Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01130 , Activin receptor type-1B
 Protein Info 
Gene Name ACVR1B
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P36896
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01130
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0505213
 Compound Info 
N,N-dimethyl-3-[5-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]pyridin-2-yl]oxypropan-1-amine
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C23H24N6O
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0330405
 Compound Info 
N,N-dimethyl-2-[4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]phenoxy]ethanamine
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C23H23N5O
  1
1
IC50 = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0452298
 Compound Info 
1-methyl-4-[5-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]pyridin-2-yl]piperazine
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C23H23N7
  1
1
IC50 = 108 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0458349
 Compound Info 
2-(1-methylpyrazol-4-yl)-4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridine
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C17H14N6
  1
1
IC50 = 224 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0482146
 Compound Info 
2-pyrazol-1-yl-4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridine
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C16H12N6
  1
1
IC50 = 882 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0459894
 Compound Info 
2-imidazol-1-yl-4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridine
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C16H12N6
  1
1
IC50 = 956 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0025391
 Compound Info 
4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide
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C25H23N5O2
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS