Compound ID |
Compound Name |
Compound Formula |
CP0247516
|
2,3-dichloro-N-(5-fluoro-3-methoxypyrazin-2-yl)benzenesulfonamide
Show/Hide
|
C11H8Cl2FN3O3S
|
1
|
1 |
IC50 = 3.981 nM
|
|
|
CP0405317
|
(S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]pyrimidin-2-yl)piperazin-1-yl)(piperidin-2-yl)methanone
Show/Hide
|
C24H27Cl2N7O
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0415094
|
5,7-Dihydroxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C15H18N2O4
|
1
|
1 |
IC50 = 21.2 nM
|
|
|
CP0234241
|
(R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(piperidin-2-yl)methanone
Show/Hide
|
C21H26Cl2N6O
|
1
|
1 |
IC50 = 50 nM
|
|
|
CP0502756
|
(R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(pyrrolidin-2-yl)methanone
Show/Hide
|
C20H24Cl2N6O
|
1
|
1 |
IC50 = 60 nM
|
|
|
CP0440385
|
(S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]pyrimidin-2-yl)piperazin-1-yl)(pyrrolidin-2-yl)methanone
Show/Hide
|
C23H25Cl2N7O
|
1
|
1 |
IC50 = 80 nM
|
|
|
CP0430736
|
4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N-(4-(trifluoromethoxy)phenyl)piperazine-1-carboxamide
Show/Hide
|
C22H20F3N3O6
|
1
|
1 |
IC50 = 110 nM
|
|
|
CP0387424
|
3-(4-Ethylpiperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C16H20N2O4
|
1
|
1 |
IC50 = 131 nM
|
|
|
CP0405313
|
4-N-[(2,4-dichlorophenyl)methyl]-2-N-[5-(diethylamino)pentan-2-yl]pyrido[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C23H30Cl2N6
|
1
|
1 |
IC50 = 140 nM
|
|
|
CP0510490
|
4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(piperidin-1-yl)ethoxy)-2H-chromen-2-one
Show/Hide
|
C22H31N3O3
|
1
|
1 |
IC50 = 196 nM
|
|
|
CP0465234
|
1-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-amine
Show/Hide
|
C22H29Cl2N5
|
1
|
1 |
IC50 = 280 nM
|
|
|
CP0894039
|
N4-(2,4-dichlorobenzyl)-N2-(4-(diethylamino)pentyl)pyrimidine-2,4-diamine
Show/Hide
|
C20H32Cl2N6
|
1
|
1 |
IC50 = 280 nM
|
|
|
CP0442868
|
(4-(2-(2,4-dichlorobenzylamino)pyrimidin-4-yl)piperazin-1-yl)(1-methylpiperidin-3-yl)methanone
Show/Hide
|
C22H28Cl2N6O
|
1
|
1 |
IC50 = 300 nM
|
|
|
CP0501384
|
5-Hydroxy-7-methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C16H20N2O4
|
1
|
1 |
IC50 = 389 nM
|
|
|
CP0387428
|
8-Methyl-7-(4-methylpiperazin-1-yl)-6H-[1,3]dioxolo[4,5-g]-chromen-6-one
Show/Hide
|
C16H18N2O4
|
1
|
1 |
IC50 = 420 nM
|
|
|
CP0497041
|
5,7-Dimethoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C17H22N2O4
|
1
|
1 |
IC50 = 478 nM
|
|
|
CP0435635
|
4-N-[(2,4-dichlorophenyl)methyl]-2-N-[5-(diethylamino)pentan-2-yl]quinazoline-2,4-diamine
Show/Hide
|
C24H31Cl2N5
|
1
|
1 |
IC50 = 500 nM
|
|
|
CP0423569
|
4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(thiophen-2-yl)ethoxy)-2H-chromen-2-one
Show/Hide
|
C21H24N2O3S
|
1
|
1 |
IC50 = 527 nM
|
|
|
CP0517554
|
4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N-heptylpiperazine-1-carboxamide
Show/Hide
|
C22H31N3O5
|
1
|
1 |
IC50 = 539 nM
|
|
|
CP0494418
|
4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-morpholinoethoxy)-2H-chromen-2-one
Show/Hide
|
C21H29N3O4
|
1
|
1 |
IC50 = 671 nM
|
|
|
CP0523168
|
(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(1-methylpiperidin-3-yl)methanone
Show/Hide
|
C22H28Cl2N6O
|
1
|
1 |
IC50 = 700 nM
|
|
|
CP0430739
|
7-Hydroxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C15H18N2O3
|
1
|
1 |
IC50 = 775 nM
|
|
|
CP0464678
|
(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(piperidin-3-yl)methanone
Show/Hide
|
C21H26Cl2N6O
|
1
|
1 |
IC50 = 800 nM
|
|
|
CP0458918
|
9-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2-yl)-9H-purin-2-amine
Show/Hide
|
C21H28Cl2N6
|
1
|
1 |
IC50 = 820 nM
|
|
|
CP0405316
|
7-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2-yl)-7H-purin-2-amine
Show/Hide
|
C21H28Cl2N6
|
1
|
1 |
IC50 = 830 nM
|
|
|
CP0453765
|
(S)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(piperidin-2-yl)methanone
Show/Hide
|
C21H26Cl2N6O
|
1
|
1 |
IC50 = 1000 nM
|
|
|
CP0509884
|
6-N-[(2,4-dichlorophenyl)methyl]-2-N-[5-(diethylamino)pentan-2-yl]-7-ethylpurine-2,6-diamine
Show/Hide
|
C23H33Cl2N7
|
1
|
1 |
IC50 = 1100 nM
|
|
|
CP0469578
|
5-Hydroxy-4,7-dimethyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C16H20N2O3
|
1
|
1 |
IC50 = 1130 nM
|
|
|
CP0516020
|
(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)piperazin-1-yl)(1-methylpiperidin-3-yl)methanone
Show/Hide
|
C22H27Cl2N5O2
|
1
|
1 |
IC50 = 1200 nM
|
|
|
CP0510480
|
4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N-(4-isopropylphenyl)piperazine-1-carboxamide
Show/Hide
|
C24H27N3O5
|
1
|
1 |
IC50 = 1320 nM
|
|
|
CP0387434
|
4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(pyrrolidin-1-yl)-ethoxy)-2H-chromen-2-one
Show/Hide
|
C21H29N3O3
|
1
|
1 |
IC50 = 1510 nM
|
|
|
CP0517596
|
3-(4-cinnamoylpiperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C23H22N2O5
|
1
|
1 |
IC50 = 1570 nM
|
|
|
CP0510482
|
N-benzyl-4-(5,7-dihydroxy-4-methyl-2-oxochromen-3-yl)piperazine-1-carboxamide
Show/Hide
|
C22H23N3O5
|
1
|
1 |
IC50 = 1590 nM
|
|
|
CP0501386
|
7-Ethoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C17H22N2O3
|
1
|
1 |
IC50 = 1640 nM
|
|
|
CP0437113
|
2-N-[(2,4-dichlorophenyl)methyl]-4-N-[5-(diethylamino)pentan-2-yl]quinazoline-2,4-diamine
Show/Hide
|
C24H31Cl2N5
|
1
|
1 |
IC50 = 1910 nM
|
|
|
CP0405365
|
2-N-[(2,4-dichlorophenyl)methyl]-6-N-[5-(diethylamino)pentan-2-yl]-7H-purine-2,6-diamine
Show/Hide
|
C21H29Cl2N7
|
1
|
1 |
IC50 = 2100 nM
|
|
|
CP0517598
|
N-[4-[4-(5,7-dihydroxy-4-methyl-2-oxochromen-3-yl)piperazin-1-yl]sulfonylphenyl]acetamide
Show/Hide
|
C22H23N3O7S
|
1
|
1 |
IC50 = 2560 nM
|
|
|
CP0449314
|
2-N-[(2,4-dichlorophenyl)methyl]-6-N-[5-(diethylamino)pentan-2-yl]-7-ethylpurine-2,6-diamine
Show/Hide
|
C23H33Cl2N7
|
1
|
1 |
IC50 = 2600 nM
|
|
|
CP0501387
|
7-(4-Ethylcyclohexyloxy)-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C23H32N2O3
|
1
|
1 |
IC50 = 3120 nM
|
|
|
CP0535902
|
4-N-[(2,4-dichlorophenyl)methyl]-2-N-[5-(diethylamino)pentan-2-yl]-6-N-methyl-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C20H31Cl2N7
|
1
|
1 |
IC50 = 3600 nM
|
|
|
CP0517597
|
3-(4-Acryloylpiperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C17H18N2O5
|
1
|
1 |
IC50 = 4240 nM
|
|
|
CP0494417
|
3-(4-benzoylpiperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C21H20N2O5
|
1
|
1 |
IC50 = 4360 nM
|
|
|
CP0510491
|
5,7-Dihydroxy-4-methyl-3-(piperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C14H16N2O4
|
1
|
1 |
IC50 = 4360 nM
|
|
|
CP0387431
|
7-(Dimethylamino)-4-methyl-3-(4-methylpiperazin-1-yl)-2Hchromen-2-one
Show/Hide
|
C17H23N3O2
|
1
|
1 |
IC50 = 4760 nM
|
|
|
CP0425630
|
6-N-[(2,4-dichlorophenyl)methyl]-2-N-[5-(diethylamino)pentan-2-yl]-7H-purine-2,6-diamine
Show/Hide
|
C21H29Cl2N7
|
1
|
1 |
IC50 = 4900 nM
|
|
|
CP0501385
|
7-Methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C16H20N2O3
|
1
|
1 |
IC50 = 5210 nM
|
|
|
CP0456936
|
N-[(2S)-1-[[4-[(2,4-dichlorophenyl)methoxy]pyrimidin-2-yl]amino]-3-methylbutan-2-yl]-1-methylpiperidine-3-carboxamide
Show/Hide
|
C23H31Cl2N5O2
|
1
|
1 |
IC50 = 5600 nM
|
|
|
CP0510481
|
4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N-(2-phenoxyphenyl)piperazine-1-carboxamide
Show/Hide
|
C27H25N3O6
|
1
|
1 |
IC50 = 6000 nM
|
|
|
CP0510479
|
5,7-Dihydroxy-4-methyl-3-(4-(phenylsulfonyl)piperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C20H20N2O6S
|
1
|
1 |
IC50 = 6040 nM
|
|
|
CP0541630
|
7-(4-Methoxybenzyloxy)-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C23H26N2O4
|
1
|
1 |
IC50 = 7320 nM
|
|
|
CP0373373
|
3-(4-(2-Chloroacetyl)piperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C16H17ClN2O5
|
1
|
1 |
IC50 = 8580 nM
|
|
|
CP0442870
|
1-(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)piperazin-1-yl)-2-(1-methyl-1H-imidazol-4-yl)ethanone
Show/Hide
|
C21H22Cl2N6O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0456935
|
1-(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)piperazin-1-yl)-2-(pyridin-3-yl)ethanone
Show/Hide
|
C22H21Cl2N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0464679
|
(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(piperidin-4-yl)methanone
Show/Hide
|
C21H26Cl2N6O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0464680
|
N-[3-[[4-[(2,4-dichlorophenyl)methoxy]pyrimidin-2-yl]amino]propyl]-1-methylpiperidine-3-carboxamide
Show/Hide
|
C21H27Cl2N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0492075
|
(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)piperazin-1-yl)(pyridin-3-yl)methanone
Show/Hide
|
C21H19Cl2N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0516019
|
N-[2-[[4-[(2,4-dichlorophenyl)methoxy]pyrimidin-2-yl]amino]ethyl]-1-methylpiperidine-3-carboxamide
Show/Hide
|
C20H25Cl2N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0525177
|
(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)piperazin-1-yl)(azetidin-3-yl)methanone
Show/Hide
|
C19H22Cl2N6O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0423568
|
3-(4-(2-Ethylbutyl)piperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C20H28N2O4
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0510486
|
5,7-Dihydroxy-3-(4-(2-methoxyphenyl)piperazin-1-yl)-4-methyl-2H-chromen-2-one
Show/Hide
|
C21H22N2O5
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0510485
|
5,7-Dihydroxy-4-methyl-3-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)-2H-chromen-2-one
Show/Hide
|
C21H19F3N2O4
|
1
|
1 |
IC50 = 15100 nM
|
|
|
CP0510488
|
3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C22H24N2O4
|
1
|
1 |
IC50 = 31300 nM
|
|
|
CP0430738
|
3-(4-(4-Fluorophenyl)piperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one
Show/Hide
|
C20H19FN2O4
|
1
|
1 |
IC50 = 58500 nM
|
|
|