| Compound ID |
Compound Name |
Compound Formula |
|
CP0576354
|
(E)-2-cyano-3-[3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]prop-2-enamide
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|
C16H11N5O
|
1
|
| 1 |
IC50 = 0.2512 nM
|
|
|
|
CP0579620
|
US9505766, 81
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|
C24H26N4O5
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0577364
|
5-(4-chloropyrimidin-2-yl)pyrrolo[3,2-d]pyrimidine
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|
C10H6ClN5
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0570214
|
6-chloro-2-pyrrolo[3,2-d]pyrimidin-5-ylpyridine-3-carbonitrile
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|
C12H6ClN5
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
|
CP0570190
|
1-(5-chloro-2-fluoropyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C11H6ClFN4
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0573655
|
5-(2,5-dichloropyrimidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine
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|
C10H5Cl2N5
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0569213
|
5-(2,5-dichloropyrimidin-4-yl)pyrrolo[3,2-d]pyrimidine
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|
C10H5Cl2N5
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0579107
|
5-(5-bromo-2-chloropyrimidin-4-yl)pyrrolo[3,2-d]pyrimidine
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|
C10H5BrClN5
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0547255
|
1-(2,5-dichloropyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C11H6Cl2N4
|
3
|
| 1 |
IC50 = 63.1 nM
|
|
|
| 2 |
IC50 = 125.89 nM
|
|
|
| 3 |
IC50 = 2511.89 nM
|
|
|
|
CP0568109
|
1-(4-chloropyrimidin-2-yl)pyrrolo[3,2-b]pyridine
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|
C11H7ClN4
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0569212
|
3-(2,5-dichloropyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridine
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|
C11H6Cl2N4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0574511
|
2-chloro-6-pyrrolo[3,2-d]pyrimidin-5-ylpyridine-3-carbonitrile
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|
C12H6ClN5
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0577669
|
1-[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]pyrrolo[3,2-b]pyridine
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|
C12H6ClF3N4
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0577670
|
1-(2-bromo-5-chloropyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C11H6BrClN4
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0579091
|
1-(4-chloro-5-methylpyrimidin-2-yl)pyrrolo[3,2-b]pyridine
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|
C12H9ClN4
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0579639
|
1-(2-chloro-5-fluoropyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C11H6ClFN4
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0573656
|
1-(2-chloropyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C11H7ClN4
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0569401
|
5-chloro-4-pyrrolo[3,2-b]pyridin-1-ylpyrimidine-2-carbonitrile
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|
C12H6ClN5
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0577672
|
1-(5-chloropyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C11H7ClN4
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0577363
|
1-(5-chloro-2-methylsulfanylpyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C12H9ClN4S
|
1
|
| 1 |
IC50 = 17782.79 nM
|
|
|
|
CP0575996
|
1-(2-chloro-5-methylpyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C12H9ClN4
|
1
|
| 1 |
IC50 = 19952.62 nM
|
|
|
|
CP0579207
|
1-pyrimidin-4-ylpyrrolo[3,2-b]pyridine
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|
C11H8N4
|
1
|
| 1 |
IC50 = 19952.62 nM
|
|
|
|
CP0576011
|
1-(5-chloro-2-methylpyrimidin-4-yl)pyrrolo[3,2-b]pyridine
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|
C12H9ClN4
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0576355
|
1-(6-chloropyridin-2-yl)pyrrolo[3,2-b]pyridine
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|
C12H8ClN3
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0576539
|
1-pyrimidin-2-ylpyrrolo[3,2-b]pyridine
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|
C11H8N4
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0577386
|
1-(3,6-dichloropyridin-2-yl)pyrrolo[3,2-b]pyridine
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|
C12H7Cl2N3
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0580244
|
1-(2,5-dichlorophenyl)pyrrolo[3,2-b]pyridine
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|
C13H8Cl2N2
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
