| Compound ID |
Compound Name |
Compound Formula |
|
CP0422910
|
8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C23H35N3O
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 0.082 nM
|
|
|
|
CP0437276
|
8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C22H33N3O
|
2
|
| 1 |
EC50 = 38.02 nM
|
|
|
| 2 |
Ki = 0.079 nM
|
|
|
|
CP0038350
|
(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-phenylpropanamido]acetamido}acetamido)-3-phenylpropanamido]-3-hydroxybutanamido]acetamido}propanamido]-5-carbamimidamidopentanamido]hexanamido]-3-hydroxypropanamido]propanamido]-5-carbamimidamidopentanamido]hexanamido]-4-methylpentanamido]propanamido]butanediamido]-4-carbamoylbutanoic acid
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|
C79H129N27O22
|
2
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
Kd = 0.1 nM
|
|
|
|
CP0405159
|
8-Cyclononyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C22H33N3O
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0038465
|
8-(R)-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H25N3O
|
1
|
| 1 |
Ki = 0.41 nM
|
|
|
|
CP0402338
|
8-Cycloundecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C24H37N3O
|
1
|
| 1 |
Ki = 0.49 nM
|
|
|
|
CP0431654
|
8-Cyclododecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H39N3O
|
1
|
| 1 |
Ki = 0.95 nM
|
|
|
|
CP0402390
|
8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H37N3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0441527
|
8-Cyclooctyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C21H31N3O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0405179
|
1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C22H33N3O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0414949
|
8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C23H35N3O
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0460264
|
8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C22H33N3O
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0422928
|
8-Cycloheptyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C20H29N3O
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0379320
|
8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C20H29N3O
|
1
|
| 1 |
Ki = 7.1 nM
|
|
|
|
CP0402349
|
8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C23H35N3O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0402183
|
8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C19H27N3O
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0376605
|
8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C20H29N3O
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0409414
|
1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C22H33N3O
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0402351
|
8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H37N3O
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0405276
|
8-Cyclopentadecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C28H45N3O
|
1
|
| 1 |
Ki = 600 nM
|
|
|
