Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01462 , Bromodomain-containing protein 4
 Protein Info 
Gene Name BRD4
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O60885
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01462
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0134636
 Compound Info 
(7R)-2-[2-ethoxy-4-(1-methylpiperidin-4-yl)anilino]-7-ethyl-5-methyl-8-[(4-methylthiophen-2-yl)methyl]-7H-pteridin-6-one
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C29H38N6O2S
  1
1
IC50 = 260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0044060
 Compound Info 
4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
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C28H39N7O3
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0142866
 Compound Info 
(7R)-2-[2-ethoxy-4-(1-methylpiperidin-4-yl)anilino]-7-ethyl-5-methyl-8-[(3-methylthiophen-2-yl)methyl]-7H-pteridin-6-one
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C29H38N6O2S
  1
1
IC50 = 310 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558155
 Compound Info 
N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]-2-[[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]pyrimidin-4-yl]amino]acetamide
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C30H29F3N8O4
  1
1
IC50 = 517 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0350379
 Compound Info 
(7R)-8-benzyl-2-[2-ethoxy-4-(1-methylpiperidin-4-yl)anilino]-7-ethyl-5-methyl-7H-pteridin-6-one
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C30H38N6O2
  1
1
IC50 = 540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0472999
 Compound Info 
N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]-2-[[2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]amino]acetamide
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C24H27N7O5
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0121388
 Compound Info 
5-amino-N-(2,6-dioxopiperidin-3-yl)quinoline-8-carboxamide
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C15H14N4O3
  1
1
IC50 = 2900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516483
 Compound Info 
N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]-2-[[2-(N-methylanilino)pyrimidin-4-yl]amino]acetamide
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C26H25N7O4
  1
1
IC50 = 3440 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0003304
 Compound Info 
191732-72-6
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C13H13N3O3
  1
1
IC50 = 5190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0139123
 Compound Info 
4-amino-N-(2,6-dioxopiperidin-3-yl)quinoline-8-carboxamide
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C15H14N4O3
  1
1
IC50 = 7700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS