(3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate

ethyl 2-[2-(4-chlorophenyl)-7-methyl-5-oxoimidazo[1,2-a]pyrimidin-8-yl]acetate

[4-[[4-[(E)-[1-[(4-fluorophenyl)methyl]-3-methyl-2,5-dioxoimidazolidin-4-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid

4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid

(E)-1-(4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one

(E)-3-[4-chloro-2-[(4-methyltriazol-2-yl)methyl]phenyl]-1-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]prop-2-en-1-one

(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((5-methoxypyridin-2-yl)methyl)piperazin-1-yl)prop-2-en-1-one

[4-[[4-[(Z)-[1-[(4-fluorophenyl)methyl]-3-methyl-2,5-dioxoimidazolidin-4-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid

[4-[[4-[(E)-[1-[(4-fluorophenyl)methyl]-2,5-dioxopyrrolidin-3-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid

(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((5-methyloxazol-2-yl)methyl)piperidin-1-yl)prop-2-en-1-one

(E)-1-(4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one

[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]anilino]methyl]phenyl]boronic acid

(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]-1-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]prop-2-en-1-one

(E)-1-(4-(3-Methyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one

(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]-1-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]prop-2-en-1-one

[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenyl]carbamoyl]phenyl]boronic acid

3-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid

ATX inhibitor 10 analogue 5

(E)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]-1-[4-(trifluoromethyl)piperidin-1-yl]prop-2-en-1-one

(E)-1-(4-(3-Methyl-1H-1,2,4-triazol-1-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one

(E)-3-[4-chloro-2-(tetrazol-2-ylmethyl)phenyl]-1-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]prop-2-en-1-one

(E)-3-[4-chloro-2-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]phenyl]-1-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]prop-2-en-1-one

3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]-1-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propan-1-one

(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]-1-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one

(4-((4-((3-(4-Fluorobenzyl)-2,4-dioxothiazolidin-5-yl)methyl)phenoxy)methyl)phenyl)boronic Acid

[4-[[4-[(Z)-[1-[(4-fluorophenyl)methyl]-2,5-dioxoimidazolidin-4-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid

4-[(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]prop-2-enoyl]-1-[(3-methyl-1,2-oxazol-5-yl)methyl]piperazin-2-one

3-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid

4-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid

(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((2-methyloxazol-4-yl)methyl)piperazin-1-yl)prop-2-en-1-one

(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((1-methyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)prop-2-en-1-one

6-amino-4-(4-(dimethylamino)phenyl)-3-(4-isobutylphenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

(S)-(4-(((2-(4-Fluorobenzyl)-1,3-dioxo-1,2,3,5,10,10a-hexahydroimidazo[1,5-b]isoquinolin-7-yl)oxy)methyl)phenyl)boronic Acid

4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}-2-methoxyphenoxy)methyl]benzoic Acid

(R)-(4-(((2-(4-Fluorobenzyl)-1,3-dioxo-1,2,3,5,10,10a-hexahydroimidazo[1,5-b]isoquinolin-7-yl)oxy)methyl)phenyl)-boronic acid

(E)-1-(4-chloropiperidin-1-yl)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]prop-2-en-1-one

(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)piperidin-1-yl)prop-2-en-1-one

(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((3-methylisoxazol-5-yl)methyl)piperazin-1-yl)prop-2-en-1-one

3-(4-chlorobenzyl)-5-(3-methoxy-4-(pyridin-4-ylmethoxy)benzylidene)thiazolidine-2,4-dione

[4-[[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzoyl]amino]methyl]phenyl]boronic acid

(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]-1-[(2R)-2-methylpiperazin-1-yl]prop-2-en-1-one

3-benzyl-5-((1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methylene)thiazolidine-2,4-dione

[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzoyl]amino]phenyl]boronic acid

4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)methyl)-2-ethoxyphenoxy)methyl)benzoic acid

ATX inhibitor 10

4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)methyl)benzoic acid

1-(4-fluorophenyl)-5-(heptyliminomethyl)-6-hydroxypyrimidine-2,4-dione

N-(3-chlorophenyl)-2-[[6-(1,3-dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetamide

ATX inhibitor 8

ATX inhibitor 9

(R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-propyl ester

4-((2-methoxy-4-((3-(4-nitrobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)methyl)benzoic acid

[(2R)-3-dihydroxyphosphinothioyloxy-2-octanoyloxypropyl] octanoate

[4-[[4-[[3-[(4-fluorophenyl)methyl]-2-oxo-1,3-thiazol-5-yl]methyl]phenoxy]methyl]phenyl]boronic acid

5-(4-(benzyloxy)benzylidene)-3-(4-fluorobenzyl)thiazolidine-2,4-dione

[(2S)-3-dihydroxyphosphinothioyloxy-2-octanoyloxypropyl] octanoate

1-[(E)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]prop-2-enoyl]piperidine-4-carbonitrile

3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)methyl)benzoic acid

[4-[[4-[[3-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1,3-thiazolidin-5-yl]methyl]phenoxy]methyl]phenyl]boronic acid

(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]-1-[4-(4-fluorobenzoyl)piperazin-1-yl]prop-2-en-1-one

4-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)methyl)benzoic acid

[(2R)-2-octanoyloxy-3-phosphonooxypropyl] octanoate

3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)methyl)benzoic acid

methyl 4-[[4-[(Z)-(3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]methyl]benzoate

3-benzyl-5-(4-(benzyloxy)benzylidene)thiazolidine-2,4-dione

5-(4-(benzyloxy)-3-methoxybenzylidene)-3-(4-fluorobenzyl)thiazolidine-2,4-dione

4-((4-((3-(4-tert-butylbenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)methyl)benzoic acid

methyl 4-[[2-methoxy-4-[(Z)-[3-[(4-nitrophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methyl]benzoate

5-(4-(benzyloxy)benzylidene)-3-(4-nitrobenzyl)thiazolidine-2,4-dione

5-benzylidene-3-(4-fluorobenzyl)thiazolidine-2,4-dione

3-benzyl-5-benzylidenethiazolidine-2,4-dione

5-(4-(benzyloxy)benzylidene)-3-(4-tert-butylbenzyl)thiazolidine-2,4-dione

3-benzyl-5-(4-(benzyloxy)-3-methoxybenzylidene)thiazolidine-2,4-dione

methyl 4-[[4-[(Z)-[3-[(4-tert-butylphenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]-2-methoxyphenoxy]methyl]benzoate

methyl 4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]-2-methoxyphenoxy]methyl]benzoate

5-(4-(benzyloxy)-3-methoxybenzylidene)-3-(4-nitrobenzyl)thiazolidine-2,4-dione

2-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid

2-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden]-methyl}phenoxy)methyl]benzeneboronic Acid

[4-[(E)-2-[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenyl]ethenyl]phenyl]boronic acid