748
 Compound Info 
2-[(2-Dimethylamino-ethyl)-methyl-amino]-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C13H17N5
  1
1
EC50 = 6750 nM
 Bioactivity Info 
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CP0431153
 Compound Info 
2-Diethylamino-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C12H14N4
  1
1
EC50 = 6940 nM
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CP0480727
 Compound Info 
2-Pyrrolidin-1-yl-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C12H12N4
  1
1
EC50 = 8120 nM
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CP0874517
 Compound Info 
2-Hydroxy-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C8H5N3O
  1
1
EC50 = 13400 nM
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CP0430204
 Compound Info 
2-(4-Hydroxy-piperidin-1-yl)-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile
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C13H14N4O
  1
1
EC50 = 15100 nM
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CP0462342
 Compound Info 
1-(3-Cyano-1H-pyrrolo[3,2-b]pyridin-2-yl)-piperidine-4-carboxylic acid methyl ester
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C15H16N4O2
  1
1
EC50 = 17000 nM
 Bioactivity Info 
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CP0547360
 Compound Info 
N-(5-chloro-2-methoxyphenyl)-2-[(2R)-2-methyl-4-(4-methylpiperidin-1-yl)sulfonylpiperazin-1-yl]acetamide
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C20H31ClN4O4S
  1
1
IC50 > 10000 nM
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CP0569389
 Compound Info 
N-[2-methoxy-5-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperidin-1-yl)sulfonylpiperazin-1-yl]acetamide
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C20H29F3N4O4S
  1
1
IC50 > 10000 nM
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