Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT00973 , Methionine aminopeptidase 2
Gene Name METAP2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P50579
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT00973
 
Compound ID Compound Name Compound Formula
CP0757713
(S)-3-Hydroxy-2-oxo-1-(1H-pyrrolo[2,3-b]pyridin-5-yl)-pyrrolidine-3-carboxylic Acid 3,5-Difluoro-benzylamide
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C19H16F2N4O3
 2
1
Kd = 0.88 nM
   TI
   LI
   LO
   TS
2
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0371532
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolidine-3-carboxamide
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C19H16ClFN4O3
 2
1
Kd = 1.14 nM
   TI
   LI
   LO
   TS
2
Ki = 3.36 nM
   TI
   LI
   LO
   TS
CP0355582
(3S)-N-[(3,5-difluorophenyl)methyl]-3-hydroxy-1-(1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide
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C20H17F2N3O3
 2
1
Kd = 2.1 nM
   TI
   LI
   LO
   TS
2
Ki = 4.33 nM
   TI
   LI
   LO
   TS
CP0164309
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
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C21H19ClFN3O4
 1
1
Ki = 0.16 nM
   TI
   LI
   LO
   TS