Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01780 , Sphingosine 1-phosphate receptor 5
Gene Name S1PR5
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9H228
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01780
 
Compound ID Compound Name Compound Formula
CP0144990
4-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
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C22H15F6N3O4
 1
1
EC50 = 88 nM
   TI
   LI
   LO
   TS
CP0069828
4-[5-[5-[3-cyano-5-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H15F3N4O5
 1
1
EC50 = 109 nM
   TI
   LI
   LO
   TS
CP0106364
1-[[4-[2-[3-(trifluoromethyl)phenyl]ethyl]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C20H20F3NO2
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0395086
1-[(4-nonoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C20H31NO3
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0429778
[(1R,3R)-1-amino-3-(4-octoxyphenyl)cyclopentyl]methyl dihydrogen phosphate
   Show/Hide
C20H34NO5P
 1
1
IC50 < 1 nM
   TI
   LI
   LO
   TS
CP0455679
1-[[3-chloro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H17ClF3NO3
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0467495
1-[[2-methyl-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C20H20F3NO3
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0545008
1-[[4-[(3,4-dichlorophenyl)methoxy]-2-methylphenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H19Cl2NO3
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0071903
1-[[2-fluoro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H17F4NO3
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0406156
1-[[3-fluoro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H17F4NO3
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0511184
1-[[2-chloro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H17ClF3NO3
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0071904
1-[[4-(3-methylbutoxy)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C16H23NO3
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0390300
1-[[4-(4-ethylphenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO2
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0395056
1-[[4-[(2,4-dichlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H17Cl2NO3
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0444172
1-[[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H18F3NO3
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0395057
1-[[4-[(3,4-dichlorophenyl)methoxy]-2-fluorophenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H16Cl2FNO3
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0403469
1-[(4-octoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H29NO3
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0444173
1-[[4-[(3,4-dichlorophenyl)methoxy]-3-nitrophenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H16Cl2N2O5
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0455680
1-[[4-[(3,4-dichlorophenyl)methoxy]-3-fluorophenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H16Cl2FNO3
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0032773
1-[[4-[(3,4-dichlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H17Cl2NO3
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0071902
1-[(2-chloro-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H18ClNO3
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0390374
1-[[4-(4-methylphenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H19NO2
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0397294
1-[(2-methyl-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
CP0390373
1-[(4-hexoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H25NO3
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0395085
1-[[4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H19Cl2NO4
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0457553
1-[(4-heptoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H27NO3
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0469261
1-[[4-[(4-fluorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H18FNO3
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0406228
1-[(4-pentoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C16H23NO3
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0429779
1-[[4-[(3-chlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H18ClNO3
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0457555
1-[(4-hexoxyphenyl)methyl]piperidine-4-carboxylic acid
   Show/Hide
C19H29NO3
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0467493
1-[[4-(2-phenylethyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO2
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0455676
1-[[4-(3,4-dichlorophenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H15Cl2NO2
 1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
CP0455678
(3R)-1-[(4-hexoxyphenyl)methyl]pyrrolidine-3-carboxylic acid
   Show/Hide
C18H27NO3
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0406154
1-[(4-hexoxyphenyl)methyl]-3-methylpiperidine-4-carboxylic acid
   Show/Hide
C20H31NO3
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0508743
1-[[4-[(2-methylphenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0420583
1-[(3-fluoro-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H18FNO3
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0573897
1-[(4-hexoxyphenyl)methyl]pyrrolidine-3-carboxylic acid
   Show/Hide
C18H27NO3
 1
1
IC50 = 75 nM
   TI
   LI
   LO
   TS
CP0401797
1-[(4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H19NO3
 1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
CP0545027
1-[[4-[(1R)-1-phenylethoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CP0467492
1-[[4-[(2-chlorophenyl)methoxy]-3-methoxyphenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H20ClNO4
 1
1
IC50 = 115 nM
   TI
   LI
   LO
   TS
CP0395087
(3R)-1-[(4-hexoxyphenyl)methyl]piperidine-3-carboxylic acid
   Show/Hide
C19H29NO3
 1
1
IC50 = 125 nM
   TI
   LI
   LO
   TS
CP0406229
1-[[4-(3,5-dichlorophenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H15Cl2NO2
 1
1
IC50 = 148 nM
   TI
   LI
   LO
   TS
CP0406155
1-[[4-(1-phenylethoxy)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 255 nM
   TI
   LI
   LO
   TS
CP0467491
1-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H16F3NO2
 1
1
IC50 = 409 nM
   TI
   LI
   LO
   TS
CP0469260
1-[[4-(4-chlorophenoxy)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H16ClNO3
 1
1
IC50 = 789 nM
   TI
   LI
   LO
   TS
CP0545028
(3S)-1-[(4-hexoxyphenyl)methyl]piperidine-3-carboxylic acid
   Show/Hide
C19H29NO3
 1
1
IC50 = 1210 nM
   TI
   LI
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   TS