Compound ID |
Compound Name |
Compound Formula |
CP0496360
|
N-[3-[[5-bromo-4-[3-(cyclobutanecarbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
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|
C23H30BrN7O2
|
1
|
1 |
IC50 = 72 nM
|
|
|
CP0275665
|
5-bromo-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C20H24BrN7O
|
1
|
1 |
IC50 = 214 nM
|
|
|
CP0201442
|
N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
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|
C26H36N6O2
|
1
|
1 |
IC50 = 319 nM
|
|
|
CP0237749
|
BX-912
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|
C20H23BrN8O
|
1
|
1 |
IC50 = 338 nM
|
|
|
CP0275666
|
N-[3-[[4-[3-(cyclobutanecarbonylamino)propylamino]-5-cyclopropylpyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C26H35N7O2
|
1
|
1 |
IC50 = 509 nM
|
|
|
CP0275671
|
5-cyclopropyl-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C23H29N7O
|
1
|
1 |
IC50 = 808 nM
|
|
|
CP0496361
|
N-[3-[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
Show/Hide
|
C18H23BrF3N7O
|
1
|
1 |
IC50 = 3537 nM
|
|
|
CP0496362
|
5-bromo-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrimidine-2,4-diamine
Show/Hide
|
C15H16BrF3N8
|
1
|
1 |
IC50 = 8445 nM
|
|
|
CP0169053
|
4-[[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C17H17BrF3N7O2S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0260709
|
4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrimidine-2,4-diamine
Show/Hide
|
C15H17F3N8
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0273555
|
4-[[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C25H30N6O3S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0275668
|
4-[[[5-bromo-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C22H25BrN6O3S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0275670
|
4-[[[2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C22H26N6O3S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0275672
|
N-[3-[[4-[3-(cyclobutanecarbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C23H31N7O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0275673
|
N-[3-[[5-bromo-4-[(4-sulfamoylphenyl)methylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C22H24BrN7O3S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0275674
|
5-cyclopropyl-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrimidine-2,4-diamine
Show/Hide
|
C18H21F3N8
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0344151
|
4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C20H25N7O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0496364
|
4-[[[2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C17H18F3N7O2S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0543933
|
N-[3-[[5-cyclopropyl-4-[(4-sulfamoylphenyl)methylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C25H29N7O3S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0551443
|
4-[[[5-cyclopropyl-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C20H22F3N7O2S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0551444
|
N-[3-[[4-[(4-sulfamoylphenyl)methylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C22H25N7O3S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0567307
|
N-[3-[[5-cyclopropyl-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
Show/Hide
|
C21H28F3N7O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0571203
|
N-[3-[[2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
Show/Hide
|
C18H24F3N7O
|
1
|
1 |
IC50 > 10000 nM
|
|
|