Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01688 , Sphingosine 1-phosphate receptor 1
Gene Name S1PR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P21453
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01688
 
Compound ID Compound Name Compound Formula
CP0014534
(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
   Show/Hide
C18H38NO5P
 2
1
EC50 = 0.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 25.3 nM
   TI
   LI
   LO
   TS
CP0475087
4-[5-[5-(3-chloro-4-cyclopentylphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C25H24ClN3O4
 1
1
EC50 = 0.82 nM
   TI
   LI
   LO
   TS
CP0496179
4-[5-[5-[4-methoxy-3-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H18F3N3O6
 1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0524920
5-[3,5-bis(trifluoromethyl)phenyl]-3-(6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1,2,4-oxadiazole
   Show/Hide
C20H15F6N3O2
 1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0461758
4-[5-[5-(4-cyano-3-propan-2-yloxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C24H22N4O5
 2
1
EC50 = 1.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 6.8 nM
   TI
   LI
   LO
   TS
CP0069828
4-[5-[5-[3-cyano-5-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H15F3N4O5
 2
1
EC50 = 1.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 31 nM
   TI
   LI
   LO
   TS
CP0495456
3-[6-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-1H-benzimidazol-2-yl]propanoic acid
   Show/Hide
C20H12F6N4O3
 1
1
EC50 = 1.2 nM
   TI
   LI
   LO
   TS
CP0395118
4-oxo-4-[5-[5-[4-thiophen-2-yl-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]butanoic acid
   Show/Hide
C25H18F3N3O4S
 1
1
EC50 = 1.3 nM
   TI
   LI
   LO
   TS
CP0475088
4-[5-[5-[4-(difluoromethoxy)-3-methoxyphenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H19F2N3O6
 1
1
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0522159
(2S)-2-amino-4-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H16F6N4O4
 1
1
EC50 = 1.63 nM
   TI
   LI
   LO
   TS
CP0375346
4-[5-[5-[4-ethyl-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C23H20F3N3O4
 1
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
CP0522160
4-[5-[5-(3-bromo-4-propan-2-yloxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C23H22BrN3O5
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0499689
5-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]indazol-2-yl]pentanoic acid
   Show/Hide
C22H16F6N4O3
 1
1
EC50 = 4.2 nM
   TI
   LI
   LO
   TS
CP0401051
3-(3H-benzimidazol-5-yl)-5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazole
   Show/Hide
C17H8F6N4O
 1
1
EC50 = 4.3 nM
   TI
   LI
   LO
   TS
CP0144990
4-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H15F6N3O4
 2
1
EC50 = 4.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 39 nM
   TI
   LI
   LO
   TS
CP0393563
4-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]indazol-1-yl]butanoic acid
   Show/Hide
C21H14F6N4O3
 1
1
EC50 = 4.9 nM
   TI
   LI
   LO
   TS
CP0499690
4-[5-[5-[4-chloro-3-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C21H15ClF3N3O5
 1
1
EC50 = 5.3 nM
   TI
   LI
   LO
   TS
CP0372514
(Z,Z)-5-[3-Chloro-4-((2R)-2,3-dihydroxy-propoxy)-benzylidene]-2-propylimino-3-o-tolyl-thiazolidin-4-one
   Show/Hide
C23H25ClN2O4S
 2
1
EC50 = 5.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0427442
3-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]propanoic acid
   Show/Hide
C21H15F6N3O3
 1
1
EC50 = 6.1 nM
   TI
   LI
   LO
   TS
CP0487002
4-[5-[5-(3-cyano-4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H18N4O5
 1
1
EC50 = 6.3 nM
   TI
   LI
   LO
   TS
CP0524902
5-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-5-oxopentanoic acid
   Show/Hide
C23H17F6N3O4
 1
1
EC50 = 6.6 nM
   TI
   LI
   LO
   TS
CP0461797
5-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indazol-5-yl)-1,2,4-oxadiazole
   Show/Hide
C17H8F6N4O
 1
1
EC50 = 7.2 nM
   TI
   LI
   LO
   TS
CP0496014
3-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]indazol-1-yl]propanoic acid
   Show/Hide
C20H12F6N4O3
 1
1
EC50 = 9.8 nM
   TI
   LI
   LO
   TS
CP0395117
4-[5-[5-(3-cyano-5-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H18N4O5
 1
1
EC50 = 10.3 nM
   TI
   LI
   LO
   TS
CP0475089
4-[5-[5-[4-methoxy-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H18F3N3O5
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0475090
4-[5-[5-(3-chloro-4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C21H18ClN3O5
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0432745
4-[5-[5-(3-cyano-4-cyclopentyloxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C26H24N4O5
 1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
CP0467484
4-[5-[5-(4-methoxy-3-methylphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H21N3O5
 1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
CP0458917
5-[3,5-bis(trifluoromethyl)phenyl]-3-(1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl)-1,2,4-oxadiazole
   Show/Hide
C16H11F6N5O
 1
1
EC50 = 24 nM
   TI
   LI
   LO
   TS
CP0484567
5-[3,5-bis(trifluoromethyl)phenyl]-3-(2,3-dihydro-1H-indol-5-yl)-1,2,4-oxadiazole
   Show/Hide
C18H11F6N3O
 1
1
EC50 = 37 nM
   TI
   LI
   LO
   TS
CP0427443
4-[5-[5-(4-ethyl-3-methylsulfonylphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C23H23N3O6S
 1
1
EC50 = 38 nM
   TI
   LI
   LO
   TS
CP0523752
4-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]indol-1-yl]-4-oxobutanoic acid
   Show/Hide
C22H13F6N3O4
 1
1
EC50 = 41 nM
   TI
   LI
   LO
   TS
CP0432746
4-[5-[5-[4-[(2S)-butan-2-yl]oxy-3-chlorophenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
   Show/Hide
C24H24ClN3O5
 1
1
EC50 = 45 nM
   TI
   LI
   LO
   TS
CP0393565
2-[[2-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-1H-isoquinolin-6-yl]oxy]acetic acid
   Show/Hide
C21H15F6N3O4
 1
1
EC50 = 54 nM
   TI
   LI
   LO
   TS
CP0484568
4-oxo-4-[5-[5-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]butanoic acid
   Show/Hide
C21H16F3N3O5
 1
1
EC50 = 68 nM
   TI
   LI
   LO
   TS
CP0375345
5-[3,5-bis(trifluoromethyl)phenyl]-3-(1H-indol-5-yl)-1,2,4-oxadiazole
   Show/Hide
C18H9F6N3O
 1
1
EC50 = 75 nM
   TI
   LI
   LO
   TS
CP0524921
3-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]-3-oxopropanoic acid
   Show/Hide
C21H13F6N3O4
 1
1
EC50 = 102 nM
   TI
   LI
   LO
   TS
CP0401050
methyl 5-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]indazol-2-yl]pentanoate
   Show/Hide
C23H18F6N4O3
 1
1
EC50 = 297 nM
   TI
   LI
   LO
   TS
CP0395116
4-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-1-yl]butanoic acid
   Show/Hide
C20H17F6N5O3
 1
1
EC50 = 369 nM
   TI
   LI
   LO
   TS
CP0496178
5-[3,5-bis(trifluoromethyl)phenyl]-3-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)-1,2,4-oxadiazole
   Show/Hide
C16H11F6N5O
 1
1
EC50 = 406 nM
   TI
   LI
   LO
   TS
CP0375344
ethyl 3-[5-[5-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]indazol-1-yl]propanoate
   Show/Hide
C22H16F6N4O3
 1
1
EC50 > 100 nM
   TI
   LI
   LO
   TS
CP0429778
[(1R,3R)-1-amino-3-(4-octoxyphenyl)cyclopentyl]methyl dihydrogen phosphate
   Show/Hide
C20H34NO5P
 1
1
IC50 < 1 nM
   TI
   LI
   LO
   TS
CP0403469
1-[(4-octoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H29NO3
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0467493
1-[[4-(2-phenylethyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO2
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0093777
(2S,4R)-N-[4-(4-fluorophenoxy)phenyl]-4-[(4-fluorophenyl)methyl]-1-[2-(triazol-2-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C28H25F2N5O3
 2
1
IC50 = 4.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 21 nM
   TI
   LI
   LO
   TS
CP0395086
1-[(4-nonoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C20H31NO3
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0093776
(2S,4R)-N-[4-(4-fluorophenoxy)phenyl]-4-[(4-fluorophenyl)methyl]-1-[2-(1,2,4-triazol-1-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C28H25F2N5O3
 2
1
IC50 = 5.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0111512
(2S,4R)-N-[4-(4-fluorophenoxy)phenyl]-4-[(4-fluorophenyl)methyl]-1-[2-(triazol-1-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C28H25F2N5O3
 2
1
IC50 = 5.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0262280
(2S,4R)-4-benzyl-N-[4-(4-fluorophenoxy)phenyl]-1-[2-(1,2,4-triazol-1-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C28H26FN5O3
 2
1
IC50 = 6.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0385385
(2S)-N-[4-(4-fluorophenoxy)phenyl]-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H25FN4O4
 2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
IC50 = 284 nM
   TI
   LI
   LO
   TS
CP0558211
(2S)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-N-(4-phenoxyphenyl)-5-phenylpentanamide
   Show/Hide
C28H28N4O3
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0467494
1-[(4-decoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C21H33NO3
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0450533
(2S)-N-[4-(4-chlorophenoxy)phenyl]-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H25ClN4O4
 2
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
2
IC50 = 221 nM
   TI
   LI
   LO
   TS
CP0464386
(2S)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-N-(4-phenoxyphenyl)-3-phenylmethoxypropanamide
   Show/Hide
C27H26N4O4
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0111509
(2S,4S)-N-[4-(4-fluorophenoxy)phenyl]-4-[(4-fluorophenyl)methyl]-1-[2-(1,2,4-triazol-1-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C28H25F2N5O3
 1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
CP0457553
1-[(4-heptoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H27NO3
 1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
CP0409207
(2S)-4-benzyl-N-[4-(4-fluorophenoxy)phenyl]-1-[2-(1H-imidazol-5-yl)acetyl]piperazine-2-carboxamide
   Show/Hide
C29H28FN5O3
 1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
CP0192621
(2S,4R)-4-benzyl-N-[4-(4-fluorophenoxy)phenyl]-1-[2-(1H-imidazol-5-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C29H27FN4O3
 1
1
IC50 = 84.7 nM
   TI
   LI
   LO
   TS
CP0450534
(2S)-N-[4-(3-chlorophenoxy)phenyl]-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H25ClN4O4
 1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
CP0395085
1-[[4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H19Cl2NO4
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0409205
(2S)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxy-N-(4-phenylmethoxyphenyl)propanamide
   Show/Hide
C28H28N4O4
 1
1
IC50 = 152 nM
   TI
   LI
   LO
   TS
CP0093775
(2S,4S)-N-[4-(4-fluorophenoxy)phenyl]-1-[2-(1H-imidazol-5-yl)acetyl]-4-phenylpyrrolidine-2-carboxamide
   Show/Hide
C28H25FN4O3
 1
1
IC50 = 158 nM
   TI
   LI
   LO
   TS
CP0511852
(2S)-2-[[2-(1H-imidazol-5-yl)acetyl]-methylamino]-N-(4-phenoxyphenyl)-3-phenylmethoxypropanamide
   Show/Hide
C28H28N4O4
 1
1
IC50 = 181 nM
   TI
   LI
   LO
   TS
CP0409203
(2S)-N-(3-chloro-4-phenoxyphenyl)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H25ClN4O4
 1
1
IC50 = 211 nM
   TI
   LI
   LO
   TS
CP0444173
1-[[4-[(3,4-dichlorophenyl)methoxy]-3-nitrophenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H16Cl2N2O5
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0106364
1-[[4-[2-[3-(trifluoromethyl)phenyl]ethyl]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C20H20F3NO2
 1
1
IC50 = 221 nM
   TI
   LI
   LO
   TS
CP0409201
(2S)-2-[[2-(1-methylimidazol-4-yl)acetyl]amino]-N-(4-phenoxyphenyl)-3-phenylmethoxypropanamide
   Show/Hide
C28H28N4O4
 1
1
IC50 = 228 nM
   TI
   LI
   LO
   TS
CP0400709
N-[(1R)-1-[6-(4-fluorophenoxy)-1H-benzimidazol-2-yl]-2-phenylmethoxyethyl]-2-(1H-imidazol-5-yl)acetamide
   Show/Hide
C27H24FN5O3
 1
1
IC50 = 239 nM
   TI
   LI
   LO
   TS
CP0385381
5-oxo-N-[1-(4-phenoxyanilino)-3-phenylmethoxypropan-2-yl]-5-thiophen-2-ylpentanamide
   Show/Hide
C31H32N2O4S
 1
1
IC50 = 286 nM
   TI
   LI
   LO
   TS
CP0409200
N-[1-oxo-1-(4-phenoxyanilino)-3-phenylmethoxypropan-2-yl]cyclopropanecarboxamide
   Show/Hide
C26H26N2O4
 1
1
IC50 = 297 nM
   TI
   LI
   LO
   TS
CP0492189
(2S)-N-[4-(4-chlorophenoxy)phenyl]-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylpropanamide
   Show/Hide
C26H23ClN4O3
 1
1
IC50 = 326 nM
   TI
   LI
   LO
   TS
CP0032773
1-[[4-[(3,4-dichlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H17Cl2NO3
 1
1
IC50 = 362 nM
   TI
   LI
   LO
   TS
CP0481720
(2S,4S)-N-[4-(4-fluorophenoxy)phenyl]-4-phenyl-1-[2-(1,2,4-triazol-1-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C27H24FN5O3
 1
1
IC50 = 492 nM
   TI
   LI
   LO
   TS
CP0525004
(2S)-2-[[2-(2-fluorophenyl)acetyl]amino]-N-(4-phenoxyphenyl)-3-phenylmethoxypropanamide
   Show/Hide
C30H27FN2O4
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0409199
N-methyl-N-[2-oxo-2-[[(2S)-1-oxo-1-(4-phenoxyanilino)-3-phenylmethoxypropan-2-yl]amino]ethyl]benzamide
   Show/Hide
C32H31N3O5
 1
1
IC50 = 548 nM
   TI
   LI
   LO
   TS
CP0390300
1-[[4-(4-ethylphenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO2
 1
1
IC50 = 656 nM
   TI
   LI
   LO
   TS
CP0450536
(2S)-N-(4-cyclohexyloxyphenyl)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H32N4O4
 1
1
IC50 = 702 nM
   TI
   LI
   LO
   TS
CP0453106
N-methyl-N-[2-oxo-2-[[1-oxo-1-(4-phenoxyanilino)-3-phenylmethoxypropan-2-yl]amino]ethyl]benzamide
   Show/Hide
C32H31N3O5
 2
1
IC50 = 718 nM
   TI
   LI
   LO
   TS
2
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0536669
(2S)-N-(4-anilinophenyl)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H27N5O3
 1
1
IC50 = 743 nM
   TI
   LI
   LO
   TS
CP0429440
(2S)-N-[4-(4-chlorophenoxy)phenyl]-2-[[2-(1H-imidazol-5-yl)acetyl]amino]propanamide
   Show/Hide
C20H19ClN4O3
 1
1
IC50 = 752 nM
   TI
   LI
   LO
   TS
CP0395056
1-[[4-[(2,4-dichlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H17Cl2NO3
 1
1
IC50 = 835 nM
   TI
   LI
   LO
   TS
CP0444172
1-[[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H18F3NO3
 1
1
IC50 = 1060 nM
   TI
   LI
   LO
   TS
CP0390373
1-[(4-hexoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H25NO3
 1
1
IC50 = 1180 nM
   TI
   LI
   LO
   TS
CP0429779
1-[[4-[(3-chlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H18ClNO3
 1
1
IC50 = 1780 nM
   TI
   LI
   LO
   TS
CP0406228
1-[(4-pentoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C16H23NO3
 1
1
IC50 = 3030 nM
   TI
   LI
   LO
   TS
CP0071904
1-[[4-(3-methylbutoxy)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C16H23NO3
 1
1
IC50 = 3460 nM
   TI
   LI
   LO
   TS
CP0545027
1-[[4-[(1R)-1-phenylethoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 3870 nM
   TI
   LI
   LO
   TS
CP0397294
1-[(2-methyl-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 4170 nM
   TI
   LI
   LO
   TS
CP0071902
1-[(2-chloro-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H18ClNO3
 1
1
IC50 = 4230 nM
   TI
   LI
   LO
   TS
CP0455676
1-[[4-(3,4-dichlorophenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H15Cl2NO2
 1
1
IC50 = 4410 nM
   TI
   LI
   LO
   TS
CP0508743
1-[[4-[(2-methylphenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 = 5260 nM
   TI
   LI
   LO
   TS
CP0467492
1-[[4-[(2-chlorophenyl)methoxy]-3-methoxyphenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H20ClNO4
 1
1
IC50 = 6230 nM
   TI
   LI
   LO
   TS
CP0390374
1-[[4-(4-methylphenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H19NO2
 1
1
IC50 = 7210 nM
   TI
   LI
   LO
   TS
CP0385383
(2S)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-N-methyl-N-(4-phenoxyphenyl)-3-phenylmethoxypropanamide
   Show/Hide
C28H28N4O4
 1
1
IC50 = 8281 nM
   TI
   LI
   LO
   TS
CP0406229
1-[[4-(3,5-dichlorophenyl)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H15Cl2NO2
 1
1
IC50 = 9810 nM
   TI
   LI
   LO
   TS
CP0400706
N-methyl-N-[2-oxo-2-[[(2R)-1-oxo-1-(4-phenoxyanilino)-3-phenylmethoxypropan-2-yl]amino]ethyl]benzamide
   Show/Hide
C32H31N3O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0400708
(2S)-N-[4-(2-chlorophenoxy)phenyl]-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H25ClN4O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0409202
(2S)-2-[[2-(2,5-dichlorophenyl)acetyl]amino]-N-(4-phenoxyphenyl)-3-phenylmethoxypropanamide
   Show/Hide
C30H26Cl2N2O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0489613
(2S)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxy-N-(4-phenylphenyl)propanamide
   Show/Hide
C27H26N4O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0492188
(2S)-N-(4-benzylphenyl)-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C28H28N4O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0536668
(2S)-N-dibenzofuran-2-yl-2-[[2-(1H-imidazol-5-yl)acetyl]amino]-3-phenylmethoxypropanamide
   Show/Hide
C27H24N4O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401797
1-[(4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H19NO3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0406155
1-[[4-(1-phenylethoxy)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C19H21NO3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0467491
1-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C18H16F3NO2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0469260
1-[[4-(4-chlorophenoxy)phenyl]methyl]azetidine-3-carboxylic acid
   Show/Hide
C17H16ClNO3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0420580
[(1R,3R)-1-amino-3-(4-octoxyphenyl)cyclopentyl]methanol
   Show/Hide
C20H33NO2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0400707
N-[(2S)-1-oxo-1-(4-phenoxyanilino)-3-phenylmethoxypropan-2-yl]-1H-imidazole-5-carboxamide
   Show/Hide
C26H24N4O4
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0511853
(2R,4S)-N-[4-(4-fluorophenoxy)phenyl]-4-[(4-fluorophenyl)methyl]-1-[2-(triazol-1-yl)acetyl]pyrrolidine-2-carboxamide
   Show/Hide
C28H25F2N5O3
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS