| Compound ID |
Compound Name |
Compound Formula |
|
CP0059487
|
8-(oxan-4-yl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C25H30N2O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0245168
|
8-cyclopentyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C25H30N2O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0340822
|
8-cyclohexyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C26H32N2O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0095061
|
2,7,7-trimethyl-9-[1-oxo-8-(propan-2-ylamino)-3,4-dihydro-2H-isoquinolin-6-yl]-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one
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|
C26H34N4O2
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0095064
|
8-(4-fluorophenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C26H25FN2O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0116672
|
8-(3-fluorophenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C26H25FN2O2
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0158007
|
2-(thian-4-ylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C26H34N4O2S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0157822
|
2-(cyclopentylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C26H34N4O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0200791
|
2-fluoro-6-[[(3S)-oxolan-3-yl]amino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C25H31FN4O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0249164
|
2-[[(3S)-oxolan-3-yl]amino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C25H32N4O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0158008
|
2-(propan-2-ylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C24H32N4O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0095063
|
2,7,7-trimethyl-9-[8-(2-methylpropyl)-1-oxo-3,4-dihydro-2H-isoquinolin-6-yl]-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one
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|
C27H35N3O2
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0124122
|
2-(propylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C24H32N4O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0158006
|
2-(cyclopropylmethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C25H32N4O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0371376
|
8-cyclobutyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C24H28N2O2
|
1
|
| 1 |
IC50 = 195 nM
|
|
|
|
CP0059058
|
2-(2,2-difluoroethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C23H28F2N4O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0314115
|
8-(2-methylpropyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C24H30N2O2
|
1
|
| 1 |
IC50 = 222 nM
|
|
|
|
CP0157827
|
8-phenyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C26H26N2O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0116673
|
8-(4-methoxyphenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C27H28N2O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0178497
|
2-(cyclopropylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C24H30N4O2
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0366180
|
2-[(3-methyloxetan-3-yl)methylamino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C26H34N4O3
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0340818
|
8-benzyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C27H28N2O2
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0341208
|
4-(7,7-dimethyl-5-oxo-1,2,3,4,6,8-hexahydrocarbazol-9-yl)-2-[[(3S)-oxolan-3-yl]amino]benzamide
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|
C25H31N3O3
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0366179
|
2-(2-methoxyethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C24H32N4O3
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0116671
|
2-(2,2-dimethylpropylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C26H36N4O2
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
|
CP0178496
|
8-butyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C24H30N2O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0059491
|
8-tert-butyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
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|
C24H30N2O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0340817
|
2-(2-cyclopropylethyl)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide
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|
C26H33N3O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0173498
|
2,7,7-trimethyl-9-(1-oxo-3,4-dihydro-2H-isoquinolin-6-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one
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|
C23H27N3O2
|
1
|
| 1 |
IC50 = 8500 nM
|
|
|
|
CP0173499
|
2,7,7-trimethyl-9-(1-oxo-2,3,4,5-tetrahydro-2-benzazepin-7-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one
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|
C24H29N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0178493
|
2,7,7-trimethyl-9-(1-oxo-2,3-dihydroisoindol-5-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one
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|
C22H25N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
