Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01176 , cGMP-specific 3',5'-cyclic phosphodiesterase
 Protein Info 
Gene Name PDE5A
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O76074
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01176
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0419693
 Compound Info 
[4-[5-tert-butyl-3-(2,3-difluoro-4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C26H32F2N4O2
  1
1
EC50 = 4100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0000847
 Compound Info 
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
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C22H19N3O4
  1
1
EC50 = 5810 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0365459
 Compound Info 
[4-[5-tert-butyl-3-(3,5-difluoro-4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C26H32F2N4O2
  1
1
EC50 = 6700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0176508
 Compound Info 
[4-[3-(3-fluoro-4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C29H31FN4O2
  1
1
EC50 = 13800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0444327
 Compound Info 
[4-[3-(4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
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C29H32N4O2
  1
1
EC50 = 18400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS