Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01503 , Signal transducer and activator of transcription 3
Gene Name STAT3
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P40763
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01503
 
Compound ID Compound Name Compound Formula
CP0546239
N-[2-[4-[5-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]pentyl]piperidin-1-yl]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C38H39N5O8
 1
1
IC50 = 900 nM
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CP0535102
N-[2-[4-[5-[[2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]pentyl]piperidin-1-yl]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C39H41N5O8
 1
1
IC50 = 1700 nM
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CP0570705
N-[2-[2-[2-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C40H44N4O14
 1
1
IC50 = 2500 nM
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CP0528312
N-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C34H32N4O11
 1
1
IC50 = 2600 nM
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CP0561801
N-[2-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C36H36N4O12
 1
1
IC50 = 2700 nM
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CP0329823
2-Acetylfuranonaphthoquinone
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C14H8O4
 1
1
IC50 = 3200 nM
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CP0553317
N-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]ethoxy]ethoxy]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C32H28N4O10
 1
1
IC50 = 3400 nM
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CP0444131
N-[5-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]pent-4-ynyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C31H21N3O8
 1
1
IC50 = 4200 nM
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CP0425281
N-[5-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]pentyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C31H26N4O8
 1
1
IC50 = 4600 nM
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CP0444132
N-[4-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxybutyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C30H23N3O9
 1
1
IC50 = 5700 nM
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CP0444133
N-[4-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]butyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C32H26N4O10
 1
1
IC50 = 10300 nM
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CP0575045
N-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C32H30N4O9
 1
1
IC50 = 10900 nM
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CP0552793
(2S,4R)-1-[(2S)-2-[[2-[2-[2-[(4,9-dioxobenzo[f][1]benzofuran-2-carbonyl)amino]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
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C41H45N5O10S
 1
1
IC50 = 11400 nM
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CP0565883
N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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C28H20N4O8
 1
1
IC50 = 15300 nM
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CP0565884
(2S,4R)-1-[(2S)-2-[[2-[2-[(4,9-dioxobenzo[f][1]benzofuran-2-carbonyl)amino]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
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C39H41N5O9S
 1
1
IC50 > 30000 nM
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