Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT00635 , Purinergic receptor P2Y14
Gene Name P2RY14
Organism Pan troglodytes, Chimpanzee
Protein Classification Membrane receptor
Uniprot ID A0A2J8P2M1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT00635
 
Compound ID Compound Name Compound Formula
CP0032210
4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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C29H24F3NO2
 1
1
IC50 = 2.2 nM
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CP0880983
4-(4-Imidazo[1,2-a]pyrimidin-2-yl-phenyl)-7-(4-trifluoromethylphenyl)-2-naphthoic acid
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C30H18F3N3O2
 1
1
IC50 = 3 nM
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CP0341302
(R)-4-(4-(2,2-difluoro-1-hydroxyethyl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid
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C26H17F5O3
 1
1
IC50 = 5.4 nM
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CP0880982
4-[4-(4-hydroxypiperidin-4-yl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthoic acid
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C29H24F3NO3
 1
1
IC50 = 6.3 nM
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CP0863205
4-[5-(2,2-Difluoro-1-hydroxyethyl)-3-thienyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthoic acid
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C24H15F5O3S
 1
1
IC50 = 7.1 nM
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CP0901902
4-(3-Thienyl)-7-[(2,3,6-trichlorobenzyl)oxy]-2-naphthoic acid
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C22H13Cl3O3S
 1
1
IC50 = 7.3 nM
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CP0880981
7-[(3,5-Dichloropyridin-4-yl)methoxy]-4-(3-thienyl)-2-naphthoic acid
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C21H13Cl2NO3S
 1
1
IC50 = 7.5 nM
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CP0877389
7-[(2,6-Dichlorobenzyl)oxy]-4-(3-thienyl)-2-naphthoic acid
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C22H14Cl2O3S
 1
1
IC50 = 9.4 nM
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CP0852690
4-(3-Thienyl)-7-[(2,4,6-trifluorobenzyl)oxy]-2-naphthoic acid
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C22H13F3O3S
 1
1
IC50 = 10.5 nM
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CP0852689
4-(4-Carboxyphenyl)-7-[(2,6-dimethylbenzyl)oxy]-2-naphthoic acid
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C27H22O5
 1
1
IC50 = 11 nM
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CP0425968
(R)-4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid
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C26H16F6O3
 1
1
IC50 = 11.3 nM
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CP0872889
7-[(2,6-Dimethylbenzyl)oxy]-4-[4-(methylsulfonyl)phenyl]-2-naphthoic acid
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C27H24O5S
 1
1
IC50 = 11.9 nM
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CP0903817
4-[5-(Methylsulfonyl)-3-thienyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthoic acid
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C23H15F3O4S2
 1
1
IC50 = 12.2 nM
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CP0859363
4-{4-[(1R)-2,2-Difluoro-1-hydroxyethyl]phenyl}-7-[4-(methylthio)phenyl]-2-naphthoic acid
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C26H20F2O3S
 1
1
IC50 = 12.4 nM
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CP0859921
7-[(2-Chloro-6-fluorobenzyl)oxy]-4-(3-thienyl)-2-naphthoic acid
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C22H14ClFO3S
 1
1
IC50 = 12.5 nM
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CP0422868
4-(thiophen-3-yl)-7-(4-(trifluoromethoxy)phenyl)-2-naphthoic acid
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C22H13F3O3S
 1
1
IC50 = 12.7 nM
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CP0502633
4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid
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C26H16F6O3
 1
1
IC50 = 13 nM
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CP0868950
4-[4-(4H-[1,2,4]Triazol-3-yl)-phenyl]-7-(4-trifluoromethylphenyl)-2-naphthoic acid
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C26H16F3N3O2
 1
1
IC50 = 13.3 nM
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CP0931118
4-[4-(Methylsulfinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthoic acid
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C25H17F3O3S
 1
1
IC50 = 13.9 nM
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CP0866704
4-{4-[(1R)-2,2-Difluoro-1-hydroxyethyl]phenyl}-7-(4-fluorophenyl)-2-naphthoic acid
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C25H17F3O3
 1
1
IC50 = 14 nM
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CP0921252
7-[(2,6-Dimethylbenzyl)oxy]-4-[(2-methoxybenzyl)oxy]-2-naphthoic acid
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C26H22O5
 1
1
IC50 = 14.1 nM
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CP0531346
7-(4-fluoro-2,6-dimethylbenzyloxy)-4-(thiophen-3-yl)-2-naphthoic acid
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C24H19FO3S
 1
1
IC50 = 14.4 nM
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CP0867185
7-[2,6-Dimethylbenzyloxy]-4-[4-(1-hydroxy-1-methylethyl)phenyl]-2-naphthoic acid
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C29H28O4
 1
1
IC50 = 16.1 nM
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CP0438203
7-(2,6-dimethylbenzyloxy)-4-(thiophen-3-yl)-2-naphthoic acid
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C24H20O3S
 1
1
IC50 = 16.3 nM
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CP0864724
7-[(2,6-Dimethylbenzyl)oxy]-4-[4-(hydroxymethyl)phenyl]-2-naphthoic acid
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C27H24O4
 1
1
IC50 = 16.6 nM
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CP0877365
7-{[2-Methyl-5-(trifluoromethyl)benzyl]oxy}-4-(3-thienyl)-2-naphthoic acid
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C24H17F3O3S
 1
1
IC50 = 16.8 nM
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CP0894080
4-(4-Acetylphenyl)-7-[(2,6-dimethylbenzyl)oxy]-2-naphthoic acid
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C28H24O4
 1
1
IC50 = 17.5 nM
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CP0952223
7-[(2-Bromo-6-chlorobenzyl)oxy]-4-(3-thienyl)-2-naphthoic acid
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C22H14BrClO3S
 1
1
IC50 = 17.8 nM
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CP0852688
7-[(2,6-Dimethylbenzyl)oxy]-4-(4-hydroxyphenyl)-2-naphthoic acid
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C26H22O4
 1
1
IC50 = 18.4 nM
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CP0873838
4-(1,3-Benzodioxol-5-yl)-7-[(2,6-dimethylbenzyl)oxy]-2-naphthoic acid
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C27H22O5
 1
1
IC50 = 19.4 nM
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CP0864722
7-[(6-Chloro-2-fluoro-3-methylbenzyl)oxy]-4-(3-thienyl)-2-naphthoic acid
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C23H16ClFO3S
 1
1
IC50 = 20.3 nM
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CP0522044
4-(benzyloxy)-7-(2,6-dimethylbenzyloxy)-2-naphthoic acid
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C27H24O4
 1
1
IC50 = 21.2 nM
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CP0873879
4-Phenyl-7-[(2,3,6-trichlorobenzyl)oxy]-2-naphthoic acid
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C24H15Cl3O3
 1
1
IC50 = 21.7 nM
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CP0943025
7-[(2,6-Dimethylbenzyl)oxy]-4-(4-formylphenyl)-2-naphthoic acid
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C27H22O4
 1
1
IC50 = 22.5 nM
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CP0952222
7-[(2,6-Difluorobenzyl)oxy]-4-(3-thienyl)-2-naphthoic acid
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C22H14F2O3S
 1
1
IC50 = 22.6 nM
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CP0873878
4-[5-(Methylsulfonyl)-3-thienyl]-7-[4-(trifluoromethoxy)phenyl]-2-naphthoic acid
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C23H15F3O5S2
 1
1
IC50 = 23.9 nM
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CP0940855
7-[(2,6-Dibromobenzyl)oxy]-4-(3-thienyl)-2-naphthoic acid
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C22H14Br2O3S
 1
1
IC50 = 24.3 nM
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CP0952221
(R)-4-(4-(2,2-difluoro-1-hydroxyethyl)phenyl)-3-fluoro-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid
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C26H16F6O3
 1
1
IC50 = 24.8 nM
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CP0943024
(S)-3-fluoro-4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid
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C26H15F7O3
 1
1
IC50 = 25.5 nM
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CP0952220
7-{[2-Chloro-5-(trifluoromethyl)benzyl]oxy}-4-(3-thienyl)-2-naphthoic acid
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C23H14ClF3O3S
 1
1
IC50 = 26 nM
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