Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01046 , Serine/threonine-protein kinase SIK3
 Protein Info 
Gene Name SIK3
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q9Y2K2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01046
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0004106
 Compound Info 
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
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C28H26N4O3
  1
1
IC50 = 460 nM
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CP0568788
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(3-fluoro-6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C25H24ClFN6O3
  1
1
IC50 = 7000 nM
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CP0577426
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(3-chloropyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C24H22Cl2N6O3
  1
1
IC50 = 9000 nM
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CP0550534
 Compound Info 
HG-9-91-01 (1)
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C32H37N7O3
  1
1
IC50 = 9600 nM
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CP0574243
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(3-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C25H25ClN6O3
  1
1
IC50 = 14000 nM
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CP0070883
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C25H25ClN6O3
  1
1
IC50 = 24000 nM
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CP0550539
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-[6-(difluoromethyl)pyridin-2-yl]phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C25H23ClF2N6O3
  1
1
IC50 = 50000 nM
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CP0579760
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methoxypyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C25H25ClN6O4
  1
1
IC50 = 80000 nM
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CP0577014
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(2-methoxyanilino)pyrido[2,3-d]pyrimidin-7-one
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C31H29ClN6O4
  1
1
IC50 = 83000 nM
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CP0580152
 Compound Info 
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(3-methoxy-6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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C26H27ClN6O4
  1
1
IC50 = 84000 nM
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